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anti-Acid Phosphatase, Prostate (ACPP) Antibodies

ACPP encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. Additionally we are shipping ACPP Proteins (22) and ACPP Kits (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACPP 58813  
ACPP 70881 Q91YE9
ACPP 55 P15309
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Top anti-ACPP Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ACPP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:6... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB PAP Antibody (Center) (ABIN655637) immunohistochemistry analysis in fo... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB AP20162PU-N ACPP Antibody staining of paraffin embedded Human Prostate... AP20162PU-N ACPP Antibody staining of Human Prostate lysate at 0.3 µg/... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACPP Antibody (C-term) (ABIN391855) in m... Formalin-fixed and paraffin-embedded human lung carcinoma tissue react... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue react... Western blot analysis of anti-ACPP Antibody (C-term) in mouse lung tis... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of MCF-7 cell line, using ACPP antib... 100 μL Log in to see 9 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB (0.3µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buf... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated cELISA, FACS FACS analysis of BOSC23 cells using LT-3D1. BOSC23 cells were transien... SDS-PAGE analysis of purified LT-3D1 monoclonalantibody. Lane 1: molec... 100 μg Log in to see 5 to 6 Days
$358.05
Details
Human Goat Un-conjugated EIA, IHC (p), WB AP31101PU-N ACPP antibody staining of paraffin embedded Human Prostate... AP31101PU-N ACPP antibody staining of Human Prostate lysate at 0.01 µg... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details

ACPP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Mouse (Murine) , , , ,
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Human , , , ,
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Top referenced anti-ACPP Antibodies

  1. Mouse (Murine) Polyclonal ACPP Primary Antibody for IHC, WB - ABIN3022672 : Ostanin, Saeed, Van Etten: Heterologous expression of human prostatic acid phosphatase and site-directed mutagenesis of the enzyme active site. in The Journal of biological chemistry 1994 (PubMed)
    Show all 4 references for ABIN3022672

  2. Human Monoclonal ACPP Primary Antibody for cELISA, FACS - ABIN238332 : Veeramani, Yuan, Chen, Lin, Petersen, Shaheduzzaman, Srivastava, MacDonald, Lin: Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer. in Endocrine-related cancer 2005 (PubMed)
    Show all 3 references for ABIN238332

  3. Human Polyclonal ACPP Primary Antibody for EIA, IHC (p) - ABIN359766 : Klyushnenkova, Kouiavskaia, Kodak, Vandenbark, Alexander: Identification of HLA-DRB1*1501-restricted T-cell epitopes from human prostatic acid phosphatase. in The Prostate 2007 (PubMed)
    Show all 3 references for ABIN359766

  4. Human Polyclonal ACPP Primary Antibody for IHC (p), WB - ABIN655637 : Dettwiler, Aringhieri, Cardinale, Keller, Barabino: Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN655637

  5. Human Polyclonal ACPP Primary Antibody for IHC (p), WB - ABIN391855 : Quintero, Araujo, Pulkka, Wirkkala, Herrala, Eskelinen, Jokitalo, Hellström, Tuominen, Hirvikoski, Vihko: Prostatic acid phosphatase is not a prostate specific target. in Cancer research 2007 (PubMed)

  6. Human Polyclonal ACPP Primary Antibody for ELISA, WB - ABIN570986 : Nousiainen, Quintero, Myöhänen, Voikar, Mijatovic, Segerstråle, Herrala, Kulesskaya, Pulkka, Kivinummi, Abo-Ramadan, Taira, Piepponen, Rauvala, Vihko: Mice deficient in transmembrane prostatic acid phosphatase display increased GABAergic transmission and neurological alterations. in PLoS ONE 2014 (PubMed)

More Antibodies against ACPP Interaction Partners

Pig (Porcine) Acid Phosphatase, Prostate (ACPP) interaction partners

  1. The obtained N-terminal amino-acid sequence of boar PTAP showed 92% identity with the N-terminal amino-acid sequence of human PAP (show PDAP1 Antibodies). The determined sequence of a 354 bp nucleotide fragment showed 90% identity with the corresponding sequence of human PAP (show PDAP1 Antibodies).

Mouse (Murine) Acid Phosphatase, Prostate (ACPP) interaction partners

  1. TMPAP is involved in the control of GABAergic tone in the brain also through exocytosis, and that PAP (show ASAP1 Antibodies) deficiency produces a distinct neurological phenotype.

  2. In male mouse saliva (show RAG1AP1 Antibodies) prostatic acid phosphatase regulates salivation.

  3. Data indicate that prostate acid phosphatase-based peptide vaccine PAP (show ASAP1 Antibodies)-114-128 peptide appears to be a relevant for the treatment of prostate cancer.

  4. this PAP (show ASAP1 Antibodies)-/- mouse model shows that TMPAP is required for the normal function of prostate in mice, and its deficiency leads to prostate adenocarcinoma.

  5. Both prostatic acid phosphatase and ecto-5'-nucleotidase generate adenosine in the dorsal spinal cord.

  6. Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.

  7. Experiments indicate that PAP (show ASAP1 Antibodies) and NT5E (show NT5E Antibodies) are the main ectonucleotidases that generate adenosine in nociceptive circuits and indicate these enzymes transform pulsatile or sustained nucleotide release into an inhibitory adenosinergic signal.

