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anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) Antibodies

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Additionally we are shipping CD166 Kits (61) and CD166 Proteins (37) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALCAM 214 Q13740
ALCAM 11658 Q61490
ALCAM 79559 O35112
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Top anti-CD166 Antibodies at antibodies-online.com

Showing 10 out of 177 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD166 antibody (N-term) (ABIN389410) in NCI-H... Formalin-fixed and paraffin-embedded human brain tissue reacted with C... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: human colon carcinoma lysates Lane 2: rat brain lysates probed... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Immunohistochemical analysis of paraffin-embedded striated m... 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA Figure 1: Immunohistochemical analysis of paraffin-embedded human ovar... 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse Un-conjugated IHC (fro), WB   1 mL Log in to see 6 to 8 Days
$489.50
Details
Human Mouse FITC FACS Profile of anti-ALCAM (CD166) reactivity on Jurkat cells analyzed by f... 50 Tests Log in to see 16 Days
$198.00
Details
Human Mouse PE FACS Profile of anti-ALCAM (CD166) reactivity on Jurkat cells analyzed by f... 50 Tests Log in to see 16 Days
$198.00
Details

ALCAM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,

Top referenced anti-CD166 Antibodies

  1. Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN968954 : Fujiwara, Tatsumi, Kosaka, Sato, Higuchi, Yoshioka, Maeda, Ueda, Fujii: Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166). in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 references for ABIN968954

  2. Human Monoclonal CD166 Primary Antibody for IHC (fro), WB - ABIN1105934 : Bruder, Ricalton, Boynton, Connolly, Jaiswal, Zaia, Barry: Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998 (PubMed)
    Show all 3 references for ABIN1105934

  3. Human Polyclonal CD166 Primary Antibody for FACS, IHC (p) - ABIN389410 : Kahlert, Weber, Mogler, Bergmann, Schirmacher, Kenngott, Matterne, Mollberg, Rahbari, Hinz, Koch, Aigner, Weitz: Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. in British journal of cancer 2009 (PubMed)
    Show all 2 references for ABIN389410

  4. Human Monoclonal CD166 Primary Antibody for ELISA, WB - ABIN1724709 : Zimmerman, Nelissen, van Emst-de Vries, Willems, de Lange, Collard, van Leeuwen, Figdor: Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases. in Journal of cell science 2004 (PubMed)
    Show all 2 references for ABIN1724709

  5. Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN1098107 : Rauch, Rosenkranz, Böhm, Meyer-Kirchrath, Hohlfeld, Schrör, Rauch: Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes. in Vascular pharmacology 2011 (PubMed)
    Show all 2 references for ABIN1098107

  6. Human Monoclonal CD166 Primary Antibody for ICC, FACS - ABIN1724851 : Liang, Huang, Jia, Wang: Activated leukocyte cell adhesion molecule expression is up-regulated in the development of endometrioid carcinoma. in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2011 (PubMed)
    Show all 2 references for ABIN1724851

  7. Human Polyclonal CD166 Primary Antibody for IF (p), IHC (p) - ABIN673944 : Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014 (PubMed)

More Antibodies against CD166 Interaction Partners

Zebrafish Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Alcama mediates Edn1 (show EDN1 Antibodies) signaling during zebrafish cartilage morphogenesis.

Xenopus laevis Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. The cell-adhesion molecule (show MCAM Antibodies) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (show FZD3 Antibodies) during embryonic kidney development.

Atlantic Salmon (Salmo salar) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. No significant association between ALCAM expression and survival data was observed for all tumors

Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. The binding sites on CD6 (show CD6 Antibodies) and CD166 have been characterized to show that a SNP in CD6 (show CD6 Antibodies) causes glycosylation that hinders the CD6 (show CD6 Antibodies)/CD166 interaction.

  2. a model that CD166 regulates MCAM (show MCAM Antibodies) through a signaling flow from activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and c-Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signaling to the inhibition of potential MCAM (show MCAM Antibodies) ubiquitin E3 ligases, betaTrCP (show BTRC Antibodies) and Smurf1 (show SMURF1 Antibodies)

  3. High ALCAM expression in melanoma cells of the primary tumor may indicate a more invasive phenotype. Low expression of ALCAM in regional lymph node metastases is a feature associated with unfavorable prognosis in patients with cutaneous melanoma.

