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anti-BCL2-Like 2 (BCL2L2) Antibodies

BCL2L2 encodes a member of the BCL-2 protein family. Additionally we are shipping BCL2-Like 2 Proteins (20) and BCL2-Like 2 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCL2L2 599 Q92843
BCL2L2 12050 P70345
BCL2L2 60434  
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Top anti-BCL2-Like 2 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Bcl-w BH3 domain Pab (ABIN388097) in HL-60 cell lysate. Bcl-w BH3 domain (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Western blot analysis of Bcl-w3 (arrow) using rabbit polyclonal Bcl-w BH3 Domain Antibody (ABIN388097). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the BCL2L2 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from COLO cells, using BCLW Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using BCLW Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rat Un-conjugated WB Western blot analysis for Bcl-w. Lysates from mouse brain tissue were probed with the rat anti- Bcl-w antibody at concentrations of 0.5 µg/mL (lane 1), 0.25 µg/mL (lane 2), and 0.125 µg/mL (lane 3). Bcl-w may be observed to be migrating in a range from 21-25 kDa. 50 μg Log in to see 5 to 6 Days
$474.78
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Bcl2l2 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- BCL2L2 antibody, IHC(P) IHC(P): Human Rectal Cancer Tissue Anti- BCL2L2 antibody,  Western blotting All lanes: Anti BCL2L2 () at 0.5ug/ml WB: HELAWhole Cell Lysate at 40ug Predicted bind size: 21KD Observed bind size: 21KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot (WB) analysis of Bcl-w antibody in extracts from COLO cell 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of BCLW staining in HL60 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of BCLW staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

BCL2L2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-BCL2-Like 2 Antibodies

  1. Human Polyclonal BCL2L2 Primary Antibody for EIA, IHC (p) - ABIN356814 : Denisov, Madiraju, Chen, Khadir, Beauparlant, Attardo, Shore, Gehring: Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN356814

  2. Human Monoclonal BCL2L2 Primary Antibody for WB - ABIN967292 : Adams, Cory: The Bcl-2 protein family: arbiters of cell survival. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 5 references for ABIN967292

  3. Human Polyclonal BCL2L2 Primary Antibody for IHC (p), WB - ABIN388097 : Hinds, Lackmann, Skea, Harrison, Huang, Day: The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity. in The EMBO journal 2003 (PubMed)
    Show all 4 references for ABIN388097

  4. Human Polyclonal BCL2L2 Primary Antibody for IF, ELISA - ABIN1534430 : Gibson, Holmgreen, Huang, Bernard, Copeland, Jenkins, Sutherland, Baker, Adams, Cory: bcl-w, a novel member of the bcl-2 family, promotes cell survival. in Oncogene 1996 (PubMed)

More Antibodies against BCL2-Like 2 Interaction Partners

Human BCL2-Like 2 (BCL2L2) interaction partners

  1. Genetic and pharmacological inhibition of BCL-W and BCL-XL (show BCL2L1 Antibodies) causes directed elimination of senescent cells.

  2. Data show that BCL2-like 2 protein (BCL2L2) is a direct target of micrRNA miR (show MLXIP Antibodies)-29b.

  3. these results indicate that miR (show MLXIP Antibodies)-335 acts as a novel tumor suppressor to regulate ccRCC cell proliferation and invasion through downregulation of BCL-W expression.

  4. miR (show MLXIP Antibodies)-15a acts as a tumor suppressor in NSCLC by directly targeting BCL2L2 and may serve as a potential diagnostic biomarker and therapeutic target for NSCLC.

  5. The crystal structures of BCL-W and BCL-XL (show BCL2L1 Antibodies), along with cellular, studies reveal critical features of the BH3 domains of pro-survival proteins that distinguish them functionally from their pro-apoptotic counterparts.

  6. over-expression of miR (show MLXIP Antibodies)-195 sensitized resistant cells to DOX and enhanced cell apoptosis activity, all of which can be partly rescued by BCL2L2 siRNA and cDNA expression

  7. A structural basis for a conserved binding mechanism between p53DBD and the anti-apoptotic Bcl-2 (show BCL2 Antibodies) family proteins.

