Baculoviral IAP Repeat-Containing 7 Proteins (BIRC7)

The protein encoded by BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. Additionally we are shipping Baculoviral IAP Repeat-Containing 7 Antibodies (169) and Baculoviral IAP Repeat-Containing 7 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BIRC7 107768  
BIRC7 79444 Q96CA5
Rat BIRC7 BIRC7 296468  
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Top Baculoviral IAP Repeat-Containing 7 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,999.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$4,009.50
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

BIRC7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
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Top referenced Baculoviral IAP Repeat-Containing 7 Proteins

  1. Human BIRC7 Protein expressed in Escherichia coli (E. coli) - ABIN667709 : Ashhab, Alian, Polliack, Panet, Ben Yehuda: Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. in FEBS letters 2001 (PubMed)
    Show all 2 references for 667709

More Proteins for Baculoviral IAP Repeat-Containing 7 (BIRC7) Interaction Partners

Mouse (Murine) Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Proteins) and MMP-2 (show MMP2 Proteins)/-9. Its silencing resulted in the prevention of xenograft tumor formation.

  2. Birc7 is a late fiber gene of the mouse lens. Its expression in cells bordering the OFZ is consistent with a role in organelle degradation, a process in which the ubiquitin proteasome pathway has been implicated previously.

  3. ML-IAP is dispensable for both normal mouse development and ocular homoeostasis.

Human Baculoviral IAP Repeat-Containing 7 (BIRC7) interaction partners

  1. Further experiments confirmed the induction of cell apoptosis and suppression of cell proliferation by anti-MM scFv-tP in LiBr cells, along with efficient silence of Livin gene both in vitro and in vivo. Altogether, our findings provide a feasible approach to transport Livin small interfering RNA to malignant melanoma cells which would be a new therapeutic strategy for combating malignant melanoma

  2. MicroRNA-214 inhibits the osteogenic differentiation of human osteoblasts through the direct regulation of BIRC7.

  3. the results of the present study suggested that Livin may enhance tumorigenesis by modulating the mitogenactivated/Akt (show AKT1 Proteins) signaling pathways in human HSCC.

  4. Positive BIRC7 expression and negative KLF4 (show KLF4 Proteins) expression are associated with the progression of PDAC and poor prognosis in patients with PDAC.

  5. High expression of BIRC7 is associated with drug resistance in Renal cell carcinoma (show MOK Proteins).

  6. Data show that cylindromatosis (CYLD (show CYLD Proteins)) overexpression and livin knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (show BLNK Proteins)) cells.

  7. The apoptosisinducing effects of livin and surivin knockdown were investigated using a Hoechst staining kit.

  8. Expression of livin, survivin (show BIRC5 Proteins) and caspase-3 (show CASP3 Proteins) are closely related to the occurrence and development of prostatic cancer.

  9. Our results suggested the important role of Livin and its partner molecule in the process of VSV treatment

  10. Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Proteins) and MMP-2 (show MMP2 Proteins)/-9. Its silencing resulted in the prevention of xenograft tumor formation.

Baculoviral IAP Repeat-Containing 7 (BIRC7) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Gene names and symbols associated with BIRC7

  • baculoviral IAP repeat-containing 5-like (Birc5l)
  • baculoviral IAP repeat containing 7 (BIRC7)
  • baculoviral IAP repeat-containing 7 (birc7)
  • baculoviral IAP repeat containing 7 (birc7)
  • baculoviral IAP repeat-containing 7 (Birc7)
  • baculoviral IAP repeat-containing 7 (livin) (Birc7)
  • E130019N06 protein
  • EIAP/XLX protein
  • KIAP protein
  • Livin protein
  • ML-IAP protein
  • MLIAP protein
  • RGD1562883 protein
  • RNF50 protein
  • TIAP2 protein
  • xEIAP protein
  • XLX protein
  • zgc:165605 protein

Protein level used designations for BIRC7

baculoviral IAP repeat-containing 5-like , baculoviral IAP repeat-containing 7 , baculoviral IAP repeat-containing 7 (livin) , E3 ubiquitin-protein ligase EIAP , Embryonic/Egg IAP , baculoviral IAP repeat-containing protein 7 , RING finger protein 50 , kidney inhibitor of apoptosis protein , livin inhibitor of apoptosis , melanoma inhibitor of apoptosis protein

GENE ID SPECIES
107768 Mus musculus
419239 Gallus gallus
485969 Canis lupus familiaris
514508 Bos taurus
697671 Macaca mulatta
100073331 Danio rerio
100127811 Xenopus (Silurana) tropicalis
79444 Homo sapiens
296468 Rattus norvegicus
329581 Mus musculus
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