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ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008].. Additionally we are shipping ATAD3A Proteins (6) and ATAD3A Kits (4) and many more products for this protein.
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Human Polyclonal ATAD3A Primary Antibody for WB - ABIN1881077
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
Show all 3 references for ABIN1881077
Human Polyclonal ATAD3A Primary Antibody for EIA, WB - ABIN783500
Patel, Latterich: The AAA team: related ATPases with diverse functions. in Trends in cell biology 1998
Show all 2 references for ABIN783500
Human Polyclonal ATAD3A Primary Antibody for IF, IP - ABIN950090
Goller, Seibold, Kremmer, Voos, Kolanus: Atad3 function is essential for early post-implantation development in the mouse. in PLoS ONE 2013
stabilization of WASF3 (show WASF3 Antibodies) function occurs through its interaction with ATAD3A and GRP78 (show HSPA5 Antibodies), which may provide a bridge between the ER and mitochondria, allowing communication between the two organelles
These results demonstrate that ATAD3-mediated mitochondrial membrane formation participates in the optimal transfer of cholesterol from the endoplasmic reticulum into mitochondria.
High ATAD3A expression correlates with radioresistance in glioblastoma.
exploring ATAD3 mRNA expression, we confirmed the existence of an alternative splicing in rodent and of several mRNA isoforms in human
ATAD3B (show ATAD3B Antibodies) is a negative regulator of ATAD3A and may function as an adaptor of mitochondrial homeostasis and metabolism in human pluripotent embryonic stem cells and cancer cells.
Engineered a high copy strain expressing human ATAD3A-Myc (show MYC Antibodies)-HIS at a relative high level (2.5mg/l of yeast culture)without significantly affecting yeast growth.Urea-denaturated ATAD3A-Myc (show MYC Antibodies)-HIS bound to agarose-nickel beads and could be renatured and eluted.
ATAD3 may be implicated in an unknown but essential and growth-linked mitochondrial function existing since pluri-cellular organization and involved in tumorigenesis.
Results show that HPV infection correlates with increased ATAD3A expression and drug resistance in uterine cervical cancer.
ATAD3 may therefore be implicated in an unknown but essential and growth-linked mitochondrial function existing since pluri-cellular -organization and involved in tumorigenesis.
silencing of ATAD3A expression reduced PSA (show PLAG1 Antibodies) secretion and cisplatin resistance, suggesting that ATAD3A was associated with PSA (show PLAG1 Antibodies) secretion and drug resistance in PCa (show FLVCR1 Antibodies).
ATAD3 is present in five native mitochondrial protein (show COX6B2 Antibodies) complexes of different sizes, indicating complex roles of the protein in mitochondrial architecture and function.
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007
ATPase family, AAA domain containing 3A
, ATPase family AAA domain-containing protein 3A
, AAA-ATPase TOB3
, ATPase family AAA domain-containing protein 3
, ATPase family, AAA domain containing 3
, ATPase family, AAA domain containing 3B