  8. Bcl-w-induced Sp1 (show PSG1 Antibodies) activation is a potential marker for aggressiveness of glioblastoma multiforme.

  9. HDMF inhibits Bcl-w-induced neurosphere formation and the expression of glioma stem cell markers, such as Musashi (show MSI1 Antibodies), Sox-2 (show SOX2 Antibodies) and c-myc (show MYC Antibodies).

  10. Crystal structure of human BCL-W in complex with different DARPins is virtually identical to the ligand-free conformation of its closest relative BCL-XL (show BCL2L1 Antibodies).

Mouse (Murine) BCL2-Like 2 (BCL2L2) interaction partners

  1. Genetic and pharmacological inhibition of BCL-W and BCL-XL (show BCL2L1 Antibodies) causes directed elimination of senescent cells.

  2. NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies)/p52 (show GTF2H4 Antibodies) signaling mediated the effects of GDNF (show GDNF Antibodies) on Bcl-2 (show BCL2 Antibodies) and Bcl-w expressions

  3. Target-derived neurotrophins coordinate transcription of the antiapoptotic gene bclw with transport of bclw mRNA to the axon, and thereby prevent axonal degeneration in rat and mouse sensory neurons.

  4. By using human cancer cells and mouse embryonic fibroblasts, the study shows that Bcl-w functions in the mitochondria to increase the levels of reactive oxygen species (ROS (show ROS1 Antibodies)), which subsequently stimulates the invasion-promoting signaling pathway.

  5. Bcl-2 (show BCL2 Antibodies), Bcl-x(L (show BCL2L1 Antibodies)) and Bcl-w have only minor roles in thymic lymphoma development elicited by defects in p53 (show TP53 Antibodies), and this may indicate that Mcl-1 (show MCL1 Antibodies) and/or A1 may feature more prominently in this process.

  6. Induction of autocrine Bcl-w signaling through pericytes promoting endothelial cell survival is associated with melanoma development.

  7. Bcl-w(-/-) sensory neurons exhibit mitochondrial abnormalities, including alterations in axonal mitochondrial size, axonal mitochondrial membrane potential, and cellular ATP levels.

  8. Bcl-x(L) and Bcl-w target protein phosphatase 1alpha to Bad

  9. Bcl-2 (show BCL2 Antibodies), Bcl-w, and Bax (show BAX Antibodies) act in a redundant manner in regulating granulocyte survival and death

  10. amino acid and base sequences of c98 gene (bcl-2 (show BCL2 Antibodies) homolog) expressed in newborn epidermal keratinocytes treated with IGF-1 (show IGF1 Antibodies)

Cow (Bovine) BCL2-Like 2 (BCL2L2) interaction partners

  1. Chromosome mapping of BCL2L2 gene in cows.

BCL2-Like 2 (BCL2L2) Antigen Profile

Protein Summary

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Gene names and symbols associated with anti-BCL2-Like 2 (BCL2L2) Antibodies

  • Bcl2-like 2 (bcl2l2) antibody
  • BCL2-like 2 (BCL2L2) antibody
  • BCL2-like 2 (Bcl2l2) antibody
  • Bcl2-like 2 (Bcl2l2) antibody
  • AW048834 antibody
  • Bcl-w antibody
  • BCL-WEL antibody
  • BCL-WS antibody
  • BCL2-L-2 antibody
  • BCL2L2 antibody
  • Bclw antibody
  • c98 antibody
  • Gtrgal2 antibody
  • Gtrosa41 antibody
  • PPP1R51 antibody

Protein level used designations for anti-BCL2-Like 2 (BCL2L2) Antibodies

Bcl2-like 2 , BCL2-like 2 , apoptosis regulator BCL-W , bcl-2-like protein 2 , protein phosphatase 1, regulatory subunit 51 , apoptosis regulator Bcl-W , bcl2-L-2

GENE ID SPECIES
496475 Xenopus (Silurana) tropicalis
768265 Felis catus
599 Homo sapiens
12050 Mus musculus
490611 Canis lupus familiaris
60434 Rattus norvegicus
767601 Bos taurus
Selected quality suppliers for anti-BCL2-Like 2 (BCL2L2) Antibodies
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