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ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Additionally we are shipping CD166 Kits (62) and CD166 Proteins (37) and many more products for this protein.
Showing 10 out of 191 products:
Human Monoclonal CD166 Primary Antibody for Func, FACS - ABIN610440
Bennett, Calakos, Scheller: Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. in Science (New York, N.Y.) 1992
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Human Monoclonal CD166 Primary Antibody for IHC - ABIN2869324
Kristiansen, Pilarsky, Wissmann, Stephan, Weissbach, Loy, Loening, Dietel, Rosenthal: ALCAM/CD166 is up-regulated in low-grade prostate cancer and progressively lost in high-grade lesions. in The Prostate 2002
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Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN968954
Fujiwara, Tatsumi, Kosaka, Sato, Higuchi, Yoshioka, Maeda, Ueda, Fujii: Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166). in The Journal of clinical endocrinology and metabolism 2003
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Human Monoclonal CD166 Primary Antibody for IHC (fro), WB - ABIN1105934
Bruder, Ricalton, Boynton, Connolly, Jaiswal, Zaia, Barry: Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998
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Human Monoclonal CD166 Primary Antibody for ELISA, WB - ABIN1724709
Zimmerman, Nelissen, van Emst-de Vries, Willems, de Lange, Collard, van Leeuwen, Figdor: Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases. in Journal of cell science 2004
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Human Monoclonal CD166 Primary Antibody for FACS, IHC - ABIN1724867
Rauch, Rosenkranz, Böhm, Meyer-Kirchrath, Hohlfeld, Schrör, Rauch: Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes. in Vascular pharmacology 2011
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Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN1098107
Liang, Huang, Jia, Wang: Activated leukocyte cell adhesion molecule expression is up-regulated in the development of endometrioid carcinoma. in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2011
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Human Polyclonal CD166 Primary Antibody for FACS, IHC (p) - ABIN389410
Kahlert, Weber, Mogler, Bergmann, Schirmacher, Kenngott, Matterne, Mollberg, Rahbari, Hinz, Koch, Aigner, Weitz: Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. in British journal of cancer 2009
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Human Polyclonal CD166 Primary Antibody for IF (p), IHC (p) - ABIN673944
Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014
Alcama mediates Edn1 (show EDN1 Antibodies) signaling during zebrafish cartilage morphogenesis.
The cell-adhesion molecule (show MCAM Antibodies) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (show FZD3 Antibodies) during embryonic kidney development.
No significant association between ALCAM expression and survival data was observed for all tumors
Prognostic Significance of CD44v6, CD133, CD166, and ALDH1 (show ALDH1A1 Antibodies) Expression in Small Intestinal Adenocarcinoma.
The binding sites on CD6 (show CD6 Antibodies) and CD166 have been characterized to show that a SNP in CD6 (show CD6 Antibodies) causes glycosylation that hinders the CD6 (show CD6 Antibodies)/CD166 interaction.
a model that CD166 regulates MCAM (show MCAM Antibodies) through a signaling flow from activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and c-Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signaling to the inhibition of potential MCAM (show MCAM Antibodies) ubiquitin E3 ligases, betaTrCP (show BTRC Antibodies) and Smurf1 (show SMURF1 Antibodies)
High ALCAM expression in melanoma cells of the primary tumor may indicate a more invasive phenotype. Low expression of ALCAM in regional lymph node metastases is a feature associated with unfavorable prognosis in patients with cutaneous melanoma.
High ALCAM expression is associated with Invasive Cholangiocarcinoma.
The Serum CD166 is a novel diagnostic tumor marker for hepatocellular carcinoma (HCC (show FAM126A Antibodies)).
Overexpression of activated leukocute cell adhesion molecule (show MCAM Antibodies) in gastric cancer is associated with advanced stages and poor prognosis and miR (show MLXIP Antibodies)-9 deregulation
Differentially expressed/regulated cancer-related genes upon miR (show MLXIP Antibodies)-125b expression along with the significant increase of ALCAM
Low expression of ALCAM at sites of cell-cell contact in primary breast cancer tumors regardless of differentiation, size and lymph node involvement may contribute to the more aggressive phenotype of breast cancer among African-American women.
an overexpression of CD166 was detected in the benign and malignant salivary gland tumors and its expression in the malignant tumor was associated with the aggressive behavior and tumor progression.
Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers
Data indicate that the CD166/AKT (show AKT1 Antibodies) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (show FOXO3 Antibodies) proteins in liver cancer cells.
ALCAM stably interacts with actin by binding to syntenin-1 (show SDCBP Antibodies) and ezrin (show EZR Antibodies).
CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (show AGER Antibodies); it shows that binding of S100B (show S100B Antibodies) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (show NFKB1 Antibodies) family members in wild type and RAGE (show AGER Antibodies)-deficient mouse endothelial cells.
Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (show RUNX2 Antibodies) expression and high hematopoiesis enhancing activity.
Behavioral deficits caused by prolonged IFN alpha (show IFNA Antibodies) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.
novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.
The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.
CD166 is highly expressed within the endogenous intestinal stem cell niche
The higher adhesion molecules expression and higher BBB (show ALMS1 Antibodies) permeability contributed to the major inflammatory cell infiltration into the CNS of C57BL/6 mice that was not efficient to control the parasite.
ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
CD166 antigen homolog A
, DM-GRASP homolog
, zn5 / zn-5 antigen
, zn8 / zn-8 antigen
, activated leukocyte cell adhesion molecule
, CD166 antigen
, DM-GRASP II
, CD166 antigen-like
, CD166 antigen homolog
, SB-10 antigen
, activated leucocyte cell adhesion molecule
, BEN glycoprotein
, SC1 glycoprotein