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Aflatoxin Beta1 Aldehyde Reductase Proteins (AKR7A2)

The protein encoded by AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. Additionally we are shipping AKR7A2 Antibodies (60) and AKR7A2 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AKR7A2 8574 O43488
AKR7A2 171445 Q8CG45
AKR7A2 110198 Q8CG76
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Top AKR7A2 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$414.75
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,004.83
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details

AKR7A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced AKR7A2 Proteins

  1. Human AKR7A2 Protein expressed in Escherichia coli (E. coli) - ABIN667763 : Bodreddigari, Jones, Egner, Groopman, Sutter, Roebuck, Guengerich, Kensler, Sutter: Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3. in Chemical research in toxicology 2008 (PubMed)
    Show all 2 references for ABIN667763

  2. Human AKR7A2 Protein expressed in Wheat germ - ABIN1344772 : Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015 (PubMed)

More Proteins for Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) Interaction Partners

Human Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) interaction partners

  1. AKR7A2 contributes to protection against MG-induced toxicity.

  2. structure and tissue-related expression of AFAR genes on chromosome 1

  3. The human aldo-keto reductase AKR7A2 has been proposed previously to catalyze the NADPH (show NQO1 Proteins)-dependent reduction of succinic semialdehyde (SSA (show TRIM21 Proteins)) to gamma-Hydroxybutyrate in human brain

  4. The human AFAR gene family maps to a genomic region in 1p36 of frequent hemizygous deletions in various human cancers.

  5. Aflatoxin B(1) aldehyde reductase (show ADH1B Proteins) (AKR7A2) was confirmed to be only highly expressed in pancreatic cancer, not in normal adjacent pancreas and benign tumors.

Mouse (Murine) Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) interaction partners

  1. These findings indicate the importance of AKR7A5 in protecting cells from the damaging effects of oxidative stress, and that this cytoprotective function is carried out through multiple pathways.

  2. AKR7A5 has selective substrate specificity towards naphthoquinone derivatives, suggesting that the aldo-keto reductase could play an important role in metabolism of certain naphthoquinone derivatives.

  3. structure and tissue-related expression of AFAR genes

AKR7A2 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.

Gene names and symbols associated with AKR7A2

  • aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2)
  • aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (Akr7a2)
  • aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) (Akr7a5)
  • 0610025K21Rik protein
  • Afar protein
  • Afar1 protein
  • AFB1-AR1 protein
  • Aiar protein
  • AKR7 protein
  • Akr7a2 protein

Protein level used designations for AKR7A2

AFB1 aldehyde reductase 1 , AFB1-AR 1 , SSA reductase , aflatoxin B1 aldehyde reductase member 2 , aflatoxin beta1 aldehyde reductase , aldoketoreductase 7 , succinic semialdehyde reductase , rAFAR2

GENE ID SPECIES
8574 Homo sapiens
171445 Rattus norvegicus
110198 Mus musculus
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