BCL2L2 antibody (AA 131-180)

Catalog No. ABIN1534430

The Rabbit Polyclonal anti-BCL2L2 antibody (ABIN1534430) specifically detects BCL2L2 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BCL2L2 antibody (AA 131-180) (ABIN1534430)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BCL2L2 Antibody

Binding Specificity: AA 131-180

Purpose: Bcl-w Antibody

Specificity: Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BCLW. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: BCLW

Background:

Synonyms: BCL2L2, BCLW, KIAA0271, Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010],

Gene Name: BCL2L2

Protein Name: Bcl-2-like protein 2

Molecular Weight: 20 kDa

Gene ID: 599

OMIM: 601931

UniProt: Q92843