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anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) Antibodies

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Additionally we are shipping CD166 Kits (55) and CD166 Proteins (39) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALCAM 214 Q13740
ALCAM 11658 Q61490
ALCAM 79559 O35112
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Top anti-CD166 Antibodies at antibodies-online.com

Showing 10 out of 207 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD166 antibody (N-term) (ABIN389410) in NCI-H460 cell line lysates (35 µg/lane). CD166 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with CD166 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded striated muscle tissues using AlCAM mouse mAb with DAB staining. 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Lane 1: human colon carcinoma lysates Lane 2: rat brain lysates probed with Anti CD166 Polyclonal Antibody, Unconjugated (ABIN673944) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 64kD. Observed band size: 64kD. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IHC, ELISA Figure 1: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), kidney carcinoma (B), lung carcinoma (C) and breast carcinoma (D), showing cytoplasmic and membrane localization with DAB staining using ALCAM mouse mAb. 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse PE FACS Detection of ALCAM/CD166 in Human Whole Blood Lymphocytes by Flow Cytometry. Human whole blood lymphocytes were stained with Mouse Anti-Human ALCAM/CD166 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$367.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse Un-conjugated ELISA, IHC   100 μL Log in to see 10 to 11 Days
$428.57
Details
Human Mouse Un-conjugated ELISA, WB   100 μL Log in to see 10 to 11 Days
$428.57
Details

ALCAM Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CD166 Antibodies

  1. Human Monoclonal CD166 Primary Antibody for FACS - ABIN4897157 : Soh, Zheng, Li Yeo, Yang, Ng, Wong, Zhang, Li, Nichane, Asmat, Wong, Wong, Su, Mantalaris, Lu, Xian, McKeon, Chen, Lim, Lim: CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. in Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)
    Show all 6 references for ABIN4897157

  2. Human Monoclonal CD166 Primary Antibody for ELISA, IHC - ABIN2869324 : Kristiansen, Pilarsky, Wissmann, Stephan, Weissbach, Loy, Loening, Dietel, Rosenthal: ALCAM/CD166 is up-regulated in low-grade prostate cancer and progressively lost in high-grade lesions. in The Prostate 2002 (PubMed)
    Show all 5 references for ABIN2869324

  3. Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN968954 : Fujiwara, Tatsumi, Kosaka, Sato, Higuchi, Yoshioka, Maeda, Ueda, Fujii: Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166). in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 references for ABIN968954

  4. Human Monoclonal CD166 Primary Antibody for ELISA, WB - ABIN2869314 : Zimmerman, Nelissen, van Emst-de Vries, Willems, de Lange, Collard, van Leeuwen, Figdor: Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases. in Journal of cell science 2004 (PubMed)
    Show all 3 references for ABIN2869314

  5. Human Polyclonal CD166 Primary Antibody for FACS, IHC (p) - ABIN389410 : Kahlert, Weber, Mogler, Bergmann, Schirmacher, Kenngott, Matterne, Mollberg, Rahbari, Hinz, Koch, Aigner, Weitz: Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. in British journal of cancer 2009 (PubMed)
    Show all 2 references for ABIN389410

  6. Human Monoclonal CD166 Primary Antibody for FACS, IHC - ABIN1724867 : Rauch, Rosenkranz, Böhm, Meyer-Kirchrath, Hohlfeld, Schrör, Rauch: Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes. in Vascular pharmacology 2011 (PubMed)
    Show all 2 references for ABIN1724867

  7. Human Monoclonal CD166 Primary Antibody for ICC, FACS - ABIN1724851 : Liang, Huang, Jia, Wang: Activated leukocyte cell adhesion molecule expression is up-regulated in the development of endometrioid carcinoma. in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2011 (PubMed)
    Show all 2 references for ABIN1724851

  8. Human Polyclonal CD166 Primary Antibody for FACS, IF (p) - ABIN673944 : Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014 (PubMed)

More Antibodies against CD166 Interaction Partners

Zebrafish Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Alcama mediates Edn1 (show EDN1 Antibodies) signaling during zebrafish cartilage morphogenesis.

Xenopus laevis Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. The cell-adhesion molecule (show MCAM Antibodies) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (show FZD3 Antibodies) during embryonic kidney development.

Atlantic Salmon (Salmo salar) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. No significant association between ALCAM expression and survival data was observed for all tumors

Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. SFMSCs increased through upregulation of the activated lymphocyte cell adhesion molecule (show MCAM Antibodies) (ALCAM) and N-cadherin (show CDH2 Antibodies) by microRNA-192 and -218 downregulation, similar to BMMSCs and ADMSCs.

