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anti-Bone Morphogenetic Protein 4 (BMP4) Antibodies

The protein encoded by BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. Additionally we are shipping BMP4 Kits (107) and BMP4 Proteins (68) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BMP4 652 P12644
BMP4 12159 P21275
BMP4 25296  
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Top anti-BMP4 Antibodies at antibodies-online.com

Showing 10 out of 211 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Bmp4 Antibody (G20) (ABIN388454) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane).This demonstrates the Bmp4 antibody detected the Bmp4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB BMP4 Antibody  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the BMP4 antibody detected the BMP4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Chicken Rabbit Un-conjugated IHC, WB   100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated DB, EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, WB WB Image Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using BMP4, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, WB Anti-BMP4 mouse monoclonal antibody (ABIN2452355) immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY BMP4 (RC219979) BMP4 antibody (6B7) at 1:100000 dilution + Recombinant human BMP4 100 μL Log in to see 2 to 3 Days
$423.50
Details

BMP4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BMP4 Antibodies

  1. Human Monoclonal BMP4 Primary Antibody for WB - ABIN659071 : Kupfer, Anderson, Hooker, Skol, Kittles, Keku, Sandler, Ellis: Genetic heterogeneity in colorectal cancer associations between African and European americans. in Gastroenterology 2010 (PubMed)
    Show all 4 references for ABIN659071

  2. Human Polyclonal BMP4 Primary Antibody for DB, EIA - ABIN492827 : Peng: The TGF-beta superfamily and its roles in the human ovary and placenta. in Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2003 (PubMed)
    Show all 4 references for ABIN492827

  3. Human Monoclonal BMP4 Primary Antibody for ELISA, WB - ABIN968986 : Oida, Iimura, Maruoka, Takeda, Sasaki: Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library. in DNA sequence : the journal of DNA sequencing and mapping 1995 (PubMed)
    Show all 3 references for ABIN968986

  4. Human Polyclonal BMP4 Primary Antibody for IHC (p), WB - ABIN388454 : Sorescu, Sykes, Weiss, Platt, Saha, Hwang, Boyd, Boo, Vega, Taylor, Jo: Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN388454

  5. Chicken Polyclonal BMP4 Primary Antibody for IHC, WB - ABIN223638 : Ni, Qiu, Rezvan, Kwon, Nam, Son, Visvader, Jo: Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow. in Blood 2010 (PubMed)
    Show all 2 references for ABIN223638

  6. Human Polyclonal BMP4 Primary Antibody for WB - ABIN2789354 : Ganti, Hunt, Parapuram, Hunt: Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells. in Investigative ophthalmology & visual science 2007 (PubMed)

More Antibodies against BMP4 Interaction Partners

Zebrafish Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Structures of Bmp2a (show BMP2 Antibodies), Bmp2b, Bmp4 and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.

  2. FGF signaling in establishment of the developmental hematopoietic stem cell niche occurs via inhibition of bmp4 transcription, and activation of bmp antagonists, nog2 and grem1a (show GREM1 Antibodies).

  3. Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development.

  4. BMP2b signaling in zebrafish embryos substantially decreases emergence of lymphatic endothelial cells.

  5. Data show that BMP2B protein is expressed in a gradient as early as blastula stages.

  6. we identify a previously unappreciated role for the Nodal-transcription factor FoxH1 in mediating cell responsiveness to Bmp further linking the control of these two pathways in the heart

  7. The Bmp2b mutants and mosaic loss-of-function experiments reveal that BMP acts as a repressor of eye-field fate through inhibition of its key transcription factor Rx3, thereby protecting the future telencephalon from acquiring eye identity.

  8. bmp2b is involved in dorsal retina initiation, acting upstream of gdf6a.

  9. Results show that BMP2b down-regulates fshr (show FSHR Antibodies) while up-regulating lhr (show LHCGR Antibodies).

  10. These data reveal a novel role for LRP1 (show LRP1 Antibodies) in the regulation of Bmp4 signaling by regulating receptor complex endocytosis.

Xenopus laevis Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Data indicate that bone morphogenetic protein (BMP) signaling is essential for erythroid differentiation, and in the absence of BMP signaling, precursor cells adopt an endothelial cell (EC) fate.

  2. Osr1 (show OSR1 Antibodies)/Osr2 normally repress bmp4 expression in the lateral plate mesoderm prior to respiratory specification.

  3. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4.

  4. PIAS (show PIAS1 Antibodies) proteins have differential ability to regulate signals from the growth factors activin (show Actbeta Antibodies), bone morphogenetic protein 4 (BMP4), and Wnt8 (show WNT8A Antibodies).

  5. Data show that PV.1A undergoes combinatorial regulation during early Xenopus development as both the direct target of BMP-4 signaling and as the direct and indirect target of positive and negative regulatory factors.

