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ACAT1 encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Additionally we are shipping ACAT1 Proteins (11) and ACAT1 Kits (10) and many more products for this protein.
Showing 10 out of 152 products:
Human Polyclonal ACAT1 Primary Antibody for EIA, IHC (p) - ABIN359718
Locke, Wasan, Nelson, Guns, Leon: Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). in The Prostate 2007
Show all 3 references for ABIN359718
Human Monoclonal ACAT1 Primary Antibody for EIA, WB - ABIN1449417
Antonenkov, Croes, Waelkens, Van Veldhoven, Mannaerts: Identification, purification and characterization of an acetoacetyl-CoA thiolase from rat liver peroxisomes. in European journal of biochemistry / FEBS 2000
Show all 3 references for ABIN1449417
Human Polyclonal ACAT1 Primary Antibody for IHC (p), WB - ABIN391807
Guo, Chang, Chang: Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1. in Biochemistry 2007
Show all 2 references for ABIN391807
Cow (Bovine) Polyclonal ACAT1 Primary Antibody for EIA, IF - ABIN498064
Hongo, Watanabe, Arita, Kanome, Kageyama, Shioda, Miyazaki: Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. in American journal of physiology. Endocrinology and metabolism 2009
Chicken Polyclonal ACAT1 Primary Antibody for IHC, WB - ABIN2785629
Li, Bai, Fan: [Analysis of acyl-coenzyme A: cholesterol acyltransferase 1 polymorphism in patients with endogenous hypertriglyceridemia in Chinese population]. in Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2008
ACAT1 has a role in regulating the dynamics of free cholesterols in plasma membrane which leads to the APP (show APP Antibodies)-alpha-processing alteration
compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient
ACAT1 regulates glioblastoma-cell proliferation via modification of the Akt (show AKT1 Antibodies) and/or the ERK1/2 (show MAPK1/3 Antibodies) pathway.
Data indicate that acetyl-CoA (show LPCAT2 Antibodies) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Antibodies)) are involved in various drug-resistance-forming mechanisms.
ACAT1, ACACA (show ACACA Antibodies), ALDH6A1 (show ALDH6A1 Antibodies) and MTHFD1 (show MTHFD1 Antibodies) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.
Data show that the C allele of acyl-CoA (show GNPAT Antibodies) acyltransferase-1 (ACAT-1) rs1044925 was associated with a decreased risk of coronary artery disease and ischemic stroke patients.
Acat1 gene knock-out increases phagocytic uptake of amyloid beta-protein (1 (show DLX4 Antibodies)-42).
Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity ACAT1.
the enzyme activity of ACAT1 with Gln526 is less active than that of ACAT1 with Arg526 by 40%; Pro347 located near transmembrane domain 5 plays an important role in modulating enzyme catalysis
the pyruvate dehydrogenase (show PDP Antibodies) complex is regulated by Tyr (show TYR Antibodies) phosphorylation of PDP1 (show PDP Antibodies), which toggles recruitment between ACAT1 and SIRT3 (show SIRT3 Antibodies)
In a mouse model, targeting ACAT1 (show SOAT1 Antibodies) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.
Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Antibodies) expression and promotes VSMC foam cell formation.
Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Antibodies) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Antibodies) signaling.
ACAT1 (show SOAT1 Antibodies) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Antibodies)(-/-) mouse during atherosclerosis development.
ApoA-I (show APOA1 Antibodies) Helsinki promotes accumulation of ACAT1 (show SOAT1 Antibodies) in a mouse macrophage cell line.
the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Antibodies) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Antibodies)
ACAT1 (show SOAT1 Antibodies) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.
ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol
ACAT1 (show SOAT1 Antibodies) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.
Deficiency of macrophage ACAT1 (show SOAT1 Antibodies) accelerates atherosclerosis in apoE (show APOE Antibodies)-/- mice but has no effect when hypercholesterolemia is corrected by apoE (show APOE Antibodies) expression. ACAT1 (show SOAT1 Antibodies) deletion impairs ABCA1 (show ABCA1 Antibodies)-mediated cholesterol efflux in macrophages regardless of apoE (show APOE Antibodies) expression
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
acetyl-CoA acetyltransferase 1
, acetoacetyl Coenzyme A thiolase
, acetoacetyl-CoA thiolase
, acetyl-CoA acetyltransferase, mitochondrial
, acetyl-Coenzyme A acetyltransferase 1
, mitochondrial acetoacetyl-CoA thiolase
, acetyl-Co A acetyltransferase 1 mitochondrial
, acetyl-coenzyme A acetyltransferase 1
, Acetoacetyl-CoA thiolase A
, acetyl-CoA acetyltransferase A, mitochondrial
, acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)