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Adenosine Deaminase Proteins (ADA)

ADA encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Additionally we are shipping ADA Antibodies (148) and ADA Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADA 100 P00813
ADA 11486 P03958
ADA 24165 Q920P6
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Top ADA Proteins at

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
HOST_Baculovirus infected Insect Cells Human His tag 10 μg Log in to see 16 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days

ADA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced ADA Proteins

  1. Human ADA Protein expressed in Escherichia coli (E. coli) - ABIN667926 : Daddona, Shewach, Kelley, Argos, Markham, Orkin: Human adenosine deaminase. cDNA and complete primary amino acid sequence. in The Journal of biological chemistry 1984 (PubMed)
    Show all 2 references for ABIN667926

More Proteins for Adenosine Deaminase (ADA) Interaction Partners

Fruit Fly (Drosophila melanogaster) Adenosine Deaminase (ADA) interaction partners

  1. The effects of increased adenosine in vivo by mutating the main Drosophila adenosine deaminase-related growth factor (ADGF-A), was studied.

  2. findings show that a null mutation in ADGF-A leads to dramatically increased levels of adenosine & deoxyadenosine in the larval hemolymph; this increase leads to larval death associated with the disintegration of fat body & development of melanotic tumors

Cow (Bovine) Adenosine Deaminase (ADA) interaction partners

  1. Crystal structure of CD26/dipeptidyl-peptidase IV (show DPP4 Proteins) in complex with adenosine deaminase

  2. the transition-state structures of PfADA, HsADA, and bovine ADA (BtADA) solved using competitive kinetic isotope effects (KIE) and density functional calculations

  3. This is the first report that an inhibitor molecule (EHNA) with a nucleoside framework binds to the open form of ADA and the first observation of conformational change of ADA in the crystalline state.

  4. Data demonstrate that dipeptidyl peptidase II (show DPP7 Proteins) can form a complex with adenosine deaminase, but with one order of magnitude higher dissociation constant than that of DPPIV (show DPP4 Proteins).

Human Adenosine Deaminase (ADA) interaction partners

  1. association between the occurrence of polycystic ovary syndrome with altered ADA activity and genetic distribution of G22A and A4223C polymorphisms of the ADA1 (show TADA1 Proteins) gene

  2. High level of ADA is associated with obesity.

  3. diagnostic value of serum adenosine deaminase (ADA) activity as a useful tool to differentiate HIV mono- and co-infection, was investigated.

  4. Platelet aggregation and adenosine deaminase (ADA) activity were evaluated in pregnant women living with some disease conditions including hypertension, diabetes mellitus and human immunodeficiency virus infection.

  5. Increase in serum ADA levels was observed in Oral Squamous Cell Carcinoma.

  6. This study aimed to investigate the activities of purinergic system ecto (show TRIM33 Proteins)-enzymes present on the platelet surface as well as CD39 (show ENTPD1 Proteins) and CD73 expressions on platelets of sickle cell anemia treated patients.

  7. Genetic variability within the ADA gene may influence adenosine concentration and in turn the immune response by lymphocytes in solid tumors.

  8. We conclude that pleural ADA activity could be integrated in the diagnostic procedures of pTB (show PTBP1 Proteins) in low to medium tuberculosis prevalence settings.

  9. ADA and ADK (show ADK Proteins) are involved in glioma progression; increased ADA and ADK (show ADK Proteins) levels in peritumoral tissues may be associated with epilepsy in glioma patients.

  10. In autologous cocultures of T cells with HIV-1-pulsed dendritic cells, adenosine deaminase decreased HIV-1-induced CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(hi) FOXP3 (show FOXP3 Proteins)(+) cells and enhanced the HIV-1-specific CD4 (show CD4 Proteins)(+) responder T cells.

Mouse (Murine) Adenosine Deaminase (ADA) interaction partners

  1. Pulmonary alveolar proteinosis in adenosine deaminase-deficient mice

  2. Dietary regulation of adenosine deaminase activity in stomach, small intestine and spleen of mice

  3. Data indicate that untreated murine adenosine deaminase ADA(-/-) Tregs show alterations in the plasma membrane CD39 (show ENTPD1 Proteins)/CD73. ectonucleotidase machinery and limited suppressive activity via extracellular adenosine.

  4. ADA is upregulated in NOD dendritic cells, which results in their exuberant and spontaneous activation, which triggers autoimmune T cell activation.

  5. The catalytic mechanism of Mus (show TRPV6 Proteins) musculus adenosine deaminase (ADA) has been studied by quantum mechanics and two-layered ONIOM calculations

  6. Adenosine deaminase is necessary but not sufficient to confer puromycin aminonucleoside sensitivity to podocytes.

  7. adenosine deaminase deficient results in deoxy-ATP accumulation and leads to reduced thymic T cell production

  8. Transactivation by a duodenum-specific enhancer requires functional GATA4 (show GATA4 Proteins) binding sites

  9. ADA-deficient B cells exhibit a higher propensity to undergo B cell receptor-mediated apoptosis than their wild-type counterparts, and suggest a role for ADA in the survival of cells during antigen-dependent responses.

  10. This study provides a basis for investigating the folding kinetics of murine ADA and folding mechanisms of (beta/alpha)8-barrel proteins using 19F NMR sepctroscopy.

Rabbit Adenosine Deaminase (ADA) interaction partners

  1. after the immunotherapy, the rabbits showed an increase in the E-ADA activity when compared with control (78.62%), contributing for the change in the immune response.

ADA Protein Profile

Protein Summary

This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Gene names and symbols associated with Adenosine Deaminase Proteins (ADA)

  • adenosine deaminase (ADA)
  • Adenosine deaminase (Ada)
  • Adenosine deaminase-related growth factor A (Adgf-A)
  • adenosine deaminase (ada)
  • adenosine deaminase (Ada)
  • ADA protein
  • ADA-like protein
  • ADGDF-A protein
  • adgf-a protein
  • adgfa protein
  • CG5992 protein
  • CG11994 protein
  • dADA protein
  • Dmel\\CG5992 protein
  • Dmel\\CG11994 protein
  • DrosADA protein
  • xada protein
  • zgc:92028 protein

Protein level used designations for Adenosine Deaminase Proteins (ADA)

Ada-PA , CG11994-PA , adenosine deaminase , Adgf-A-PA , Adgf-A-PB , CG5992-PA , CG5992-PB , adenosine deaminase-related growth factor A , adenosine aminohydrolase , ada1

100070773 Equus caballus
41092 Drosophila melanogaster
39976 Drosophila melanogaster
280712 Bos taurus
100 Homo sapiens
444167 Xenopus laevis
11486 Mus musculus
24165 Rattus norvegicus
100625920 Sus scrofa
100346236 Oryctolagus cuniculus
419194 Gallus gallus
477236 Canis lupus familiaris
436919 Danio rerio
Selected quality suppliers for ADA Proteins (ADA)
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