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The protein encoded by APOM is an apolipoprotein and member of the lipocalin protein family. Additionally we are shipping Apolipoprotein M Kits (39) and Apolipoprotein M Proteins (29) and many more products for this protein.
Showing 10 out of 176 products:
Human Monoclonal Apolipoprotein M Primary Antibody for ELISA, WB - ABIN394552
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
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Human Monoclonal Apolipoprotein M Primary Antibody for WB - ABIN395065
Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? in Pharmacogenomics 2010
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Human Monoclonal Apolipoprotein M Primary Antibody for IF, WB - ABIN1105422
Xu, Dahlbäck: A novel human apolipoprotein (apoM). in The Journal of biological chemistry 1999
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Human Monoclonal Apolipoprotein M Primary Antibody for ICC, ELISA - ABIN1724662
Xu, Nilsson-Ehle, Ahrén: Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects. in The Journal of nutritional biochemistry 2004
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Human Polyclonal Apolipoprotein M Primary Antibody for IHC (p), IHC - ABIN188728
Mosialou, Zannis, Kardassis: Regulation of human apolipoprotein m gene expression by orphan and ligand-dependent nuclear receptors. in The Journal of biological chemistry 2010
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Human Polyclonal Apolipoprotein M Primary Antibody for ELISA, WB - ABIN451726
Karlsson, Lindqvist, Tagesson, Lindahl: Characterization of apolipoprotein M isoforms in low-density lipoprotein. in Journal of proteome research 2006
liver mRNA levels of apoM and apoA1 (show APOA1 Antibodies) decreased strongly upon sepsis induction.
17beta-estradiol induced up-regulation of apoM in HepG2 cells is through an ER-alpha (show ESR1 Antibodies)-dependent pathway involving ER-alpha (show ESR1 Antibodies) binding element in the promoter of the apoM gene.
A shift in ApoM/sphingosine 1-phosphate between HDL (show HSD11B1 Antibodies)-particles in women with type 1 diabetes mellitus Is associated with impaired anti-inflammatory effects of the ApoM/S1P (show MBTPS1 Antibodies) complex.
ApoM-bound sphingosine-1-phosphate regulates adhesion molecule (show NCAM1 Antibodies) abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.
HDL (show HSD11B1 Antibodies)-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 (show S1PR1 Antibodies) and S1P3 (show S1PR3 Antibodies) receptors on vascular endothelium.
Plasma apoM concentrations are higher in patients with hyperlipidaemia than in healthy controls. Low plasma apoM levels in patients with T2DM are likely caused by diabetes but are not induced by hyperlipidaemia.
The polymorphism C-724del in the promoter region of the apoM gene could confer the risk of T2DM among eastern Han Chinese. Unfortunately, the lowing of plasma apoM levels of C-724del mutant allele carriers compared with the wide-type homozygotes carriers in T2DM patients was not statistically different in present study, so further researchs were needed by enlarging the sample
ApoM rs805296 polymorphism may be a risk factor for developing coronary artery disease [meta-analysis]
ApoM/HDL (show HSD11B1 Antibodies)-C and apoM/apoA1 (show APOA1 Antibodies) ratios could be used as indicators for identification of DN from healthy people and from T2DM patients.
ApoM may be a biomarker of coronary artery disease. ApoM-855 T-->C substitution provides binding sites for AP-2alpha (show TFAP2A Antibodies) and reduces ApoM transcription activity
The study suggests that vascular leakage of albumin (show ALB Antibodies)-sized particles in ApoM deficiency is S1P (show S1PR1 Antibodies)- and S1P1 (show S1PR1 Antibodies)-dependent and this dependency exacerbates the response to inflammatory stimuli.
apoM might facilitate the maintenance of CD4 (show CD4 Antibodies)(+) T-lymphocytes or could modify the T-lymphocytes subgroups in murine spleen
Upon immune stimulation, Apom(-/-) mice developed more severe experimental autoimmune encephalomyelitis, characterized by increased lymphocytes in the central nervous system and breakdown of the blood-brain barrier
LDL receptor (show LDLR Antibodies) and ApoE (show APOE Antibodies) have roles in the clearance of ApoM-associated sphingosine 1-phosphate
ApoM augmented insulin (show INS Antibodies) secretion by maintaining the S1P (show S1PR1 Antibodies) concentration under both in vivo and in vitro conditions.
The present data indicate that the plasma apo-M levels modulate the ability of plasma to mobilize cellular cholesterol, whereas apo-M has no major effect on the excretion of cholesterol into feces.
ApoM can bind oxidized phospholipids, increasing the antioxidant effect of HDL (show HSD11B1 Antibodies).
Results show that apoM, by delivering S1P (show S1PR1 Antibodies) to the S1P (show S1PR1 Antibodies)(1) receptor on endothelial cells, is a vasculoprotective constituent of HDL (show APOA5 Antibodies).
After refolding from inclusion bodies, the crystal structure of apoM (reported here at 2.5 A resolution) displays a novel yet unprecedented seven-stranded beta-barrel structure.
apoM mainly associates with HDL (show HSD11B1 Antibodies) in normal mice but also with the pathologically increased lipoprotein fraction in genetically modified mice; decreased apoM levels in apoA-I (show APOA1 Antibodies)-deficient mice suggest a connection between apoM and apoA-I (show APOA1 Antibodies) metabolism.
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene.
, NG20-like protein
, alternative name: G3a, NG20
, protein G3a
, protein Px