Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B Proteins (APOBEC3B)

APOBEC3B is a member of the cytidine deaminase gene family. Additionally we are shipping APOBEC3B Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOBEC3B 9582 Q9UH17
APOBEC3B 315137  
APOBEC3B    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top APOBEC3B Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cricetulus longicaudatus His tag   1 mg Log in to see 60 to 71 Days
$3,094.67
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,197.33
Details

APOBEC3B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Cricetulus longicaudatus

More Proteins for Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) Interaction Partners

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) interaction partners

  1. SNPs in APOBEC3 (show APOBEC3F Proteins) alter expression of APOBEC3A (show APOBEC3A Proteins)/APOBEC3B to affect somatic APOBEC-signature mutations.

  2. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation have been reported.

  3. A lysine-free derivative of human APOBEC3B was constructed and shown to be indistinguishable from the wild-type enzyme in DNA cytosine deamination, HIV-1 restriction, and nuclear localization activities.

  4. exposures to relevant environmental factors might induce APOBEC3A (show APOBEC3A Proteins) or APOBEC3B expression above genotoxic levels and initiate tumorigenesis in a tissue-specific manner in the right cellular environment where ssDNA is available

  5. APOBEC3B expression increased the incorporation of genomic uracil, invoked DNA damage response (DDR (show DDR1 Proteins)) biomarkers and caused cell cycle arrest.

  6. The findings demonstrate that covalently-closed circular DNA levels are significantly lower in hepatocellular carcinoma tissues, and that the lower levels are likely to stem in part from up-regulation of APOBEC3B.

  7. Data suggest that heat shock proteins, in particular Hsp90 (show HSP90 Proteins), stimulate APOBEC3 (show APOBEC3F Proteins)-mediated DNA deamination activity toward hepatitis B viral DNA, suggesting a potential physiological role in mutagenesis/carcinogenesis and viral innate immunity; Hsp90 (show HSP90 Proteins) stimulates deamination activity of APOBEC3G (show APOBEC3G Proteins), APOBEC3B, and APOBEC3C (show APOBEC3C Proteins) during co-expression in human liver HepG2 cells.

  8. APOBEC3B mRNA levels are significantly higher in breast cancer metastases as compared to the corresponding estrogen receptor (show ESR1 Proteins)-positive primary tumors.

  9. tumour-infiltrating immune cells may be an important feature of breast cancers arising in women with APOBEC3B germline deletion, and that this may be of particular interest in Asian women where the germline deletion is more common.

  10. the APOBEC3B deletion polymorphism has neither a prognostic nor a predictive value for breast cancer patients.

APOBEC3B Protein Profile

Protein Summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with APOBEC3B

  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (APOBEC3B)
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (Apobec3b)
  • A3B protein
  • APOBEC1L protein
  • Apobec3 protein
  • APOBEC3B protein
  • Apobec3f protein
  • APOBEC3H protein
  • APOBEC3Z2 protein
  • APOBEC3Z3 protein
  • ARCD3 protein
  • ARP4 protein
  • bK150C2.2 protein
  • DJ742C19.2 protein
  • PHRBNL protein

Protein level used designations for APOBEC3B

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D , probable DNA dC->dU-editing enzyme APOBEC-3B , apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B , DNA dC->dU-editing enzyme APOBEC-3B , cytidine deaminase , phorbolin 2 , phorbolin 3 , phorbolin-1-related protein , phorbolin-2/3 , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F , DNA dC->dU-editing enzyme APOBEC3 , apolipoprotein B editing complex 3 , probable DNA dC->dU-editing enzyme APOBEC3

GENE ID SPECIES
481248 Canis lupus familiaris
743891 Pan troglodytes
100628312 Macaca mulatta
9582 Homo sapiens
504505 Bos taurus
315137 Rattus norvegicus
Selected quality suppliers for APOBEC3B Proteins (APOBEC3B)
Did you look for something else?