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AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. Additionally we are shipping Angiotensin II Receptor-Associated Protein Proteins (4) and Angiotensin II Receptor-Associated Protein Kits (3) and many more products for this protein.
Showing 10 out of 47 products:
Human Monoclonal AGTRAP Primary Antibody for WB - ABIN395167
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN395167
A role for AT1 receptor-associated proteins in blood pressure regulation
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R (show AGTR1 Antibodies), plays a protective role against the development of systemic insulin (show INS Antibodies) resistance via regulatory effects on adipose tissue function.
The phosphatidylinositol transfer protein (show PITPNA Antibodies) RdgBbeta (show PITPNC1 Antibodies) binds 14-3-3 (show YWHAQ Antibodies) via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).
the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.
CSF (show CSF2 Antibodies) angiotensin II, ACE (show ACE Antibodies), and ACE2 (show ACE2 Antibodies) levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 (show AQP4 Antibodies) antibody, reflecting severe destruction of perivascular astrocytes
Small interfering RNA significantly attenuates angiotensin II type 1 receptor (show AGTR1 Antibodies)-stimulated inositol phosphate formation.
cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein
isolation of a novel protein, ARAP1 (show ARAP1 Antibodies), which promotes recycling of angiotensin(1A) to the plasma membrane in HEK (show EPHA3 Antibodies)-293 cells
CAML (show CAMLG Antibodies) is an important signal transducer for the actions of Ang II (show AGT Antibodies) in regulating the calcineurin (show PPP3CA Antibodies)-NFAT (show NFATC1 Antibodies) pathway and the interaction of CAML (show CAMLG Antibodies) with ATRAP may mediate the Ang II (show AGT Antibodies) actions in vascular physiology
These results suggest that increased formation of AT1R-P2Y6R (show P2RY6 Antibodies) heterodimers with age may increase the likelihood of hypertension induced by Ang II (show AGT Antibodies).
although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct
Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.
AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.
The inhibition of degradation of angiotensin II type 1 receptor (show AGTR1 Antibodies)-associated protein (show BCAP31 Antibodies) (ATRAP) and inactivation of AT1R-mediated p38 MAPK (show MAPK14 Antibodies) and STAT3 (show STAT3 Antibodies) signaling pathways, are involved cardiac hypertrophy.
Activation of aortic vascular ATRAP partially inhibits the Nox4 (show NOX4 Antibodies)/p22(phox (show CYBA Antibodies))-ROS (show ROS1 Antibodies)-p38MAPK (show MAPK14 Antibodies)/JNK (show MAPK8 Antibodies) pathway and pathological aortic hypertrophy provoked by Ang II (show AGT Antibodies)-mediated hypertension.
ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin (show INS Antibodies) resistance via regulatory effects on adipose tissue function.
AGTRAP expression is regulated by USF1 (show USF1 Antibodies) and USF2 (show USF2 Antibodies)
renal tubule-dominant ATRAP activation provokes no evident effects on blood pressure at baseline but exerts an inhibitory effect on the pathological elevation of blood pressure in response to angiotensin II stimulation
These data imply an involvement of AT1R in fetal development and of AT2R (show AGTR2 Antibodies) in adult function.
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
angiotensin II receptor-associated protein
, type-1 angiotensin II receptor-associated protein
, Type-1 angiotensin II receptor-associated protein
, AT1 receptor-associated protein
, ATI receptor-associated protein
, angiotensin II, type I receptor-associated protein
, AT1 receptor
, angiotensin II receptor, type I