BCL2L2 antibody (Middle Region)

Catalog No. ABIN3042693

Product Details anti-BCL2L2 Antibody

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Binding Specificity: AA 74-88, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Bcl-2-like protein 2(BCL2L2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: SAQQRFTQVS DELFQ

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Bcl-2-like protein 2(BCL2L2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2-like 2
Protein Name: Bcl-2-like protein 2(Bcl2-L-2)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human BCL2L2(74-88aa SAQQRFTQVSDELFQ), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for BCL2L2 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: BCL2L2 (BCL2L2 Products)

Synonyms: bcl2l2 antibody, BCL2L2 antibody, BCL-W antibody, BCL2-L-2 antibody, BCLW antibody, PPP1R51 antibody, AW048834 antibody, Bcl-w antibody, Gtrgal2 antibody, Gtrosa41 antibody, bclw antibody, c98 antibody, BCL-WEL antibody, BCL-WS antibody, Bclw antibody, bcl-w antibody, bcl2l2-a antibody, bcl2l2-b antibody, xr1 antibody, BCL2 like 2 antibody, BCL2-like 2 antibody, BCL2 like 12 antibody, Bcl2-like 2 antibody, bcl-2-like protein 2 antibody, BCL2-like 2 L homeolog antibody, BCL2L2 antibody, bcl2l2 antibody, BCL2L12 antibody, Bcl2l2 antibody, LOC100154044 antibody, LOC100345100 antibody, bcl2l2.L antibody

Background: Bcl-2-like protein 2 is a protein that in humans is encoded by the BCL2L2 gene. This gene encodes a pro-survival(anti-apoptotic) member of the bcl-2 protein family. Its gene is mapped to human chromosome 14q11.2-q12. In all, it has got 193 amino acids. Generally speaking, the BCL2 can be found in brain, colon and salivary gland. Acting as the anti- and pro-apoptotic regulators, it has played a vital role in reducing the cell apoptosis under cytotoxic conditions.

Synonyms: Apoptosis regulator Bcl-W

UniProt: Q92843