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The protein encoded by AIP is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. Additionally we are shipping AIP Antibodies (102) and AIP Proteins (11) and many more products for this protein.
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The c.805_825dup allele in AIP, originating from a common ancestor, associates with a severe clinical phenotype of gigantism.
The prevalence of AIP mutations in young Mexican patients with acromegaly is similar to that of European cohorts.
Case Report: truncating AIP mutation, p.W279*, in father/daughter presenting with familial isolated pituitary adenoma.
A modest relationship was found between PPARalpha (show PPARA ELISA Kits) and AIP expression, both being significantly higher in the presence of pre-operative somatostatin (show SST ELISA Kits) analogues in somatotropinoma patients.
The prevalence of AIP(mut (show MUT ELISA Kits)) in Turkish patients was found to be 1 % in sporadic acromegaly in the present study.
No digenism with AIP was identified among patients with sporadic pituitary adenomas.
The aim of this study was to examine mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene
AIP mutations are associated with pituitary gigantism.
in a family of a patient with gigantism, identified a new AIP germline mutation (c.685C>T, p.Q229X) predicted to produce a truncated AIP protein, lacking its biological properties due to the disruption of the C-terminus binding sites for both the chaperones and the client proteins of AIP
a small angle X-ray scattering-derived solution structure of aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1 (show AIPL1 ELISA Kits)) and functional properties of disease-linked AIPL1 (show AIPL1 ELISA Kits)-proline-rich domain mutants
Results demonstrated that Aip inactivation promoted somatotroph tumorigenesis and overproduction of growth hormone (show GH1 ELISA Kits) probably through increased Stat3 (show STAT3 ELISA Kits) activation.
Results provide novel evidence that AIP has an important role in the regulation of cAMP synthesis.
XAP2 exerts a negative effect on ERalpha (show ESR1 ELISA Kits) transcriptional activity and may thus prevent ERalpha (show ESR1 ELISA Kits)-dependent events.
Developmental control of apoptosis by the immunophilin (show FKBP1A ELISA Kits) aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin (show BIRC5 ELISA Kits) protein
Mice with inactivation of aryl hydrocarbon receptor-interacting protein display complete penetrance of pituitary adenomas with aberrant ARNT (show ARNT ELISA Kits) expression.
Data show that AIP is not required for the induction of the Cyp1a1 (show CYP1A1 ELISA Kits) and Cyp1a2 (show CYP1A1 ELISA Kits) genes.
XAP2 hinders importin beta (show KPNB1 ELISA Kits) binding to the mAhR complex and represses the transactivation potential of the AhR (show AHR ELISA Kits) by stabilizing the receptor complex and/or blocking nucleocytoplasmic shuttling of the AhR (show AHR ELISA Kits) complex
PPARalpha (show PPARA ELISA Kits) is in a complex with hsp90 (show HSP90 ELISA Kits) and XAP2, and XAP2 appears to function as a repressor
XAP2 has a role in stabilization of the dioxin receptor (show AHR ELISA Kits)
The role of Xap2 and C-terminal hsp-70 (show HSP70 ELISA Kits) interacting protein on the endogenous Ah receptors expressed in mouse cell lines was determined.
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
aryl hydrocarbon receptor interacting protein
, AH receptor-interacting protein-like
, AH receptor-interacting protein
, HBV X-associated protein 2
, immunophilin homolog ARA9
, aryl-hydrocarbon receptor-interacting protein
, HBV-X associated protein
, immunophilin XAP2