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ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008].. Additionally we are shipping ATAD3A Antibodies (40) and ATAD3A Kits (4) and many more products for this protein.
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stabilization of WASF3 (show WASF3 Proteins) function occurs through its interaction with ATAD3A and GRP78 (show HSPA5 Proteins), which may provide a bridge between the ER and mitochondria, allowing communication between the two organelles
These results demonstrate that ATAD3-mediated mitochondrial membrane formation participates in the optimal transfer of cholesterol from the endoplasmic reticulum into mitochondria.
High ATAD3A expression correlates with radioresistance in glioblastoma.
exploring ATAD3 mRNA expression, we confirmed the existence of an alternative splicing in rodent and of several mRNA isoforms in human
ATAD3B (show ATAD3B Proteins) is a negative regulator of ATAD3A and may function as an adaptor of mitochondrial homeostasis and metabolism in human pluripotent embryonic stem cells and cancer cells.
Engineered a high copy strain expressing human ATAD3A-Myc (show MYC Proteins)-HIS at a relative high level (2.5mg/l of yeast culture)without significantly affecting yeast growth.Urea-denaturated ATAD3A-Myc (show MYC Proteins)-HIS bound to agarose-nickel beads and could be renatured and eluted.
ATAD3 may be implicated in an unknown but essential and growth-linked mitochondrial function existing since pluri-cellular organization and involved in tumorigenesis.
Results show that HPV infection correlates with increased ATAD3A expression and drug resistance in uterine cervical cancer.
ATAD3 may therefore be implicated in an unknown but essential and growth-linked mitochondrial function existing since pluri-cellular -organization and involved in tumorigenesis.
silencing of ATAD3A expression reduced PSA (show PLAG1 Proteins) secretion and cisplatin resistance, suggesting that ATAD3A was associated with PSA (show PLAG1 Proteins) secretion and drug resistance in PCa (show FLVCR1 Proteins).
ATAD3 is present in five native mitochondrial protein (show COX6B2 Proteins) complexes of different sizes, indicating complex roles of the protein in mitochondrial architecture and function.
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007
ATPase family, AAA domain containing 3A
, ATPase family AAA domain-containing protein 3A
, AAA-ATPase TOB3
, ATPase family AAA domain-containing protein 3
, ATPase family, AAA domain containing 3
, ATPase family, AAA domain containing 3B