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anti-Acetyl-CoA Acetyltransferase 1 (ACAT1) Antibodies

ACAT1 encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Additionally we are shipping ACAT1 Kits (13) and ACAT1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAT1 38 P24752
ACAT1 25014 P17764
ACAT1 110446 Q8QZT1
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Top anti-ACAT1 Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACAT1 Pab (ABIN391807) in SK-BR-3 cell line lysates (35 µg/lane).ACAT1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term) (ABIN391807), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IF, WB Western blot analysis: ACAT1 antibody staining of Human Liver lysate at 0.01 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western blot analysis: ACAT1 antibody staining of Mouse (A) and Rat (B) kidney lysates, and Mouse (C) and Rat (D) Liver lysates at 0.01 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-ACAT1 Pab in SK-BR-3 cell line lysates (35ug/lane).ACAT1 (arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Cow Goat Un-conjugated EIA, IF, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-ACAT1 antibody IHC staining of human liver, hepatocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959271 concentration 5 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details

ACAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ACAT1 Antibodies

  1. Human Polyclonal ACAT1 Primary Antibody for EIA, IHC (p) - ABIN359718 : Locke, Wasan, Nelson, Guns, Leon: Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). in The Prostate 2007 (PubMed)
    Show all 3 references for ABIN359718

  2. Human Monoclonal ACAT1 Primary Antibody for EIA, WB - ABIN1449417 : Antonenkov, Croes, Waelkens, Van Veldhoven, Mannaerts: Identification, purification and characterization of an acetoacetyl-CoA thiolase from rat liver peroxisomes. in European journal of biochemistry / FEBS 2000 (PubMed)
    Show all 3 references for ABIN1449417

  3. Human Polyclonal ACAT1 Primary Antibody for IHC (p), WB - ABIN391807 : Guo, Chang, Chang: Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1. in Biochemistry 2007 (PubMed)
    Show all 2 references for ABIN391807

  4. Cow (Bovine) Polyclonal ACAT1 Primary Antibody for EIA, IF - ABIN498064 : Hongo, Watanabe, Arita, Kanome, Kageyama, Shioda, Miyazaki: Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)

  5. Chicken Polyclonal ACAT1 Primary Antibody for IHC, WB - ABIN2785629 : Li, Bai, Fan: [Analysis of acyl-coenzyme A: cholesterol acyltransferase 1 polymorphism in patients with endogenous hypertriglyceridemia in Chinese population]. in Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2008 (PubMed)

More Antibodies against ACAT1 Interaction Partners

Human Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient

  2. ACAT1 regulates glioblastoma-cell proliferation via modification of the Akt (show AKT1 Antibodies) and/or the ERK1/2 (show MAPK1/3 Antibodies) pathway.

  3. Data indicate that acetyl-CoA (show LPCAT2 Antibodies) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Antibodies)) are involved in various drug-resistance-forming mechanisms.

  4. ACAT1, ACACA (show ACACA Antibodies), ALDH6A1 (show ALDH6A1 Antibodies) and MTHFD1 (show MTHFD1 Antibodies) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.

  5. Data show that the C allele of acyl-CoA (show GNPAT Antibodies) acyltransferase-1 (ACAT-1) rs1044925 was associated with a decreased risk of coronary artery disease and ischemic stroke patients.

  6. Acat1 gene knock-out increases phagocytic uptake of amyloid beta-protein (1 (show DLX4 Antibodies)-42).

  7. Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity ACAT1.

  8. the enzyme activity of ACAT1 with Gln526 is less active than that of ACAT1 with Arg526 by 40%; Pro347 located near transmembrane domain 5 plays an important role in modulating enzyme catalysis

  9. the pyruvate dehydrogenase (show PDP Antibodies) complex is regulated by Tyr (show TYR Antibodies) phosphorylation of PDP1 (show PDP Antibodies), which toggles recruitment between ACAT1 and SIRT3 (show SIRT3 Antibodies)

  10. these findings indicate that ACAT1 expression could serve as a potential prognostic marker in prostate cancer, specifically in differentiating indolent and aggressive forms of cancer.

Mouse (Murine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. In a mouse model, targeting ACAT1 (show SOAT1 Antibodies) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.

  2. Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Antibodies) expression and promotes VSMC foam cell formation.

  3. Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Antibodies) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Antibodies) signaling.

  4. ACAT1 (show SOAT1 Antibodies) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Antibodies)(-/-) mouse during atherosclerosis development.

  5. ApoA-I (show APOA1 Antibodies) Helsinki promotes accumulation of ACAT1 (show SOAT1 Antibodies) in a mouse macrophage cell line.

  6. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Antibodies) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Antibodies)

  7. ACAT1 (show SOAT1 Antibodies) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.

  8. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol

  9. ACAT1 (show SOAT1 Antibodies) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.

  10. Deficiency of macrophage ACAT1 (show SOAT1 Antibodies) accelerates atherosclerosis in apoE (show APOE Antibodies)-/- mice but has no effect when hypercholesterolemia is corrected by apoE (show APOE Antibodies) expression. ACAT1 (show SOAT1 Antibodies) deletion impairs ABCA1 (show ABCA1 Antibodies)-mediated cholesterol efflux in macrophages regardless of apoE (show APOE Antibodies) expression

ACAT1 Antigen Profile

Protein Summary

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Gene names and symbols associated with ACAT1

  • acetyl-CoA acetyltransferase 1 (ACAT1) antibody
  • acetyl-CoA acetyltransferase 1 (Acat1) antibody
  • acetyl-CoA acetyltransferase 1 (acat1) antibody
  • acetyl-Coenzyme A acetyltransferase 1 (Acat1) antibody
  • acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (acat1) antibody
  • 6330585C21Rik antibody
  • Acat antibody
  • acat1-a antibody
  • fd16h07 antibody
  • fd20g06 antibody
  • MAT antibody
  • RATACAL antibody
  • T2 antibody
  • THIL antibody
  • wu:fd16h07 antibody
  • wu:fd20g06 antibody
  • zgc:86832 antibody

Protein level used designations for ACAT1

acetyl-CoA acetyltransferase 1 , acetoacetyl Coenzyme A thiolase , acetoacetyl-CoA thiolase , acetyl-CoA acetyltransferase, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 , mitochondrial acetoacetyl-CoA thiolase , acetyl-Co A acetyltransferase 1 mitochondrial , acetyl-coenzyme A acetyltransferase 1 , Acetoacetyl-CoA thiolase A , acetyl-CoA acetyltransferase A, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)

GENE ID SPECIES
100597123 Nomascus leucogenys
100626793 Sus scrofa
38 Homo sapiens
25014 Rattus norvegicus
414639 Xenopus laevis
418968 Gallus gallus
511082 Bos taurus
489421 Canis lupus familiaris
110446 Mus musculus
445290 Danio rerio
Selected quality suppliers for anti-ACAT1 (ACAT1) Antibodies
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