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anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Antibodies

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Additionally we are shipping ADRBK2 Proteins (6) and ADRBK2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADRBK2 320129 Q3UYH7
ADRBK2 157 P35626
ADRBK2 25372 P26819
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Top anti-ADRBK2 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ADRBK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/HeLa cells, using GRK3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB The anti-GRK3 Pab (ABIN390986) is used in Western blot to detect GRK3 in SK-OV-3 cell lysate (Lane 1) and mouse heart tissue lysate (Lane 2). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB The anti-GRK3 Pab is used in Western blot to detect GRK3 in SK-OV-3 cell lysate (Lane 1) and mouse heart tissue lysate (Lane 2). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with ADRBK2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of ADRBK2 (arrow) using rabbit polyclonal ADRBK2 Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Observed bind size: 80KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ADRBK2 (arrow) using rabbit polyclonal ADRBK2 Antibody (N-term) (ABIN653036). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK2 gene (Lane 2) . Formalin-fixed and paraffin-embedded human brain tissue reacted with ADRBK2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using GRK3, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Western blot (WB) analysis of GRK 3 antibody in extracts from HepG2 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

ADRBK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADRBK2 Antibodies

  1. Human Polyclonal ADRBK2 Primary Antibody for WB - ABIN390986 : Rao, Rapoport, Kim: Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients. in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009 (PubMed)
    Show all 4 references for ABIN390986

  2. Human Polyclonal ADRBK2 Primary Antibody for EIA, WB - ABIN359044 : Calabrese, Sallese, Stornaiuolo, Stuppia, Palka, De Blasi: Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes. in Genomics 1995 (PubMed)
    Show all 2 references for ABIN359044

  3. Human Polyclonal ADRBK2 Primary Antibody for EIA, IHC (p) - ABIN950649 : Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya, Valero, Vilella, Estivill, Carracedo,: Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009 (PubMed)
    Show all 2 references for ABIN950649

  4. Human Polyclonal ADRBK2 Primary Antibody for ELISA, WB - ABIN1533711 : Dunham, Shimizu, Roe, Chissoe, Hunt, Collins, Bruskiewich, Beare, Clamp, Smink, Ainscough, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beasley, Bird, Blakey, Bridgeman, Buck, Burgess, Burrill et al.: The DNA sequence of human chromosome 22. ... in Nature 1999 (PubMed)

  5. Chicken Polyclonal ADRBK2 Primary Antibody for WB - ABIN2784754 : Balabanian, Levoye, Klemm, Lagane, Hermine, Harriague, Baleux, Arenzana-Seisdedos, Bachelerie: Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling. in The Journal of clinical investigation 2008 (PubMed)

More Antibodies against ADRBK2 Interaction Partners

Mouse (Murine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

  1. GRK3 controls cardiac alpha1-adrenergic receptor responsiveness

Human Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

  1. effects of GRK3 modulation appear to be specific to chemokine (show CCL1 Antibodies)-mediated migration behaviors without influencing tumor cell proliferation or survival

  2. data are consistent with the possibility that oncogenes can induce cellular stiffness via an HDAC6 (show HDAC6 Antibodies)-induced reorganization of the vimentin (show VIM Antibodies) intermediate filament network

  3. Data indicate that CXCL12 (show CXCL12 Antibodies)-induced phosphorylation at CXCR4 (show CXCR4 Antibodies) S346/347 was mediated by GRK2/3.

  4. In oral squamous cell carcinomas, malignant cells and surrounding tissue overexpress the ADRBK2 gene.

  5. A reduced cortical concentration of GRK3 in schizophrenia (resembling that in aging) may result in altered G protein-dependent signaling, thus contributing to prefrontal deficits in schizophrenia.

  6. GRK3 is a negative regulator of cell growth whose expression is preferentially reduced in glioblastoma of the classical subtype as a consequence of activity in primary gliomagenic pathways.

  7. mRNA levels for GRK3 were inversely correlated with systolic and diastolic blood pressure (day, night and 24 h), which suggests a protective role for GRK3 in the regulation of human blood pressure

  8. we found no evidence of altered levels of acetylated histone H3 (show HIST3H3 Antibodies) at the affected allele compared to the common allele

  9. dysregulation in GRK3 expression alters signaling desensitization, and thereby predisposes to the development of bipolar disorder

  10. the CRH (show CRH Antibodies)-R1alpha carboxyl tail is important for regulation of receptor activity by G protein-coupled receptor (show ADRA1A Antibodies) kinase

Zebrafish Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

  1. beta-arrestin 2 (show ARRB2 Antibodies) and GRK2 (show ADRBK1 Antibodies) colocalize with S1p2 (show S1PR2 Antibodies) in developing zebrafish embryos and depletion of GRK2 (show ADRBK1 Antibodies) in the S1p2 (show S1PR2 Antibodies) R150H miles apart zebrafish partially rescued cardia bifida.

  2. GRK2 (show ADRBK1 Antibodies) and GRK5 (show GRK5 Antibodies) control cardiac function as well as morphogenesis during development although with different morphological outcomes.

  3. Data suggest that a G protein-coupled receptor (show GPBAR1 Antibodies) kinase, perhaps GRK2 (show ADRBK1 Antibodies) or 3, functions as a vertebrate kinase for Smoothened (show SMO Antibodies), promoting Hedgehog (show SHH Antibodies) signal transduction during early development.

  4. These data thus reveal a novel kinase activity-independent function for GRK (show GRK4 Antibodies) and establish a role for GRK2 (show ADRBK1 Antibodies) as a cell-cycle regulator (show CDKN2A Antibodies) during early embryonic development.

Cow (Bovine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

  1. Fusion proteins containing the c-terminus of GPCR kinase 3 (GRK3ct) and either the fluorescent protein cerulean or Renilla luciferase bind to venus-labeled Gbetagamma dimers, resulting in Forster or bioluminescence resonance energy transfer.

ADRBK2 Antigen Profile

Protein Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Gene names and symbols associated with ADRBK2

  • adrenergic, beta, receptor kinase 2 (ADRBK2) antibody
  • adrenergic, beta, receptor kinase 2 (adrbk2) antibody
  • adrenergic receptor kinase, beta 2 (Adrbk2) antibody
  • adrenergic, beta, receptor kinase 2 (Adrbk2) antibody
  • 4833444A01Rik antibody
  • Adrbk-2 antibody
  • AI851927 antibody
  • AW551196 antibody
  • Bark-2 antibody
  • BARK2 antibody
  • Grk3 antibody
  • si:dz221d18.1 antibody

Protein level used designations for ADRBK2

adrenergic, beta, receptor kinase 2 , beta-adrenergic receptor kinase 2-like , beta ARK2 , beta-ARK-2 , beta-adrenergic receptor kinase 2 , G-protein-coupled receptor kinase 3 , adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase) , G-protein coupled receptor kinase 2/3 , GRK2/3

GENE ID SPECIES
486327 Canis lupus familiaris
100065495 Equus caballus
100379889 Xenopus (Silurana) tropicalis
100396838 Callithrix jacchus
714510 Macaca mulatta
100156449 Sus scrofa
100614029 Pan troglodytes
320129 Mus musculus
157 Homo sapiens
25372 Rattus norvegicus
569403 Danio rerio
416904 Gallus gallus
282136 Bos taurus
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