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anti-Apolipoprotein E (APOE) Antibodies

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Additionally we are shipping APOE Kits (104) and APOE Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOE 11816 P08226
APOE 348 P02649
APOE 25728 P02650
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Top anti-APOE Antibodies at

Showing 10 out of 321 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB AP14244PU-N Apolipoprotein E antibody staining of Formalin-Fixed, Para... Western blot: Apolipoprotein E antibody staining of 293 cell lysates (... 0.4 mL Log in to see 6 to 8 Days
Human Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of APOE(arrow) using rabbit polyclonal APOE Anti... Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reac... 400 μL Log in to see 10 to 11 Days
Human Goat Un-conjugated IHC, ELISA, WB ABIN185375 (0.1µg/ml) staining of Human Brain lysate (35µg protein in ... ABIN185375 (2.5µg/ml) staining of paraffin embedded Human Liver. Steam... 100 μg Log in to see 4 to 5 Days
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human APOE in human liver with rabbit polyc... 100 μg Log in to see 16 Days
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of HepG2 cells using ApoE mouse mAb... 100 μL Log in to see 3 to 4 Days
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung carcinoma labeled with A... 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days

APOE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,
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Top referenced anti-APOE Antibodies

  1. Human Polyclonal APOE Primary Antibody for IHC (p), ELISA - ABIN1997537 : Li, Jiang, Qu, Yao, Cai, Chen, Peng: Hepatocyte nuclear factor 4? and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus. in Journal of virology 2013 (PubMed)
    Show all 2 references for ABIN1997537

  2. Human Monoclonal APOE Primary Antibody for FACS, IHC - ABIN968962 : Karpouzis, Caridha, Tripsianis, Michailidis, Martinis, Veletza: Apolipoprotein E gene polymorphism in psoriasis. in Archives of dermatological research 2009 (PubMed)
    Show all 2 references for ABIN968962

  3. Human Monoclonal APOE Primary Antibody for EIA, IHC (fro) - ABIN1105420 : Dergunov, Shuvaev, Yanushevskaja: Quaternary structure of apolipoprotein E in solution: fluorimetric, chromatographic and immunochemical studies. in Biological chemistry Hoppe-Seyler 1992 (PubMed)
    Show all 2 references for ABIN1105420

  4. Human Polyclonal APOE Primary Antibody for IHC, WB - ABIN2774066 : Ho, Niti, Yap, Kua, Ng: Metabolic syndrome and cognitive decline in chinese older adults: results from the singapore longitudinal ageing studies. in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 (PubMed)
    Show all 2 references for ABIN2774066

  5. Human Polyclonal APOE Primary Antibody for IHC, ELISA - ABIN185375 : Dodart, Marr, Koistinaho, Gregersen, Malkani, Verma, Paul: Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN185375

  6. Human Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN1386767 : Liu, Gao, Hao, Lou, Zhang, Li, Wu, Xiao, Yang, Li, Qiu, Wang: Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis. in Molecular biology reports 2014 (PubMed)

  7. Mouse (Murine) Polyclonal APOE Primary Antibody for IF (p), IHC (p) - ABIN725750 : Chiu, Chan, Yang, Liu, Chiang: Supplementation of Chitosan Alleviates High-Fat Diet-Enhanced Lipogenesis in Rats via Adenosine Monophosphate (AMP)-Activated Protein Kinase Activation and Inhibition of Lipogenesis-Associated Genes. in Journal of agricultural and food chemistry 2015 (PubMed)

  8. Human Polyclonal APOE Primary Antibody for EIA, IHC (p) - ABIN359760 : Wood, Fullerton, El-Sohemy, Bakovic: Interactions between hepatic lipase and apolipoprotein E gene polymorphisms affect serum lipid profiles of healthy Canadian adults. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2008 (PubMed)

  9. Human Polyclonal APOE Primary Antibody for IHC (p), WB - ABIN391849 : Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles. in Hepatology (Baltimore, Md.) 2009 (PubMed)

More Antibodies against APOE Interaction Partners

Mouse (Murine) Apolipoprotein E (APOE) interaction partners

  1. Systemic administration of irisin (show FNDC5 Antibodies) may be protected against endothelial injury and ameliorated atherosclerosis in apoE(-/-) diabetic mice.

  2. NPY (show NPY Antibodies) might be involved in the pathogenesis of METH (show MTRR Antibodies)-induced atherogenic effects through NPY (show NPY Antibodies) Y1 receptor pathway in ApoE knockout mice

  3. Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE- and ApoE/GPx1 (show GPX1 Antibodies)-deficient mice.

  4. Cx37 (show GJA4 Antibodies) deletion increased the size of atherosclerotic lesions in oscillatory shear stress regions and abrogated the development of a stable plaque phenotype under OSS in ApoE(-/-) mice

  5. When chronic allergic lung inflammation (ALI)and atherosclerosis were produced simultaneously, ALI increased atherosclerotic lesion size, inflammatory cell content, elastin (show ELN Antibodies) fragmentation, smooth muscle cell loss, lesion cell proliferation, and apoptosis.

