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Exonuclease with activity against single- and double- stranded DNA and RNA. Additionally we are shipping AEN Proteins (5) and AEN Kits (4) and many more products for this protein.
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identification of ISG20L1 as a p53 (show TP53 Antibodies) family target and discovery that modulation of this target can regulate autophagic processes further strengthens the connection between p53 (show TP53 Antibodies) signaling and autophagy
AEN is an important downstream mediator of p53 (show TP53 Antibodies) in apoptosis induction in cancer.
Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity).
apoptosis enhancing nuclease
, interferon stimulated exonuclease gene 20kDa-like 1
, apoptosis-enhancing nuclease
, Interferon-stimulated 20 kDa exonuclease-like 1
, interferon-stimulated 20 kDa exonuclease-like 1
, interferon stimulated exonuclease gene 20-like 1