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anti-ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) Antibodies

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Additionally we are shipping ATG4B Proteins (13) and ATG4B Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATG4B 23192 Q9Y4P1
ATG4B 66615 Q8BGE6
ATG4B 316640  
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Top anti-ATG4B Antibodies at antibodies-online.com

Showing 10 out of 137 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ATG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-ATG4B AntibodyTitration: 2.5 µg/mL  Positive Control... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of APG4B (arrow) using purified polyclonal antib... Formalin-fixed and paraffin-embedded human skeletal muscle reacted wit... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB ATG4B/MB10290 antibody   western blot analysis in MCF-7 cell line lysa... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-hAPG4B-R31 Pab (ABIN388494) in 293 cell ... The anti-APG4B Pab (ABIN388494) is used in Western blot to detect APG4... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human skeletal muscle reacted wit... Western blot analysis of APG4B (arrow) using APG4B / ATG4B Antibody . ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... APG4B / ATG4B Antibody used in Western blot to detect APG4B in CEM tis... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of anti-hAPG4B-373 Pab (ABIN1882065) in 293 cell... Western blot analysis of anti-hAPG4B-373 Pab (ABIN1882065) in 293 cell... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ATG4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... WB Suggested Anti-ATG4B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: ... 100 μL Log in to see 2 to 3 Days
$289.00
Details

ATG4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,

Top referenced anti-ATG4B Antibodies

  1. Human Polyclonal ATG4B Primary Antibody for IHC (p), WB - ABIN388494 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 6 references for ABIN388494

  2. Human Polyclonal ATG4B Primary Antibody for EIA, IHC (p) - ABIN1449637 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 6 references for ABIN1449637

  3. Human Polyclonal ATG4B Primary Antibody for IF, IHC (p) - ABIN1882065 : Pontén, Westermark: Properties of human malignant glioma cells in vitro. in Medical biology 1978 (PubMed)
    Show all 6 references for ABIN1882065

  4. Human Polyclonal ATG4B Primary Antibody for EIA, IHC (p) - ABIN1449638 : Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. in Developmental cell 2005 (PubMed)
    Show all 5 references for ABIN1449638

  5. Human Polyclonal ATG4B Primary Antibody for IHC (p), WB - ABIN388497 : Tanida, Sou, Ezaki, Minematsu-Ikeguchi, Ueno, Kominami: HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN388497

  6. Human Monoclonal ATG4B Primary Antibody for WB - ABIN659121 : Satoo, Noda, Kumeta, Fujioka, Mizushima, Ohsumi, Inagaki: The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. in The EMBO journal 2009 (PubMed)

  7. Dog (Canine) Polyclonal ATG4B Primary Antibody for WB - ABIN2775794 : Kumanomidou, Mizushima, Komatsu, Suzuki, Tanida, Sou, Ueno, Kominami, Tanaka, Yamane: The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. in Journal of molecular biology 2005 (PubMed)

  8. Chicken Polyclonal ATG4B Primary Antibody for WB - ABIN2787433 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against ATG4B Interaction Partners

Arabidopsis thaliana ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. These results support the conclusion that CML24 affects autophagy progression through interactions with ATG4.

  2. AtATG4a is catalytically more active and has broad AtATG8 substrate specificity compared with AtATG4b. [ATG4b]

Xenopus laevis ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

Human ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. Purified ATG4B protein interact with LC3B (show MAP1LC3B Antibodies) in vitro.

  2. ATG4B independently plays a role as a positive regulator on tumor proliferation and a negative regulator on autophagy in colorectal cancer cells.

  3. This study identifies ATG4B as a potential biomarker for predicting therapeutic response in treatment-naive chronic myeloid leukemia (show BCL11A Antibodies) stem/progenitor cells and uncovers ATG4B as a possible drug target in these cells.

  4. The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts.

  5. Atg4B possessed the broadest spectrum against all substrates, followed by Atg4A (show ATG4A Antibodies) for ATG8 (show GABARAPL2 Antibodies) substrates

  6. HsAtg4B negatively regulates the localization of LC3 (show MAP1LC3A Antibodies) to a membrane compartment by delipidation

  7. crystal structure of human Atg4b by X-ray crystallography at 2.0 A resolution, and show that Atg4b is a cysteine protease (show CTSB Antibodies) whose active catalytic triad site consists of Cys74, His280 and Asp278

  8. Murine Atg8L/Apg8L (show GABARAPL1 Antibodies) modification is mediated by human Atg4B.

  9. The crystal structures of catalytically inert human Atg4B in complex with processed and unprocessed forms of LC3 (show MAP1LC3A Antibodies) showed that, on LC3 (show MAP1LC3A Antibodies) binding, the regulatory loop and the N-terminal tail of HsAtg4B undergo large conformational changes.