  6. ApoE(-/-) mice receiving WD showed abnormal glucose tolerance, hepatomegaly, weight gain and full spectrum of NASH (show SAMSN1 Antibodies) including hepatic steatosis, fibrosis and inflammation, with no sign of renal damage

  7. Long-lasting exposure to ox-LDL decreases the expression of Sirt1 (show SIRT1 Antibodies) and Runx2 (show RUNX2 Antibodies) in bone mesenchymal stem cells which may explain the decreased bone formation in aged apoE(-/-) mice.

  8. Report acceleration of atherogenesis in ApoE-/- mice exposed to acute or low-dose-rate ionizing radiation.

  9. Fondaparinux, the selective FXa (show F10 Antibodies) inhibitor, can promote the stability of atherosclerotic lesions in apolipoprotein E-deficient mice.

  10. The literatures were searched extensively and this review was performed to review the signaling pathway factors expression in renal tissue of apoE-knockout mice. [review]

Human Apolipoprotein E (APOE) interaction partners

  1. The results suggest that education and female gender, not APOE genotype, may be important as independent strong predictive factors for disease progression in patients with early-onset Alzheimer's disease.

  2. C2238/alphaANP downregulates ApoE in vascular smooth muscle cells through type C natriuretic peptide receptor-dependent activation of Egr-1 (show EGR1 Antibodies) and the consequent upregulation of miR199a.

  3. Sporadic Abeta (show APP Antibodies) accumulation may be partly associated with increased amyloidogenic APP (show APP Antibodies) production, especially in APOE varepsilon4-negative subjects.

  4. The APOE epsilon2 allele increases the risk of Frontotemporal Dementia in ALS patients.

  5. Single-nucleotide polymorphisms in APOE gene is associated with Alzheimer's disease.

  6. Strong association between ApoE e4 allele and AD.

  7. Higher peak velocity-reactivity in APOE epsilon4 carriers suggests vascular compensation for deleterious effects of this known risk allele for Alzheimer's disease and stroke

  8. APOE-epsilon4 carriers showed an inability to effectively modulate posteromedial cortex during scene, but not face and object, working memory and perception.

  9. These results demonstrate that the impact of cerebrovascular risk on cortical thickness integrity may vary by the presence or absence of the APOE-4 allele, a well-known risk factor for Alzheimer's disease.

  10. Our results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults.

Rabbit Apolipoprotein E (APOE) interaction partners

  1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease.

  2. The molar ratio ApoE/ApoA-I (show APOA1 Antibodies) is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.

  3. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 Antibodies) paraoxonase activity

  4. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences.

Pig (Porcine) Apolipoprotein E (APOE) interaction partners

  1. These data suggest that the -155T>A mutation in the promoter region of the porcine APOE gene is an important functional variant

Cow (Bovine) Apolipoprotein E (APOE) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE, MTP (show MTTP Antibodies), and LDLR (show LDLR Antibodies), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. Bovine apoE contents in triglyceride-rich lipoproteins are modulated by nutritional treatment and closely associated with triglyceride-rich lipoprotein metabolism

  3. apoE-containing particles, which increased during the lactating stage, were not associated with HDL (show HSD11B1 Antibodies) particles, and lipid-free forms were included in cow plasma

  4. after calving the apolipoprotein B(100 (show APOB Antibodies)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (show MTTP Antibodies)) and apolipoprotein E messenger RNA abundance were higher in the liver

Chimpanzee Apolipoprotein E (APOE) interaction partners

  1. The study found no coding variation within and between chimpanzee populations, suggesting that the maintenance of functionally diverse APOE polymorphisms is a unique feature of human evolution.

  2. ApoE evolution and very likely the evolution of other apolipoproteins are influenced by feeding environment and diet of humans, chimpanzees and various other species.

Rhesus Monkey Apolipoprotein E (APOE) interaction partners

  1. In the hippocampus APOE protein levels were higher in good spatial performers than poor spatial performers animals

  2. Allele frequencies of the ApoE gene found show that allele epsilon3 has one of the highest frequencies and epsilon4 allele one of the lowest compared to other population groups in the world

  3. There was significantly more apoE immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

APOE Antigen Profile

Protein Summary

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Gene names and symbols associated with anti-Apolipoprotein E (APOE) Antibodies

  • apolipoprotein E (apoe) antibody
  • apolipoprotein Ea (apoea) antibody
  • apolipoprotein E (Apoe) antibody
  • apolipoprotein E (APOE) antibody
  • AD2 antibody
  • AI255918 antibody
  • Apo-E antibody
  • apoe antibody
  • APOEA antibody
  • apoprotein antibody
  • im:7036787 antibody
  • LDLCQ5 antibody
  • LPG antibody
  • wu:fb69a05 antibody
  • zgc:110064 antibody

Protein level used designations for anti-Apolipoprotein E (APOE) Antibodies

apolipoprotein E , ApoE-1 , apo-E , apolipoprotein E3

394678 Xenopus (Silurana) tropicalis
553587 Danio rerio
100136023 Oncorhynchus mykiss
100380959 Xenopus laevis
11816 Mus musculus
348 Homo sapiens
100009337 Oryctolagus cuniculus
25728 Rattus norvegicus
397576 Sus scrofa
100731633 Cavia porcellus
281004 Bos taurus
476438 Canis lupus familiaris
449586 Pan troglodytes
714623 Macaca mulatta
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