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anti-Apolipoprotein E (APOE) Antibodies

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Additionally we are shipping APOE Kits (104) and APOE Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOE 11816 P08226
APOE 348 P02649
APOE 25728 P02650
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Top anti-APOE Antibodies at antibodies-online.com

Showing 10 out of 321 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB AP14244PU-N Apolipoprotein E antibody staining of Formalin-Fixed, Para... Western blot: Apolipoprotein E antibody staining of 293 cell lysates (... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of APOE(arrow) using rabbit polyclonal APOE Anti... Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reac... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185375 (0.1µg/ml) staining of Human Brain lysate (35µg protein in ... ABIN185375 (2.5µg/ml) staining of paraffin embedded Human Liver. Steam... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human APOE in human liver with rabbit polyc... 100 μg Log in to see 16 Days
$308.00
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of HepG2 cells using ApoE mouse mAb... 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
$456.50
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung carcinoma labeled with A... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details

APOE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
,
Human , , , ,
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Rat (Rattus) , , , ,

Top referenced anti-APOE Antibodies

  1. Human Polyclonal APOE Primary Antibody for IHC (p), ELISA - ABIN1997537 : Li, Jiang, Qu, Yao, Cai, Chen, Peng: Hepatocyte nuclear factor 4? and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus. in Journal of virology 2013 (PubMed)
    Show all 2 references for ABIN1997537

  2. Human Monoclonal APOE Primary Antibody for FACS, IHC - ABIN968962 : Karpouzis, Caridha, Tripsianis, Michailidis, Martinis, Veletza: Apolipoprotein E gene polymorphism in psoriasis. in Archives of dermatological research 2009 (PubMed)
    Show all 2 references for ABIN968962

  3. Human Monoclonal APOE Primary Antibody for EIA, IHC (fro) - ABIN1105420 : Dergunov, Shuvaev, Yanushevskaja: Quaternary structure of apolipoprotein E in solution: fluorimetric, chromatographic and immunochemical studies. in Biological chemistry Hoppe-Seyler 1992 (PubMed)
    Show all 2 references for ABIN1105420

  4. Human Polyclonal APOE Primary Antibody for IHC, WB - ABIN2774066 : Ho, Niti, Yap, Kua, Ng: Metabolic syndrome and cognitive decline in chinese older adults: results from the singapore longitudinal ageing studies. in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 (PubMed)
    Show all 2 references for ABIN2774066

  5. Human Polyclonal APOE Primary Antibody for IHC, ELISA - ABIN185375 : Dodart, Marr, Koistinaho, Gregersen, Malkani, Verma, Paul: Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN185375

  6. Human Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN1386767 : Liu, Gao, Hao, Lou, Zhang, Li, Wu, Xiao, Yang, Li, Qiu, Wang: Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis. in Molecular biology reports 2014 (PubMed)

  7. Mouse (Murine) Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN725750 : Chiu, Chan, Yang, Liu, Chiang: Supplementation of Chitosan Alleviates High-Fat Diet-Enhanced Lipogenesis in Rats via Adenosine Monophosphate (AMP)-Activated Protein Kinase Activation and Inhibition of Lipogenesis-Associated Genes. in Journal of agricultural and food chemistry 2015 (PubMed)

  8. Human Polyclonal APOE Primary Antibody for EIA, IHC (p) - ABIN359760 : Wood, Fullerton, El-Sohemy, Bakovic: Interactions between hepatic lipase and apolipoprotein E gene polymorphisms affect serum lipid profiles of healthy Canadian adults. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2008 (PubMed)

  9. Human Polyclonal APOE Primary Antibody for IHC (p), WB - ABIN391849 : Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. in Hepatology (Baltimore, Md.) 2009 (PubMed)

More Antibodies against APOE Interaction Partners

Mouse (Murine) Apolipoprotein E (APOE) interaction partners

  1. ApoE(-/-) mice receiving WD showed abnormal glucose tolerance, hepatomegaly, weight gain and full spectrum of NASH (show SAMSN1 Antibodies) including hepatic steatosis, fibrosis and inflammation, with no sign of renal damage

  2. Long-lasting exposure to ox-LDL decreases the expression of Sirt1 (show SIRT1 Antibodies) and Runx2 (show RUNX2 Antibodies) in bone mesenchymal stem cells which may explain the decreased bone formation in aged apoE(-/-) mice.

  3. Report acceleration of atherogenesis in ApoE-/- mice exposed to acute or low-dose-rate ionizing radiation.

  4. Fondaparinux, the selective FXa (show F10 Antibodies) inhibitor, can promote the stability of atherosclerotic lesions in apolipoprotein E-deficient mice.

  5. The literatures were searched extensively and this review was performed to review the signaling pathway factors expression in renal tissue of apoE-knockout mice. [review]

  6. Murine norovirus 4 has the potential to exert a variable and unpredictable effect on atherosclerosis in ApoE(-/-) mice.