Mouse (Murine) ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. miR (show MLXIP Antibodies)-34a might regulate the autophagic activity and can cause injury in ischemia reperfusion injured renal tubular epithelial cells (RTEC) via targeting Atg4B. Atg4B knockdown inhibited autophagy in RTECs.

  2. the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis

  3. REDD1 (show DDIT4 Antibodies)/TXNIP (show TXNIP Antibodies) complex expression is sufficient to induce reactive oxygen species, suppress ATG4B activity and activate autophagy.

  4. these findings demonstrate a role for Ser (show SIGLEC1 Antibodies)-383 and Ser (show SIGLEC1 Antibodies)-392 phosphorylation of ATG4B in control of autophagy.

  5. mTOR (show FRAP1 Antibodies) inhibition alleviates Huntington's disease progression by inducing Atg4b-dependent autophagic flux.

  6. An autophagy-related gene, Atg4b, is identified as a de novo target gene of C/EBP BETA (show CEBPB Antibodies) and is shown to play an important role in 3T3-L1 adipocyte differentiation.

  7. the RNF5-mediated control of membranalATG4B reveals a novel layer in the regulation of LC3 (show MAP1LC3A Antibodies) processing and autophagy.

  8. The Atg4b participates in polarized secretion of lysosomal contents into the extracellular space by directing lysosomes to fuse with the plasma membrane.

  9. Genetic inactivation of mouse Atg4b resulted in amorphous globular bodies in the neuropil of the deep cerebellar nuclei and adjacent vestibular nuclei and a mild but measurable impairment of motor performance on the Rotarod.

  10. The Apg4B/autophagin-1 protease thus serves as a processing/deconjugating enzyme for these four highly divergent mammalian Apg8 homologues, GATE-16 (show GABARAPL2 Antibodies), MAP1 (show MOAP1 Antibodies)-LC3 (show MAP1LC3A Antibodies), GABARAP (show GABARAP Antibodies), and Apg8L (show GABARAPL1 Antibodies).

ATG4B Antigen Profile

Protein Summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with ATG4B

  • autophagy related 4B, cysteine peptidase (ATG4B) antibody
  • autophagy-related 4b (Atg4b) antibody
  • cysteine protease ATG4b (AT3G59950) antibody
  • cysteine protease ATG4B (Tsp_08582) antibody
  • cysteine protease ATG4B (Tsp_11599) antibody
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) (atg4b) antibody
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) (ATG4B) antibody
  • autophagy related 4B, cysteine peptidase (atg4b) antibody
  • autophagy related 4B, cysteine peptidase (Atg4b) antibody
  • 2510009N07Rik antibody
  • Apg4b antibody
  • Atg4bl antibody
  • Aut2b2 antibody
  • Autl1 antibody
  • AW048066 antibody

Protein level used designations for ATG4B

ATG4 autophagy related 4 homolog B , cysteine protease ATG4B , autophagy 4b variant 1Cysteine protease ATG4B , autophagy 4b variant 3 , cysteine protease ATG4b , APG4 autophagy 4 homolog B , autophagy-related protein 4 homolog B , AUT2B , autophagin-2B , autophagy-related cysteine endopeptidase 2B , cAut2B , AUT-like 1 cysteine endopeptidase , autophagin-1 , autophagy-related cysteine endopeptidase 1 , hAPG4B , APG4 (ATG4) autophagy-related homolog B , AUT-like 1, cysteine endopeptidase , autophagin 1 , autophagy-related 4B , cysteine protease involved in autophagy APG4-B , autophagy related 4 homolog B , autophagy related 4-like protein B , bAut2B

GENE ID SPECIES
748674 Pan troglodytes
100067797 Equus caballus
100240691 Zea mays
825165 Arabidopsis thaliana
10907016 Trichinella spiralis
10912977 Trichinella spiralis
100194746 Salmo salar
448859 Danio rerio
404750 Gallus gallus
494717 Xenopus laevis
23192 Homo sapiens
66615 Mus musculus
316640 Rattus norvegicus
609599 Canis lupus familiaris
100462747 Sus scrofa
408002 Bos taurus
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