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anti-Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Antibodies

AP3B1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Additionally we are shipping AP3B1 Kits (9) and AP3B1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AP3B1 8546 O00203
AP3B1 11774 Q9Z1T1
AP3B1 309969  
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Top anti-AP3B1 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p) Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AP3B1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB The AP3 Antibody is used in Western blot to detect AP3 in HeLa cell lysates. 0.1 mg Log in to see 2 to 6 Days
$359.70
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AP3B1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Ap3b1 antibody used at 2.5 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   0.1 mL Log in to see 5 to 7 Days
$452.81
Details
Human Goat Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

AP3B1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
, ,
,
Mouse (Murine)


Rat (Rattus)


More Antibodies against AP3B1 Interaction Partners

Human Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. Synergistic defects of UNC13D (show UNC13D Antibodies) and AP3B1 leading to adult hemophagocytic lymphohistiocytosis.

  2. Using a co-affinity purification strategy, authors have identified the beta subunit (show POLG Antibodies) of the AP-3 adapter protein (show TOLLIP Antibodies) complex, AP3B1, as a binding partner for the M proteins of the zoonotic paramyxoviruses Nipah virus and Hendra virus.

  3. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1 (show RUFY1 Antibodies)) interacts specifically and directly with adaptor protein complex AP-3.

  4. The study provides a description of two unrelated individuals with Hermansky Pudlak syndrome type 2 associated with novel mutations in AP3B1.

  5. diphosphoinositol pentakisphosphate-mediated pyrophosphorylation of AP3B1 modulates the interaction with Kif3A (show KIF3A Antibodies) and, as a consequence, affects the release of HIV-1 virus-like particles.

  6. Two nonsense mutations in ADTB3A, C1578T (R-->X) and G2028T (E-->X), result in lack of ADTB3A mRNA and beta3A (show BHLHE22 Antibodies) protein production and a severe, G-CSF (show CSF3 Antibodies)-responsive neutropenia in addition to oculocutaneous albinism and platelet storage pool deficiency.

  7. Description of mutations in HPS (show HPS1 Antibodies) genes that cause Hermansky-Pudlak syndrome (review)

  8. We defined a homozygous genomic deletion in AP3B1, the gene encoding the beta chain of the adaptor protein-3 (AP-3) complex. The mutation leads to in-frame skipping of exon 15 and thus perturbs proper assembly of the heterotetrameric AP-3 complex.

  9. A novel homozygous mutation in AP3B1 was detected in a 2-year-old patient with oculocutaneous albinism and immunodeficiency with Hermansky-Pudlak syndrome type II and eventual acute fatal hemophagocytic lymphohistiocytosis.

  10. Mutations in AP3B1 is not associated with familial hemophagocytic lymphohistiocytosis

Mouse (Murine) Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. Data show that cytokine activation as a result of toll-like receptor 2 (TLR2 (show TLR2 Antibodies)) stimulation occurs at different intracellular locations and is mediated by the phagosomal trafficking molecule adaptor protein-3 (show HSPB3 Antibodies) (AP-3).

  2. Our study indicates that Ap3b1 gene play distinct roles in melanin production and tyrosinase (show TYR Antibodies) distribution compared with Hps1 gene.

  3. we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

  4. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  5. The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 (show PLDN Antibodies) and BLOC-2 (show HPS6 Antibodies) are essential for plasmacytoid dendritic cells signaling through TLR7 (show TLR7 Antibodies) and TLR9 (show TLR9 Antibodies).

  6. TLR9 (show TLR9 Antibodies) signals leading to activation of IFN I, require TLR9 (show TLR9 Antibodies) trafficking from endosomes to lysosome-related organelle; adapter protein (show GRB10 Antibodies)-3 (show HSPB3 Antibodies) identified as protein complex responsible for trafficking of TLR9 (show TLR9 Antibodies) to this subcellular compartment

  7. AP-3 mediates the intracellular trafficking of CD1d (show CD1D Antibodies) to lysosomes for sampling of lipid antigens (Ags (show GLA Antibodies)) involved in self-Ag presentation and thymocyte-positive selection.

  8. AP-3 requirement is a particular attribute of the CD1d (show CD1D Antibodies) pathway in mice and that, although MHC class II molecules and CD1d (show CD1D Antibodies) are both found in late endosomes or lysosomes, different pathways mediate their intracellular trafficking

  9. AP-3B (show AP3M2 Antibodies) plays a critical role in the normal formation and function of a subset of synaptic vesicles

  10. the functions of beta3A- and beta3B (show AP3B2 Antibodies)-containing complexes are distinct and divergent in brain

AP3B1 Antigen Profile

Protein Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AP3B1

  • adaptor-related protein complex 3, beta 1 subunit (ap3b1) antibody
  • adaptor-related protein complex 3, beta 1 subunit (AP3B1) antibody
  • adaptor-related protein complex 3, beta 1 subunit (LOC100350054) antibody
  • adaptor-related protein complex 3, beta 1 subunit (Ap3b1) antibody
  • ADTB3 antibody
  • ADTB3A antibody
  • AP-3 antibody
  • AP3B1 antibody
  • AU015684 antibody
  • beta3A antibody
  • C78395 antibody
  • cb964 antibody
  • HPS antibody
  • Hps2 antibody
  • pe antibody
  • pearl antibody
  • rim2 antibody

Protein level used designations for AP3B1

adaptor-related protein complex 3, beta 1 subunit , AP-3 complex subunit beta-1 , adaptor-related protein complex 3, beta-1 subunit , AP-3 complex subunit beta-1-like , AP-3 complex beta-3A subunit , adaptor protein complex AP-3 subunit beta-1 , beta-3A-adaptin , clathrin assembly protein complex 3 beta-1 large chain , adapter-related protein complex 3 subunit beta-1 , adaptor protein complex AP-3 beta-1 subunit , adaptor-related protein complex AP-3, beta 1 subunit , beta3A-adaptin , recombination induced mutation 2 , adaptor-related protein complex AP3 beta 1 subunit

GENE ID SPECIES
443724 Xenopus laevis
386770 Danio rerio
427646 Gallus gallus
461789 Pan troglodytes
100019944 Monodelphis domestica
100049670 Sus scrofa
100065436 Equus caballus
100226392 Taeniopygia guttata
100350054 Oryctolagus cuniculus
100397094 Callithrix jacchus
100584809 Nomascus leucogenys
708754 Macaca mulatta
8546 Homo sapiens
11774 Mus musculus
309969 Rattus norvegicus
767602 Bos taurus
403459 Canis lupus familiaris
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