  2. Analysis of KRAS mutation combined with immunohistochemical expression of CD44 (show CD44 Antibodies) and CD166 identified subgroups of patients with colon adenocarcinoma at higher risk of lymph node involvement by the tumor and development of liver and lung metastasis.

  3. Weak ALCAM expression was significantly correlated with established markers for poor prognosis, as well as shorter RFS and OS. ALCAM might be considered as a prognostic marker for infantile neuroblastoma (show ARHGEF16 Antibodies)

  4. CD166 antigen is specifically expressed on corneal endothelial cells.

  5. Prognostic Significance of CD44v6, CD133, CD166, and ALDH1 (show ALDH1A1 Antibodies) Expression in Small Intestinal Adenocarcinoma.

  6. The binding sites on CD6 (show CD6 Antibodies) and CD166 have been characterized to show that a SNP in CD6 (show CD6 Antibodies) causes glycosylation that hinders the CD6 (show CD6 Antibodies)/CD166 interaction.

  7. a model that CD166 regulates MCAM (show MCAM Antibodies) through a signaling flow from activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and c-Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signaling to the inhibition of potential MCAM (show MCAM Antibodies) ubiquitin E3 ligases, betaTrCP (show BTRC Antibodies) and Smurf1 (show SMURF1 Antibodies)

  8. High ALCAM expression in melanoma cells of the primary tumor may indicate a more invasive phenotype. Low expression of ALCAM in regional lymph node metastases is a feature associated with unfavorable prognosis in patients with cutaneous melanoma.

  9. High ALCAM expression is associated with Invasive Cholangiocarcinoma.

  10. The Serum CD166 is a novel diagnostic tumor marker for hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

Mouse (Murine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers

  2. Data indicate that the CD166/AKT (show AKT1 Antibodies) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (show FOXO3 Antibodies) proteins in liver cancer cells.

  3. ALCAM stably interacts with actin by binding to syntenin-1 (show SDCBP Antibodies) and ezrin (show EZR Antibodies).

  4. CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (show AGER Antibodies); it shows that binding of S100B (show S100B Antibodies) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (show NFKB1 Antibodies) family members in wild type and RAGE (show AGER Antibodies)-deficient mouse endothelial cells.

  5. Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (show RUNX2 Antibodies) expression and high hematopoiesis enhancing activity.

  6. Behavioral deficits caused by prolonged IFN alpha (show IFNA Antibodies) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.

  7. novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.

  8. The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.

  9. CD166 is highly expressed within the endogenous intestinal stem cell niche

  10. The higher adhesion molecules expression and higher BBB (show ALMS1 Antibodies) permeability contributed to the major inflammatory cell infiltration into the CNS of C57BL/6 mice that was not efficient to control the parasite.

Pig (Porcine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.

CD166 (ALCAM) Antigen Profile

Protein Summary

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene names and symbols associated with ALCAM

  • activated leukocyte cell adhesion molecule a (alcama) antibody
  • activated leukocyte cell adhesion molecule (alcam) antibody
  • activated leukocyte cell adhesion molecule (ALCAM) antibody
  • CD166 antigen homolog (cd166) antibody
  • activated leukocyte cell adhesion molecule (Alcam) antibody
  • AI853494 antibody
  • ALCAM antibody
  • BEN antibody
  • CD166 antibody
  • DM-GRASP antibody
  • JC7 antibody
  • MEMD antibody
  • MuSC antibody
  • SC1 antibody

Protein level used designations for ALCAM

CD166 antigen homolog A , DM-GRASP homolog , neurolin , neurolin-a , zn5 / zn-5 antigen , zn8 / zn-8 antigen , activated leukocyte cell adhesion molecule , CD166 antigen , DM-GRASP II , CD166 antigen-like , CD166 antigen homolog , HB2 , KG-CAM , SB-10 antigen , activated leucocyte cell adhesion molecule , BEN glycoprotein , SC1 glycoprotein

GENE ID SPECIES
30194 Danio rerio
444425 Xenopus laevis
460565 Pan troglodytes
703777 Macaca mulatta
780210 Xenopus (Silurana) tropicalis
100061848 Equus caballus
100173616 Pongo abelii
100473255 Ailuropoda melanoleuca
100286453 Salmo salar
100015168 Monodelphis domestica
100598547 Nomascus leucogenys
214 Homo sapiens
11658 Mus musculus
79559 Rattus norvegicus
281614 Bos taurus
396092 Gallus gallus
100009305 Oryctolagus cuniculus
478550 Canis lupus familiaris
397269 Sus scrofa
100726386 Cavia porcellus
101114151 Ovis aries
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