  7. apoE exerts moderate sex-specific effects on experimental autoimmune encephalomyelitis severity

  8. the effect of T-bet deletion in apolipoproteinE (ApoE) knockout mice fed a high fat diet (HFD) or normal chow diet, was studied.

  9. The use of dietary interventions to slow the progression Alzheimer's disease should take ApoE genotype into consideration.

  10. FXI (show F11 Antibodies) deprivation was shown to slow down atherogenesis in Apoe knockout mice.

Human Apolipoprotein E (APOE) interaction partners

  1. elevated brain iron adversely impacts Alzheimer's Disease (AD) progression, brain iron elevation is a possible mechanism for APOE-epsilon4 being the major genetic risk factor for AD

  2. Apolipoprotein E allele e2 and genotype e2/e3 were risk factors for type 2 diabetic nephropathy (T2DN) and allele e3 and genotype e3/e3 played a protective role in T2DN

  3. The apolipoprotein E genotype is a powerful risk factor for late-onset Alzheimer's disease.

  4. APOE epsilon4, but not epsilon2, is associated with capillary amyloid angiopathy.

  5. ApoE is located in the nucleus and on the ApoD (show APOD Antibodies) promoter in human hepatic and glioblastoma cells lines.

  6. Serum apoE is associated with long-term risk of Alzheimer's disease in the general population, independent of APOE genotype.

  7. elderly community dwelling residents of Han ethnicity carrying the APOE epsilon3/epsilon3 genotype might have higher plasma glucose levels and a higher occurrence of diabetes.

  8. Neither total ApoE and ApoE4 levels nor the ApoE/ApoE4 ratio correlated with the diagnosis of Alzheimer's disease.

  9. Results showed that women who possessed any APOE epsilon4 allele experienced a steeper decline in BMI in late life, after age 70 years, irrespective of dementia status

  10. This study demonstrated that APOE and BDNF (show BDNF Antibodies) polymorphisms moderate amyloid beta-related cognitive decline in preclinical Alzheimer's disease.

Rabbit Apolipoprotein E (APOE) interaction partners

  1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease.

  2. The molar ratio ApoE/ApoA-I (show APOA1 Antibodies) is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.

  3. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 Antibodies) paraoxonase activity

  4. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences.

Pig (Porcine) Apolipoprotein E (APOE) interaction partners

  1. These data suggest that the -155T>A mutation in the promoter region of the porcine APOE gene is an important functional variant

Cow (Bovine) Apolipoprotein E (APOE) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE, MTP (show MTTP Antibodies), and LDLR (show LDLR Antibodies), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. Bovine apoE contents in triglyceride-rich lipoproteins are modulated by nutritional treatment and closely associated with triglyceride-rich lipoprotein metabolism

  3. apoE-containing particles, which increased during the lactating stage, were not associated with HDL (show HSD11B1 Antibodies) particles, and lipid-free forms were included in cow plasma

  4. after calving the apolipoprotein B(100 (show APOB Antibodies)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (show MTTP Antibodies)) and apolipoprotein E messenger RNA abundance were higher in the liver

Chimpanzee Apolipoprotein E (APOE) interaction partners

  1. The study found no coding variation within and between chimpanzee populations, suggesting that the maintenance of functionally diverse APOE polymorphisms is a unique feature of human evolution.

  2. ApoE evolution and very likely the evolution of other apolipoproteins are influenced by feeding environment and diet of humans, chimpanzees and various other species.

Rhesus Monkey Apolipoprotein E (APOE) interaction partners

  1. In the hippocampus APOE protein levels were higher in good spatial performers than poor spatial performers animals

  2. Allele frequencies of the ApoE gene found show that allele epsilon3 has one of the highest frequencies and epsilon4 allele one of the lowest compared to other population groups in the world

  3. There was significantly more apoE immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

APOE Antigen Profile

Protein Summary

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Gene names and symbols associated with anti-Apolipoprotein E (APOE) Antibodies

  • apolipoprotein E (apoe) antibody
  • apolipoprotein Ea (apoea) antibody
  • apolipoprotein E (Apoe) antibody
  • apolipoprotein E (APOE) antibody
  • AD2 antibody
  • AI255918 antibody
  • Apo-E antibody
  • apoe antibody
  • APOEA antibody
  • apoprotein antibody
  • im:7036787 antibody
  • LDLCQ5 antibody
  • LPG antibody
  • wu:fb69a05 antibody
  • zgc:110064 antibody

Protein level used designations for anti-Apolipoprotein E (APOE) Antibodies

apolipoprotein E , ApoE-1 , apo-E , apolipoprotein E3

GENE ID SPECIES
394678 Xenopus (Silurana) tropicalis
553587 Danio rerio
100136023 Oncorhynchus mykiss
100380959 Xenopus laevis
11816 Mus musculus
348 Homo sapiens
100009337 Oryctolagus cuniculus
25728 Rattus norvegicus
397576 Sus scrofa
100731633 Cavia porcellus
281004 Bos taurus
476438 Canis lupus familiaris
449586 Pan troglodytes
714623 Macaca mulatta
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