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anti-BCL2-Related Ovarian Killer (BOK) Antibodies

The protein encoded by BOK belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Additionally we are shipping BOK Kits (6) and BOK Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BOK 666 Q9UMX3
BOK 29884 Q792S6
BOK 51800 O35425
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Top anti-BOK Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB BOK Antibody (N-term) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the BOK antibody detected the BOK protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Bok BH3 domain Pab (ABIN388103) in HL-60 cell lysate. Bok BH3 domain (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB BOK Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BOK antibody detected the BOK protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Rat Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

BOK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus)


Mouse (Murine) ,
,

Top referenced anti-BOK Antibodies

  1. Human Polyclonal BOK Primary Antibody for EIA, WB - ABIN950672 : Stein, Hua, Lee, Ho, Leow, Toga, Saykin, Shen, Foroud, Pankratz, Huentelman, Craig, Gerber, Allen, Corneveaux, Dechairo, Potkin, Weiner, Thompson,: Voxelwise genome-wide association study (vGWAS). in NeuroImage 2010 (PubMed)
    Show all 5 references for ABIN950672

  2. Human Polyclonal BOK Primary Antibody for IHC (p), WB - ABIN388103 : Hsu, Kaipia, McGee, Lomeli, Hsueh: Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 4 references for ABIN388103

  3. Human Polyclonal BOK Primary Antibody for EIA, IHC (p) - ABIN356820 : Yakovlev, Di Giovanni, Wang, Liu, Stoica, Faden: BOK and NOXA are essential mediators of p53-dependent apoptosis. in The Journal of biological chemistry 2004 (PubMed)

  4. Human Polyclonal BOK Primary Antibody for EIA, IHC (p) - ABIN1450152 : Lockshin, Osborne, Zakeri: Cell death in the third millennium. in Cell death and differentiation 2000 (PubMed)

More Antibodies against BOK Interaction Partners

Human BCL2-Related Ovarian Killer (BOK) interaction partners

  1. Data suggest that hypoxia-induced expression of BOK in placental cells is regulated via promoter region, hypoxia-response element, and binding of hypoxia-inducible factors (HIF1A (show HIF1A Antibodies), HIF2A/EPAS1 (show EPAS1 Antibodies), HIF1B/ARNT (show ARNT Antibodies)) but is not affected by its antisense transcript.

  2. First evidence for a key role of the BOK-MCL1 (show MCL1 Antibodies) system in regulating autophagy in the human placenta, whereby an adverse environment as seen in preeclampsia tilts the BOK-MCL1 (show MCL1 Antibodies) balance toward the build-up of isoforms that triggers placental autophagy.

  3. Bok may govern IP3R (show ITPR1 Antibodies) cleavage and activity during apoptosis.

  4. The results suggest important roles for Bok and Bcl-X(L (show BCL2L1 Antibodies)) in human ovarian development, follicle maturation and apoptosis.

  5. Data conclude that Mtd (show MT1E Antibodies)-L functions to regulate trophoblast cell proliferation during early placentation and that the elevated levels of Mtd (show MT1E Antibodies) found in PE may contribute to increased trophoblast proliferation.

  6. BOK and NOXA (show PMAIP1 Antibodies) are essential mediators of p53 (show TP53 Antibodies)-dependent apoptosis

  7. A novel Mtd/BOK splice isoform is responsible for trophoblast cell death in pre-eclampsia.

  8. Studies showed that hBok was distributed in both the cytosol and intracellular membranes of healthy cells.

  9. a link between the apoptotic activity and nuclear localization of a pro-apoptotic Bok

  10. Bok represents a cell cycle-regulated pro-apoptotic member of the Bcl-2 (show BCL2 Antibodies) family

Mouse (Murine) BCL2-Related Ovarian Killer (BOK) interaction partners

  1. Bok controls neuronal Ca(2 (show CA2 Antibodies)+) homeostasis and bioenergetics in seizure-induced neuronal injury.

  2. Study reports that BCL-2 (show BCL2 Antibodies) ovarian killer (BOK) is a bona fide yet unconventional effector of mitochondrial outer membrane permeabilization that can trigger apoptosis in the absence of both BAX (show BAX Antibodies) and BAK (show BAK1 Antibodies).

  3. findings support a selective and distinguishing role for BOK in regulating the apoptotic response to ER stress, revealing--to our knowledge--the first bona fide apoptotic defect linked to Bok deletion

  4. BOK-deficient mice have no readily discernible abnormalities, and its function therefore remains unresolved.

  5. Bok may govern IP3R (show ITPR1 Antibodies) cleavage and activity during apoptosis.

  6. two proapoptotic Bcl-2 family members Bok and Noxa/Pmaip are directly transcriptionally induced by activated MAL and upon activation of the actin-MAL-SRF pathway

  7. Bok protein have a role that largely overlaps with that of other members of the Bcl-2 (show BCL2 Antibodies) family, or may have a function restricted to specific stress stimuli and/or tissues.

  8. Bok represents a cell cycle-regulated pro-apoptotic member of the Bcl-2 (show BCL2 Antibodies) family

BOK Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Gene names and symbols associated with BOK

  • BCL2-related ovarian killer b (bokb) antibody
  • BCL2-related ovarian killer a (boka) antibody
  • BCL2-related ovarian killer (BOK) antibody
  • BCL2-related ovarian killer (LOC100220512) antibody
  • BCL2-related ovarian killer (Bok) antibody
  • BCL2-related ovarian killer protein (Bok) antibody
  • AI847676 antibody
  • AU021146 antibody
  • BCL2L9 antibody
  • bok antibody
  • Bok-BH3 antibody
  • BOKL antibody
  • matador antibody
  • mtd antibody
  • zgc:64041 antibody
  • zgc:100979 antibody

Protein level used designations for BOK

bcl-2-related ovarian killer protein homolog B , zBok2 , bcl-2-related ovarian killer protein homolog A , zBok1 , BCL2-related ovarian killer , Bcl-2-related ovarian killer , bcl-2-like protein 9 , bcl-2-related ovarian killer protein , bcl2-L-9 , hBOK , apoptosis activator Mtd , protein matador

GENE ID SPECIES
394160 Danio rerio
445218 Danio rerio
701430 Macaca mulatta
768266 Felis catus
100220512 Taeniopygia guttata
666 Homo sapiens
504851 Bos taurus
29884 Rattus norvegicus
395445 Gallus gallus
51800 Mus musculus
Selected quality suppliers for anti-BOK (BOK) Antibodies
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