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anti-Apolipoprotein E (APOE) Antibodies

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Additionally we are shipping APOE Kits (104) and APOE Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOE 11816 P08226
APOE 348 P02649
APOE 25728 P02650
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Top anti-APOE Antibodies at antibodies-online.com

Showing 10 out of 336 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB AP14244PU-N Apolipoprotein E antibody staining of Formalin-Fixed, Paraffin-Embedded Human Hepatocarcinoma tissue which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot: Apolipoprotein E antibody staining of 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the APOE gene (Lane 2). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of APOE(arrow) using rabbit polyclonal APOE Antibody (C-term) (ABIN391849). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the APOE gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOE antibody (C-term) (ABIN391849), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185375 (0.1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185375 (2.5µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of HepG2 cells using ApoE mouse mAb (green) and negative control (purple) . 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
$456.50
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung carcinoma labeled with Anti-APOE/Apo E2 Polyclonal Antibody, Unconjugated (ABIN725750) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human APOE in human liver with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
$308.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details

APOE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-APOE Antibodies

  1. Human Monoclonal APOE Primary Antibody for FACS, IHC - ABIN968962 : Karpouzis, Caridha, Tripsianis, Michailidis, Martinis, Veletza: Apolipoprotein E gene polymorphism in psoriasis. in Archives of dermatological research 2009 (PubMed)
    Show all 2 references for ABIN968962

  2. Human Monoclonal APOE Primary Antibody for EIA, IHC (fro) - ABIN1105420 : Dergunov, Shuvaev, Yanushevskaja: Quaternary structure of apolipoprotein E in solution: fluorimetric, chromatographic and immunochemical studies. in Biological chemistry Hoppe-Seyler 1992 (PubMed)
    Show all 2 references for ABIN1105420

  3. Human Polyclonal APOE Primary Antibody for IHC (p), ELISA - ABIN1997537 : Li, Jiang, Qu, Yao, Cai, Chen, Peng: Hepatocyte nuclear factor 4? and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus. in Journal of virology 2013 (PubMed)
    Show all 2 references for ABIN1997537

  4. Human Polyclonal APOE Primary Antibody for IHC, WB - ABIN2774066 : Ho, Niti, Yap, Kua, Ng: Metabolic syndrome and cognitive decline in chinese older adults: results from the singapore longitudinal ageing studies. in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 (PubMed)
    Show all 2 references for ABIN2774066

  5. Human Polyclonal APOE Primary Antibody for IHC, ELISA - ABIN185375 : Dodart, Marr, Koistinaho, Gregersen, Malkani, Verma, Paul: Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN185375

  6. Human Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN1386767 : Liu, Gao, Hao, Lou, Zhang, Li, Wu, Xiao, Yang, Li, Qiu, Wang: Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis. in Molecular biology reports 2014 (PubMed)

  7. Human Polyclonal APOE Primary Antibody for EIA, IHC (p) - ABIN359760 : Wood, Fullerton, El-Sohemy, Bakovic: Interactions between hepatic lipase and apolipoprotein E gene polymorphisms affect serum lipid profiles of healthy Canadian adults. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2008 (PubMed)

  8. Mouse (Murine) Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN725750 : Chiu, Chan, Yang, Liu, Chiang: Supplementation of Chitosan Alleviates High-Fat Diet-Enhanced Lipogenesis in Rats via Adenosine Monophosphate (AMP)-Activated Protein Kinase Activation and Inhibition of Lipogenesis-Associated Genes. in Journal of agricultural and food chemistry 2015 (PubMed)

  9. Human Polyclonal APOE Primary Antibody for IHC (p), WB - ABIN391849 : Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. in Hepatology (Baltimore, Md.) 2009 (PubMed)

More Antibodies against APOE Interaction Partners

Mouse (Murine) Apolipoprotein E (APOE) interaction partners

  1. Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.

  2. These findings may be clinically relevant because HDL's APOE content associates with CVD risk and ABCA1 (show ABCA1 Antibodies) deficiency promotes unregulated cholesterol accumulation in human macrophages.

  3. study demonstrated ApoE4-containing astrocyte-conditioned media increases mitochondria-associated endoplasmic reticulum membranes (MAM (show ATF7IP Antibodies)) function relative to ApoE3; data are consistent with a role of upregulated MAM (show ATF7IP Antibodies) function in the pathogenesis of Alzheimer disease and may help explain the contribution of ApoE4 as a risk factor in the disease

  4. Neurometabolic roles of ApoE and Ldl-R in mouse brain.

  5. Suggest Idol (show MYLIP Antibodies) as a gatekeeper of LDLR (show LDLR Antibodies)-dependent ApoE and Abeta (show APP Antibodies) clearance in the brain and a potential enzyme target for therapeutic intervention in Alzheimer disease.

  6. Systemic administration of irisin (show FNDC5 Antibodies) may be protected against endothelial injury and ameliorated atherosclerosis in apoE(-/-) diabetic mice.

  7. NPY (show NPY Antibodies) might be involved in the pathogenesis of METH (show MTRR Antibodies)-induced atherogenic effects through NPY (show NPY Antibodies) Y1 receptor pathway in ApoE knockout mice

  8. Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE- and ApoE/GPx1 (show GPX1 Antibodies)-deficient mice.

