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BCL2-Like 14 (Apoptosis Facilitator) Proteins (BCL2L14)

The protein encoded by BCL2L14 belongs to the BCL2 protein family. Additionally we are shipping BCL2-Like 14 (Apoptosis Facilitator) Antibodies (36) and BCL2-Like 14 (Apoptosis Facilitator) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BCL2L14 79370 Q9BZR8
BCL2L14 66813 Q9CPT0
BCL2L14 500348 Q6AYK4
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Top BCL2-Like 14 (Apoptosis Facilitator) Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BCL2L14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14) Interaction Partners

Human BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14) interaction partners

  1. Data indicate that LRP6 (show LRP6 Proteins), BCL2L14, DUSP16 (show DUSP16 Proteins), CREBL2 (show CREBL2 Proteins), and CDKN1B (show CDKN1B Proteins) were involed in centromeric (12p11.21-12p13.2) deletion in ETV6 (show ETV6 Proteins)-RUNX1 (show RUNX1 Proteins) B-cell precursor acute lymphoblastic leukemia (BCP (show OPN1SW Proteins)-ALL).

  2. Single nucleotide polymorphism in BCL2L14 is associated with lung cancer.

  3. prior knockdown of Bcl-G expression ablates the stimulation of basal apoptosis by FAU (show FAU Proteins), consistent with an essential downstream role for Bcl-G, itself a candidate tumour suppressor, in mediating the apoptosis regulatory role of FAU (show FAU Proteins).

  4. siRNA downregulation of Bcl-G inhibited breast cancer cell apoptosis. Adding an siRNA against Fau (show FAU Proteins) revealed control of Bcl-G by Fau (show FAU Proteins). The most important factors controlling Bcl-G are post-translational modification by Fau (show FAU Proteins) & MELK (show MELK Proteins), not transcription rate.

  5. There was no somatic mutation of BH3 domains of Bad, Bmf (show BMF Proteins) and Bcl-G genes in transitional cell carcinoma samples. The data presented here indicate that BH3 domain mutation of these genes is rare in TCCs and may not contribute to the pathogenesis of TCCs.

  6. the kinase activity of MELK (show MELK Proteins) is likely to affect mammary carcinogenesis through inhibition of the pro-apoptotic function of Bcl-GL

  7. data presented here indicate that BH3 domain mutation of the proapoptotic genes Bad, Bmf (show BMF Proteins) and Bcl-G is rare in laryngeal squamous cell carcinoma and may not contribute to the apoptosis-resistance mechanisms of laryngeal squamous cell carcinoma

  8. JAB1 (show COPS5 Proteins) is involved in the regulation of mitochondrial apoptotic pathway through specific interaction with BclGs.

  9. Increased BclG(L) expression may contribute to the aberrant CD4 (show CD4 Proteins)+ T cell apoptosis which causes an inappropriate immune response and impaired homeostasis in systemic lupus erythematosus.

Mouse (Murine) BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14) interaction partners

  1. CD3 (show CD3E Proteins)/CD28 (show CD28 Proteins)-inducible MNSFbeta (show FAU Proteins)-Bcl-G complex may be involved in the regulation of T cell function and survival.

  2. Bcl-G is expressed highly in mature spermatids in the testis, CD8 (show CD8A Proteins)(+) conventional dendritic cells (DCs) in hematopoietic tissues and diverse epithelial cell types, including those lining the gastrointestinal and respiratory tracts.

BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.

Gene names and symbols associated with BCL2L14

  • BCL2-like 14 (apoptosis facilitator) (BCL2L14)
  • BCL2-like 14 (apoptosis facilitator) (Bcl2l14)
  • Bcl2-like 14 (apoptosis facilitator) (Bcl2l14)
  • 4930452K23Rik protein
  • 4933405K19Rik protein
  • 9030625M01Rik protein
  • AI429211 protein
  • Bclg protein

Protein level used designations for BCL2L14

apoptosis facilitator Bcl-2-like protein 14 , apoptosis regulator BCL-G , bcl2-L-14

GENE ID SPECIES
79370 Homo sapiens
66813 Mus musculus
500348 Rattus norvegicus
508365 Bos taurus
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