  6. BMP inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.

  7. Data suggest that the feedback inhibitors BAMBI (show BAMBI Antibodies), SMAD6 (show SMAD6 Antibodies), and SMAD7 (show SMAD7 Antibodies) expand the dynamic BMP4 signaling range essential for proper embryonic patterning and reduce interindividual phenotypic and molecular variability in Xenopus embryos.

  8. limits homeobox (show PRRX1 Antibodies) gene expression in the organiser/non-organiser direction

  9. X-epilectin expression is down-regulated by Noggin (show NOG Antibodies) and tBR and that this effect is inhibited by BMP4 over-expression

  10. BMP4-dependent expression of Xenopus Grainyhead-like 1 (show GRHL1 Antibodies) has a critical role in epidermal differentiation

Horse (Equine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. BMP4 signaling plays a role in the regulation of terminal differentiation of primary equine trophoblast cells via activation of the SMAD1 (show SMAD1 Antibodies)/5 pathway

Human Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. we have for the first time characterized the BMP4-induced miRNA expression profiles in breast cancer cell lines, showing that induced miRNAs contribute to the fine-tuning of proliferation and migration phenotypes.

  2. BMP4 caused a trend towards accelerated metastasis formation, especially in bone. More work is needed to uncover the long-term effects of BMP4 and the clinical relevance of these findings.

  3. BMP4 is a direct thyroid hormone (show PTH Antibodies) target and is involved in a positive autoregulatory feedback loop that modulates thyroid hormone (show PTH Antibodies) signaling

  4. An up-regulated expression of BMP-4 and BMPR-II (show BMPR2 Antibodies) was observed in the peripheral blood of breast cancer patients especially in the advanced-stage of the disease. Moreover, BMP-4 and BMPR-II (show BMPR2 Antibodies) expressions were found to be correlated

  5. PDGF (show PDGFA Antibodies)-AA impairs endothelium-dependent vasodilation and PDGF (show PDGFA Antibodies)-AA mediates BMP4-induced adverse effect on endothelial cell function through SMAD1 (show GARS Antibodies)/5- and SMAD4 (show SMAD4 Antibodies)-dependent mechanisms.

  6. BMP4 gene is involved in the ATO regulation of adipogenic and osteogenic differentiation balance, which provides a new target for the treatment of AA

  7. Overexpression of the BMP4/SMAD4 (show SMAD4 Antibodies)/SMAD5 (show SMAD5 Antibodies) signaling pathway could predict poor clinical outcome in skull base chordomas, suggesting activation of this pathway is involved in chordoma pathogenesis.

  8. HIF-1alpha (show HIF1A Antibodies) knockdown attenuated hypoxia-induced BMP4 expression and knockdown of either HIF-1alpha (show HIF1A Antibodies) or BMP4 abolished hypoxia-induced TRPC expression and basal [Ca(2 (show CA2 Antibodies)+)]i.

  9. The effect of TGF-beta1 (show TGFB1 Antibodies) and BMP-4 on bone marrow-derived stem cell morphology on a novel bioabsorbable nanocomposite material.

  10. Suggest that hypermethylation of ACP1 (show ACP1 Antibodies), BMP4, and TSPYL5 (show TSPYL5 Antibodies) are common events in HCC (show FAM126A Antibodies) and could be used as potentially detectable biomarkers in HCC (show FAM126A Antibodies) tissues.

Mouse (Murine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Ino80 (show INO80 Antibodies) represses Bmp4 expression during embryonic stem cell differentiation.

  2. only BMP7 (show BMP7 Antibodies), not BMP2 (show BMP2 Antibodies) or BMP4, is necessary for interdigital programmed cell death

  3. Report phenotype of BMP2/4 double knockout osteoblast cell line.

  4. PDGF (show PDGFA Antibodies)-AA impairs endothelium-dependent vasodilation and PDGF (show PDGFA Antibodies)-AA mediates BMP4-induced adverse effect on endothelial cell function through SMAD1 (show SMAD1 Antibodies)/5- and SMAD4 (show SMAD4 Antibodies)-dependent mechanisms.

  5. BMP4 has a role in inducing NOX1 (show NOX1 Antibodies)-dependent eNOS (show NOS3 Antibodies) uncoupling in T2DM, which may promote development of novel therapeutics restoring endothelial function in T2DM

  6. resveratrol markedly amplifies BMP4induced OPG (show TNFSF11 Antibodies) mRNA expression.

  7. BMP4 promotes activation of FGF7 (show FGF7 Antibodies) and FGF10 (show FGF10 Antibodies) signaling, leading to an increase in proliferative basal cell population in developing skin.

  8. calbindin1 in rat primary islet cells reduced glucose-stimulated insulin (show INS Antibodies) secretion (GSIS), and the effect of BMP4 on GSIS was lost in islets from calbindin1 (Calb1 (show CALB1 Antibodies)) knockout mice

  9. the dental follicle participates in alveolar bone formation and Bmp2/4 appears to accelerate alveolar bone development

  10. Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling modulates corneal epithelium stratification via inhibition of Bmp4 during mouse development.