  4. High ALCAM expression is associated with Invasive Cholangiocarcinoma.

  5. The Serum CD166 is a novel diagnostic tumor marker for hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

  6. Overexpression of activated leukocute cell adhesion molecule (show MCAM Antibodies) in gastric cancer is associated with advanced stages and poor prognosis and miR (show MLXIP Antibodies)-9 deregulation

  7. Differentially expressed/regulated cancer-related genes upon miR (show MLXIP Antibodies)-125b expression along with the significant increase of ALCAM

  8. Low expression of ALCAM at sites of cell-cell contact in primary breast cancer tumors regardless of differentiation, size and lymph node involvement may contribute to the more aggressive phenotype of breast cancer among African-American women.

  9. an overexpression of CD166 was detected in the benign and malignant salivary gland tumors and its expression in the malignant tumor was associated with the aggressive behavior and tumor progression.

  10. ALCAM is generally expressed in normal and cancerous breast epithelium and that a marked reduction of ALCAM expression characterizes a subset of breast cancer patients with adverse tumor characteristics and unfavorable clinical outcome.

Mouse (Murine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers

  2. Data indicate that the CD166/AKT (show AKT1 Antibodies) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (show FOXO3 Antibodies) proteins in liver cancer cells.

  3. ALCAM stably interacts with actin by binding to syntenin-1 (show SDCBP Antibodies) and ezrin (show EZR Antibodies).

  4. CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (show AGER Antibodies); it shows that binding of S100B (show S100B Antibodies) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (show NFKB1 Antibodies) family members in wild type and RAGE (show AGER Antibodies)-deficient mouse endothelial cells.

  5. Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (show RUNX2 Antibodies) expression and high hematopoiesis enhancing activity.

  6. Behavioral deficits caused by prolonged IFN alpha (show IFNA Antibodies) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.

  7. novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.

  8. The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.

  9. CD166 is highly expressed within the endogenous intestinal stem cell niche

  10. The higher adhesion molecules expression and higher BBB (show ALMS1 Antibodies) permeability contributed to the major inflammatory cell infiltration into the CNS of C57BL/6 mice that was not efficient to control the parasite.

Pig (Porcine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.

CD166 (ALCAM) Antigen Profile

Protein Summary

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene names and symbols associated with ALCAM

  • activated leukocyte cell adhesion molecule a (alcama) antibody
  • activated leukocyte cell adhesion molecule (alcam) antibody
  • activated leukocyte cell adhesion molecule (ALCAM) antibody
  • CD166 antigen homolog (cd166) antibody
  • activated leukocyte cell adhesion molecule (Alcam) antibody
  • AI853494 antibody
  • ALCAM antibody
  • BEN antibody
  • CD166 antibody
  • DM-GRASP antibody
  • JC7 antibody
  • MEMD antibody
  • MuSC antibody
  • SC1 antibody

Protein level used designations for ALCAM

CD166 antigen homolog A , DM-GRASP homolog , neurolin , neurolin-a , zn5 / zn-5 antigen , zn8 / zn-8 antigen , activated leukocyte cell adhesion molecule , CD166 antigen , DM-GRASP II , CD166 antigen-like , CD166 antigen homolog , HB2 , KG-CAM , SB-10 antigen , activated leucocyte cell adhesion molecule , BEN glycoprotein , SC1 glycoprotein

GENE ID SPECIES
30194 Danio rerio
444425 Xenopus laevis
460565 Pan troglodytes
703777 Macaca mulatta
780210 Xenopus (Silurana) tropicalis
100061848 Equus caballus
100173616 Pongo abelii
100473255 Ailuropoda melanoleuca
100286453 Salmo salar
100015168 Monodelphis domestica
100598547 Nomascus leucogenys
214 Homo sapiens
11658 Mus musculus
79559 Rattus norvegicus
281614 Bos taurus
396092 Gallus gallus
100009305 Oryctolagus cuniculus
478550 Canis lupus familiaris
397269 Sus scrofa
100726386 Cavia porcellus
101114151 Ovis aries
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