  9. Cx37 (show GJA4 Antibodies) deletion increased the size of atherosclerotic lesions in oscillatory shear stress regions and abrogated the development of a stable plaque phenotype under OSS in ApoE(-/-) mice

  10. When chronic allergic lung inflammation (ALI)and atherosclerosis were produced simultaneously, ALI increased atherosclerotic lesion size, inflammatory cell content, elastin (show ELN Antibodies) fragmentation, smooth muscle cell loss, lesion cell proliferation, and apoptosis.

Human Apolipoprotein E (APOE) interaction partners

  1. Subjective memory complaints was associated with high Abeta (show APP Antibodies) burden, especially in APOEepsilon4 carriers and younger subjects

  2. Carrying APOE*4 alleles increases MetS (show ETV3 Antibodies) in a dose-dependent manner, characterizing individual's APOE genotype might help identify at-risk subjects for preventive intervention.

  3. suggested that ApoE may have a role in the pathogenesis and progression of HBV-related liver disease and indicated the possible underlying mechanisms

  4. ApoE mutations may have a role in increasing the development of diabetic nephropathy among the Egyptian individuals.

  5. The data suggest that the APOE-epsilon4 allele is protective against attention deficit and especially against poor working memory in Hepatitis C virus-infected subjects with mild liver disease.

  6. We demonstrated the benefits of a questionnaire-based approach for assessment of lifestyle risk factors to facilitate clinical interpretation of APOE genotyping genetic subgroup of dyslipidemic patients

  7. The possession of the APOE epsilon4 allele has a small, nonsignificant effect on the presence of delirium. It seems that there is no association between APOE and the occurrence of delirium.[review; meta-analysis]

  8. The results of this study shows that the frequency of epsilon4 allele of ApoE is significantly lower among hypertensive patients on hemodialysis with the highest levels of Asymmetric dimethylarginine .

  9. study demonstrated ApoE4-containing astrocyte-conditioned media increases mitochondria-associated endoplasmic reticulum membranes (MAM (show ATF7IP Antibodies)) function relative to ApoE3; data are consistent with a role of upregulated MAM (show ATF7IP Antibodies) function in the pathogenesis of Alzheimer disease and may help explain the contribution of ApoE4 as a risk factor in the disease

  10. In older surgery patients free of dementia, the findings do not support the hypothesis that the ApoE genotype does not confer either risk or protection in postoperative delirium incidence, severity, or duration.

Rabbit Apolipoprotein E (APOE) interaction partners

  1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease.

  2. The molar ratio ApoE/ApoA-I (show APOA1 Antibodies) is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.

  3. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 Antibodies) paraoxonase activity

  4. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences.

Pig (Porcine) Apolipoprotein E (APOE) interaction partners

  1. These data suggest that the -155T>A mutation in the promoter region of the porcine APOE gene is an important functional variant

Cow (Bovine) Apolipoprotein E (APOE) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE, MTP (show MTTP Antibodies), and LDLR (show LDLR Antibodies), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. Bovine apoE contents in triglyceride-rich lipoproteins are modulated by nutritional treatment and closely associated with triglyceride-rich lipoprotein metabolism

  3. apoE-containing particles, which increased during the lactating stage, were not associated with HDL (show HSD11B1 Antibodies) particles, and lipid-free forms were included in cow plasma

  4. after calving the apolipoprotein B(100 (show APOB Antibodies)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (show MTTP Antibodies)) and apolipoprotein E messenger RNA abundance were higher in the liver

Chimpanzee Apolipoprotein E (APOE) interaction partners

  1. The study found no coding variation within and between chimpanzee populations, suggesting that the maintenance of functionally diverse APOE polymorphisms is a unique feature of human evolution.

  2. ApoE evolution and very likely the evolution of other apolipoproteins are influenced by feeding environment and diet of humans, chimpanzees and various other species.

Rhesus Monkey Apolipoprotein E (APOE) interaction partners

  1. In the hippocampus APOE protein levels were higher in good spatial performers than poor spatial performers animals

  2. Allele frequencies of the ApoE gene found show that allele epsilon3 has one of the highest frequencies and epsilon4 allele one of the lowest compared to other population groups in the world

  3. There was significantly more apoE immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

APOE Antigen Profile

Protein Summary

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Gene names and symbols associated with anti-Apolipoprotein E (APOE) Antibodies

  • apolipoprotein E (apoe) antibody
  • apolipoprotein Ea (apoea) antibody
  • apolipoprotein E (Apoe) antibody
  • apolipoprotein E (APOE) antibody
  • AD2 antibody
  • AI255918 antibody
  • Apo-E antibody
  • apoe antibody
  • APOEA antibody
  • apoprotein antibody
  • im:7036787 antibody
  • LDLCQ5 antibody
  • LPG antibody
  • wu:fb69a05 antibody
  • zgc:110064 antibody

Protein level used designations for anti-Apolipoprotein E (APOE) Antibodies

apolipoprotein E , ApoE-1 , apo-E , apolipoprotein E3

GENE ID SPECIES
394678 Xenopus (Silurana) tropicalis
553587 Danio rerio
100136023 Oncorhynchus mykiss
100380959 Xenopus laevis
11816 Mus musculus
348 Homo sapiens
100009337 Oryctolagus cuniculus
25728 Rattus norvegicus
397576 Sus scrofa
100731633 Cavia porcellus
281004 Bos taurus
476438 Canis lupus familiaris
449586 Pan troglodytes
714623 Macaca mulatta
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