Cow (Bovine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. The BMP2/4 ligand and receptor system presides within bovine trophectoderm prior to uterine attachment. BMP4 negatively impacts CT1 (show SLC6A8 Antibodies) cell growth

  2. BMP4 during maturation increased the proportion of Oct-4 (show POU5F1 Antibodies) positive cells in parthenogenic embryos. BMP4 is implicated in bovine oocytes maturation and embryo development.

  3. analysis of polymorphic CA microsatellites in the third exon of the bovine BMP4 gene

  4. concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than in oocyte maturation

  5. Data report that BMP-7 (show BMP7 Antibodies) suppresses granulosa cell apoptosis by inhibiting the release of caspase-activated DNase (CAD (show DFFB Antibodies)) via a mechanism which does not appear to be associated with the mitochondrial pathway, whereas BMP-4 inhibits the release of CAD (show CAD Antibodies).

  6. Heat shock protein 70 (show HSP70 Antibodies) enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein (show MGP Antibodies).

Goat Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. A microsatellite (ACn (show ACIN1 Antibodies)) was identified in the 3' UTR (show UTS2R Antibodies) of BMP4 gene.Prolificacy associated microsatellite (AC19 (show POLR1D Antibodies)) was detected in Indian goats.

Pig (Porcine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. paracrine signals from the embryo, represented by FGF4 (show FGF4 Antibodies) and BMP4, induce a response in the trophoblast prior to the extensive elongation.

  2. The structure of porcine BMP4 gene is highly conservative with other mammalian BMP4 genes, but some differences may be present in the regulation of gene expression.

  3. Altered shear stress stimulates upregulation of endothelial VCAM-1 (show VCAM1 Antibodies) and ICAM-1 (show ICAM1 Antibodies) in a BMP-4- and TGF-beta1 (show TGFB1 Antibodies)-dependent pathway.

Rabbit Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. The TM-induced characteristic changes in the expression pattern of Hoxa11 (show HOXA11 Antibodies) and Bmp4 on GDs (show PAEP Antibodies) 10 and/or 11 were not noted.

  2. BMP4 is expressed peripherally in hypoblast and epiblast and in the mesoderm at the posterior pole of the embryonic disc.

  3. Data show that BMP-2 (show BMP2 Antibodies), BMP-4, and BMP-7 (show BMP7 Antibodies), noggin (show NOG Antibodies), and chordin (show CHRD Antibodies) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.

  4. Both of the adenovirus-containing bone morphogenetic protein transduced MSCs expressed BMP4 mRNA and protein and underwent osteogenic differentiation.

BMP4 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene names and symbols associated with BMP4

  • bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (bmp4-a) antibody
  • bone morphogenetic protein 4 (BMP4) antibody
  • Bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (LOC100286408) antibody
  • bone morphogenetic protein 2b (bmp2b) antibody
  • bone morphogenetic protein 4 (bmp4-b) antibody
  • bone morphogenetic protein 4 (Bmp4) antibody
  • bmp-2 antibody
  • BMP-4 antibody
  • bmp2 antibody
  • bmp2-4 antibody
  • Bmp2b antibody
  • Bmp2b-1 antibody
  • Bmp2b1 antibody
  • BMP4 antibody
  • BOMPR4A antibody
  • cb670 antibody
  • MCOPS6 antibody
  • OFC11 antibody
  • XBMP-4 antibody
  • xbmp4 antibody
  • zbmp-2 antibody
  • zbmp-4 antibody
  • zbmp2 antibody
  • zgc:100779 antibody
  • ZYME antibody

Protein level used designations for BMP4

etID309887.17 , bone morphogenetic protein-4 , bone morphogenetic protein 4 , bone morphogenetic protein 4, isoform 3 , Bone morphogenetic protein 4 , bone morphogenetic protein 4-like , bone morphogenetic protein 2 , etID309839.20 , swirl , swr , BMP-2B , BMP-4 , bone morphogenetic protein 2B

GENE ID SPECIES
30612 Danio rerio
397874 Xenopus laevis
452912 Pan troglodytes
549788 Xenopus (Silurana) tropicalis
100034048 Equus caballus
100049354 Oryzias latipes
100137596 Papio anubis
100194815 Salmo salar
100221891 Taeniopygia guttata
100398270 Callithrix jacchus
100286408 Salmo salar
100449444 Pongo abelii
30632 Danio rerio
652 Homo sapiens
399322 Xenopus laevis
12159 Mus musculus
25296 Rattus norvegicus
407216 Bos taurus
490695 Canis lupus familiaris
100860789 Capra hircus
100113425 Sus scrofa
396165 Gallus gallus
100009569 Oryctolagus cuniculus
100733516 Cavia porcellus
443502 Ovis aries
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