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Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 1 Proteins (APOBEC1)

APOBEC1 encodes a member of the cytidine deaminase enzyme family. Additionally we are shipping APOBEC1 Antibodies (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOBEC1 11810 P51908
APOBEC1 339 P41238
APOBEC1 25383 P38483
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Top APOBEC1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,575.83
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,575.83
Details
Yeast REACT_Opossum His tag   1 mg Log in to see 56 to 66 Days
$2,594.17
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,597.83
Details

APOBEC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1) Interaction Partners

Mouse (Murine) Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1) interaction partners

  1. Apobec-1-dependent C-to-U RNA editing exerts broad functional effects in a tissue-specific manner.

  2. RBM47 and APOBEC1 constitute the basic machinery for C to U RNA editing.

  3. In contrast to in vitro results, APOBEC1 neither inhibited nor significantly drove the molecular evolution of Friend retrovirus in wild type or APOBEC1 knockout mice.

  4. Individual genetic variability at the Apobec1 locus results in differential rates of C-to-U(T) editing in murine macrophages; with mouse strains expressing mostly a truncated alternative transcript isoform of Apobec1 exhibiting lower rates of editing.

  5. The transgenic rescue of intestinal apobec-1 expression restores C-to-U RNA editing of apoB (show APOB Proteins) mRNA in vivo, including the canonical site at position 6666 and also at approximately 20 other newly identified downstream sites present in WT mice.

  6. Results suggest that apo (show C9orf3 Proteins) B mRNA editing protein (Apobec1 cytidine deaminase (show CDA Proteins)) plays a central role in controlling testicular germ cell tumors susceptibility in both a conventional and a transgenerational manner.

  7. The transcriptomics approach to RNA editing presented in this study dramatically expands the list of APOBEC1 mRNA editing targets and reveals a novel cellular mechanism for the modification of transcript 3' UTRs.

  8. LDL receptor (show LDLR Proteins) and the apolipoprotein B (show APOB Proteins) mRNA editing enzyme Apobec1 are regulated via calcium signaling in mechanistic response to genetic, mechanical, and environmental insults that trigger an imbalance of intracellular calcium homeostasis

  9. studies establish the existence of preferential degradation of intestinal apolipoprotein B-100 (show APOB Proteins) and subtle defects in triglyceride secretion in apolipoprotein B editing complex 1-/- mice

  10. apobec-1 complementation factor (show A1CF Proteins) has a role in regulating nucleocytoplasmic import and shuttling

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1) interaction partners

  1. AICDA (show AICDA Proteins)/APOBEC family of cytidine deaminases is significant in innate immunity, as it restricts numerous viruses, including HBV, through hypermutationdependent and independent mechanisms. (Review)

  2. Results show that expression of APOBEC1 induces a mutator phenotype in 2 different cellular models.

  3. hnRNPQ6 is required for APOBEC1-enhanced IL8 (show IL8 Proteins) production.

  4. Studies indicate the APOBEC family consists of 11 members: APOBEC-1 (Apo1), APOBEC-2 (Apo2), activation induced cytidine deaminase (AID), APOBEC- 3A, -3B, -3C, -3DE, -3F, -3H (Apo3A-H) and APOBEC- 4 (Apo4).

  5. The hypermutation activity of APOBEC-1 was decreased to background levels by a single point APOBEC-1 mutation of P29F or E181Q, while 50% of wild-type control editing at the normal site was retained.

  6. The data presented in this report suggested that similar regulatory mechanisms controlling the functional interaction of APOBEC-1 with ACF (show A1CF Proteins) might be operational during enterocyte differentiation.

  7. Identified two novel variants, rs1349411 (APOBEC1) and rs1424032, for serum apoB (show APOB Proteins) levels in Mexicans.

  8. C-->U editing of neurofibromatosis 1 (show NF1 Proteins) mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B (show APOB Proteins) mRNA-editing enzyme

  9. expression of two proteins essential for apolipoprotein B (show APOB Proteins) mRNA editing from a single gene through alternative splicing

  10. apobec-1 complementation factor (show A1CF Proteins) has a role in regulating nucleocytoplasmic import and shuttling

Rabbit Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1) interaction partners

  1. A moderate reduction of the APOBEC1 dependent editing induces a lean phenotype at least in the rabbit species.

APOBEC1 Protein Profile

Protein Summary

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.

Gene names and symbols associated with APOBEC1

  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (APOBEC1)
  • APOBEC1 complementation factor (A1CF)
  • apobec1 complementation factor (a1cf)
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1)
  • A1CF protein
  • ACF protein
  • APOBEC-1 protein
  • APOBEC1 protein
  • BEDP protein
  • CDAR1 protein
  • HEPR protein
  • REPR protein

Protein level used designations for APOBEC1

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 , C->U-editing enzyme APOBEC-1 , apolipoprotein B mRNA editing enzyme complex 1 , apolipoprotein B mRNA-editing enzyme 1 , APOBEC1 complementation factor , apobec-1 complementation factor , acf , APOBEC1-stimulating protein , apobec-1 complementation factor-like , APOBEC1 complementation factor-like , apolipoprotein B editing complex 1 , apolipoprotein B mRNA editing enzyme complex-1 , apolipoprotein B mRNA editing protein , Apolipoprotein B editing protein , Apolipoprotein B mRNA-editing enzyme 1 , apolipoprotein B mRNA editing catalytic subunit-1

GENE ID SPECIES
486699 Canis lupus familiaris
516043 Bos taurus
554187 Monodelphis domestica
715554 Macaca mulatta
748253 Pan troglodytes
466076 Pan troglodytes
562916 Danio rerio
613704 Bos taurus
100071844 Equus caballus
100174508 Pongo abelii
100370615 Saccoglossus kowalevskii
100389343 Callithrix jacchus
100468305 Ailuropoda melanoleuca
11810 Mus musculus
339 Homo sapiens
100009191 Oryctolagus cuniculus
25383 Rattus norvegicus
101825976 Mesocricetus auratus
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