ATG4B antibody

Catalog No. ABIN7265793

The Rabbit Monoclonal anti-ATG4B antibody (ABIN7265793) specifically detects ATG4B in WB and IF. The antibody is reactive with Human samples.

Quick Overview for ATG4B antibody (ABIN7265793)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ATG4B Antibody

Purpose: ATG4B Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ATG4B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: ATG4B

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],APG4B, AUTL1,Autophagy,Autophagy_ATGs,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Extracellular Matrix,Heart,Invasion and Metastasis,Mitochondrial metabolism,Signal Transduction,Ubiquitin,ATG4B

Molecular Weight: 44kDa

Gene ID: 23192

UniProt: Q9Y4P1

Pathways: Autophagy