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May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery (By similarity). Additionally we are shipping ANKRA2 Kits (9) and ANKRA2 Proteins (7) and many more products for this protein.
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Chicken Polyclonal ANKRA2 Primary Antibody for WB - ABIN2784282
Wang, Grégoire, Zika, Xiao, Li, Li, Wright, Ting, Yang: Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases. in The Journal of biological chemistry 2005
ANKRA, RFXANK, and CIITA are novel targets of class IIa HDACs which may deacetylases play a role in regulating MHCII expression
The findings of association in different populations with different SNPs support a conclusion that variation close to the ANKRA2/CD180 (show CD180 Antibodies) locus analysed in this study contributes to differential response to pathogen exposure.
Class II histone deacetylases (HDACs)4 and HDAC5 interact with the ankyrin repeats of ANKRA2 and regulatory factor X-associated ankyrin-containing protein and, through association with RFXANK, repress MHC II promoter activation
May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery (By similarity).
ankyrin repeat, family A (RFXANK-like), 2
, ankyrin repeat family A protein 2
, RFXANK-like protein 2
, SLO-interacting ankyrin-containing protein
, ankyrin-repeat family A protein