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BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Additionally we are shipping BRMS1 Proteins (11) and BRMS1 Kits (4) and many more products for this protein.
Showing 10 out of 65 products:
Human Monoclonal BRMS1 Primary Antibody for IP, ELISA - ABIN565191
Liu, Smith, Jones: Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. in Molecular and cellular biology 2006
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Human Monoclonal BRMS1 Primary Antibody for ELISA, WB - ABIN393891
Wu, McEwen, Harihar, Baker, DeWald, Zhou: BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study. in Cancer letters 2010
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Human Monoclonal BRMS1 Primary Antibody for WB - ABIN393598
Frolova, Edmonds, Bodenstine, Seitz, Johnson, Feng, Welch, Frost: A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers. in Tumour biology 2009
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Human Polyclonal BRMS1 Primary Antibody for WB - ABIN1881120
Vaidya, Sanchez, Kim, Welch: Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells. in Cancer letters 2009
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we identify a therapeutically exploitable posttranslational mechanism by which CK2alpha-mediated degradation of BRMS1 promotes metastases in lung cancer
our study characterized DAPK1 (show DAPK1 Antibodies) as a novel transcriptional target of BRMS1. Transcriptional activation of DAPK1 (show DAPK1 Antibodies) might be another important mechanism accounting for the metastasis suppressive activity of BRMS1.
BRMS1 promoter methylation and aberrant protein expression seem to be related to high-risk types of human papilloma virus-induced carcinogenesis in uterine cervix.
miR (show MLXIP Antibodies)-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1.
expression of BRMS1 and/or HPA (show HPSE Antibodies) might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma
A novel link has been discussed between CDK2 (show CDK2 Antibodies) expression and cell migration by characterizing the CDK2 (show CDK2 Antibodies)-mediated phosphorylation of BRMS1.
Phosphorylation of BRMS1 by CDK2 (show CDK2 Antibodies) regulates the migration of tumor cells.
Data show that Cullin3 exerts its function through promoting breast-cancer metastasis suppressor 1 (BRMS1) protein degradation, which was associated with epithelial-mesenchymal transition (EMT (show ITK Antibodies)), migration and invasion.
The studies reviewed here with respect to BRMS1 structure, cellular effects, intracellular signaling, and clinical value consolidate the importance of BRMS1 in the development of metastasis.
Aberrant methylation of BRMS1 frequently occurs in the down-regulation of BRMS1 in triple negative breast cancer and that it may play a role in the metastasis of breast cancer.
findings indicate the expression of Brms1L (show BRMS1L Antibodies) depends on beta-catenin (show CTNNB1 Antibodies) activity and contributes to follicle stimulating hormone beta (show FSHB Antibodies) induction by Gonadotropin-Releasing Hormone.
The Brms1 suppressed pulmonary metastasis and promoted apoptosis of tumor cells located in the lungs but not in the mammary glands.
BRMS1 may participate in transcriptional regulation via interaction with the mSin3.HDAC (show HDAC3 Antibodies) complex
results show for the first time that BRMS1 contains both nuclear import and export signals enabling its nucleo-cytoplasmic shuttling
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
breast cancer metastasis suppressor 1
, breast cancer metastasis-suppressor 1
, breast cancer metastasis-suppressor 1 homolog
, breast cancer metastasis-suppressor 1-like protein