  8. prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 (show ERBB2 Antibodies) and regulates prostate cancer cell growth

  9. studies highlight similarities and differences in PAP (show ASAP1 Antibodies) localization within nociceptive neurons of mice and rats

  10. PAP (show ASAP1 Antibodies) has species-conserved antinociceptive effects and has pH-dependent ectonucleotidase activity

Human Acid Phosphatase, Prostate (ACPP) interaction partners

  1. Prostatic acid phosphatase delays prostate cancer cell growth in G1 phase of the cell cycle.

  2. Studies suggest that understanding of prostatic acid phosphatase function and regulation of expression will have a significant impact on understanding prostate cancer (PCa (show FLVCR1 Antibodies)) progression and therapy.

  3. Certain factors identified within semen, termed semen-derived enhancers of virus infection (SEVI), fragments of prostatic acid phosphatase, have been shown to significantly enhance HIV-1 infectivity.

  4. ACPP increases significantly in epithelial cells of ovarian carcinoma, which indicates that it may be a candidate biomarker for diagnosis of epithelia-derived ovarian cancer in women.

  5. Data indicate that hypoxia regulates prostatic acid phosphatase (PAP) through hypoxia-inducible factor 2 alpha (show EPAS1 Antibodies) (HIF2alpha (show EPAS1 Antibodies)) and from stimulated A2B (show ADORA2B Antibodies) adenosine receptors.

  6. GCNT1 (show GCNT1 Antibodies) is over-expressed in prostate cancer and is associated with higher levels of core 2 O-sLe(x) in PSA (show PLAG1 Antibodies), PAP (show REG3A Antibodies) and MUC1 (show MUC1 Antibodies) proteins.

  7. Data indicate that prostate acid phosphatase-based peptide vaccine PAP (show REG3A Antibodies)-114-128 peptide appears to be a relevant for the treatment of prostate cancer.

  8. Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1 (show ADA Antibodies)) activities in neonatal blood favor elevated extracellular adenosine.

  9. in the in vivo environment, PAP (show REG3A Antibodies)(248-286) is likely to form fibrils efficiently, thus providing an explanation for the presence of semen-derived enhancer of viral infection in human semen.

  10. Peptide fragments derived from N-proximal and C-proximal of the PAP (show REG3A Antibodies) form fibrillar structures and increase virion attachment to cells.

ACPP Antigen Profile

Protein Summary

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ACPP

  • acid phosphatase, prostate (ACPP) antibody
  • acid phosphatase, prostate (LOC100352974) antibody
  • prostatic acid phosphatase (CpipJ_CPIJ004002) antibody
  • prostatic acid phosphatase (CpipJ_CPIJ017646) antibody
  • prostatic acid phosphatase (Smp_016640) antibody
  • 5' nucleotidase, ecto (Nt5e) antibody
  • 5'-nucleotidase, cytosolic IB (Nt5c1b) antibody
  • acid phosphatase, prostate (Acpp) antibody
  • acid phosphatase, prostate (acpp) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2) antibody
  • 5'-NT antibody
  • 4921514H13Rik antibody
  • A030005E02Rik antibody
  • acp-3 antibody
  • acp3 antibody
  • ACPP antibody
  • Acpp11 antibody
  • acpt antibody
  • AIRP antibody
  • AMAP2 antibody
  • CD73 antibody
  • CENTB3 antibody
  • CN-IB antibody
  • DDEF2 antibody
  • FRAP antibody
  • Lap antibody
  • Nt5 antibody
  • PAG3 antibody
  • pap antibody
  • Pap-alpha antibody
  • Ppal antibody
  • RNACPP11 antibody
  • SHAG1 antibody

Protein level used designations for ACPP

prostatic acid phosphatase , acid phosphatase, prostate , tyrosine acid phosphatase , prostatic acid phosphatase-like , 5'-NT , 5'-nucleotidase , ecto-5'-nucleotidase , 5'nucleotidase , autoimmune infertility-related protein , cN1B , cytosolic 5'-nucleotidase 1B , cytosolic 5'-nucleotidase IB , TMPase , prostatic acid phosphotase , thiamine monophosphatase , fluoride-resistant acid phosphatase , lysosomal acid phosphatase , prostatic acid phosphatase (rPAP) , testicular acid phosphatase homolog , PYK2 C terminus-associated protein , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 , centaurin, beta 3 , development and differentiation enhancing factor 2 , development and differentiation-enhancing factor 2 , paxillin-associated protein with ARF GAP activity 3 , pyk2 C-terminus-associated protein

GENE ID SPECIES
460702 Pan troglodytes
717786 Macaca mulatta
776390 Gallus gallus
100302507 Sus scrofa
100352974 Oryctolagus cuniculus
100407634 Callithrix jacchus
100439440 Pongo abelii
6035387 Culex quinquefasciatus
6051825 Culex quinquefasciatus
8349859 Schistosoma mansoni
100590181 Nomascus leucogenys
58813 Rattus norvegicus
70881 Mus musculus
55 Homo sapiens
485662 Canis lupus familiaris
56318 Mus musculus
56780 Rattus norvegicus
504700 Bos taurus
446918 Xenopus laevis
8853 Homo sapiens
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