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anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) Antibodies

BUB1B encodes a kinase involved in spindle checkpoint function. Additionally we are shipping Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) Proteins (6) and Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BUB1B 701 O60566
BUB1B 171576  
BUB1B 12236 Q9Z1S0
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Top anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) Antibodies at antibodies-online.com

Showing 10 out of 153 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/HepG2 cells, treated with ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of BUB1B (arrow) using rabbit polyclonal BUB1B A... Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Sheep Un-conjugated IHC (fro), WB 0.25 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF Immunofluorescence of monoclonal antibody to BUB1B on HeLa cell (antib... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of BUBR1 on a HeLa cell lysate (Human cervical e... Immunofluorescence staining of HeLa cells (Human cervical epitheloid c... 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated IHC (p), PLA, RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to BUB1B on formalin-fixed par... BUB1B monoclonal antibody (M02), clone 2G5 Western Blot analysis of BU... 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ICC, IF   100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 4 Days
$324.50
Details

BUB1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Rat (Rattus) , , ,
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Mouse (Murine) , , , ,
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Top referenced anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) Antibodies

  1. Human Polyclonal BUB1B Primary Antibody for WB - ABIN2801914 : Donadelli, Benatti, Remuzzi, Morigi, Gullans, Benigni, Remuzzi, Noris: Identification of a novel gene--SSK1--in human endothelial cells exposed to shear stress. in Biochemical and biophysical research communications 1998 (PubMed)
    Show all 5 references for ABIN2801914

  2. Human Polyclonal BUB1B Primary Antibody for EIA, IHC (p) - ABIN360515 : Chan, Schaar, Yen: Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. in The Journal of cell biology 1998 (PubMed)
    Show all 5 references for ABIN360515

  3. Human Monoclonal BUB1B Primary Antibody for IF - ABIN393631 : Suijkerbuijk, van Osch, Bos, Hanks, Rahman, Kops: Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy. in Cancer research 2010 (PubMed)
    Show all 5 references for ABIN393631

  4. Human Polyclonal BUB1B Primary Antibody for IHC (p), WB - ABIN392627 : Cahill, da Costa, Carson-Walter, Kinzler, Vogelstein, Lengauer: Characterization of MAD2B and other mitotic spindle checkpoint genes. in Genomics 1999 (PubMed)
    Show all 4 references for ABIN392627

  5. Human Monoclonal BUB1B Primary Antibody for IHC (p), PLA - ABIN560109 : Chambers: The molecular basis of pluripotency in mouse embryonic stem cells. in Cloning and stem cells 2005 (PubMed)
    Show all 4 references for ABIN560109

  6. Human Monoclonal BUB1B Primary Antibody for IF, WB - ABIN968853 : Chan, Jablonski, Sudakin, Hittle, Yen: Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. in The Journal of cell biology 1999 (PubMed)
    Show all 3 references for ABIN968853

  7. Human Polyclonal BUB1B Primary Antibody for ELISA, WB - ABIN1533524 : Cahill, Lengauer, Yu, Riggins, Willson, Markowitz, Kinzler, Vogelstein: Mutations of mitotic checkpoint genes in human cancers. in Nature 1998 (PubMed)

  8. Human Monoclonal BUB1B Primary Antibody for ICC, IF - ABIN2668286 : Liu, Rattner, Jablonski, Yen: Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. in The Journal of cell biology 2006 (PubMed)

  9. Mouse (Murine) Polyclonal BUB1B Primary Antibody for IHC (fro), WB - ABIN265006 : Davenport, Fernandes, Harris, Neale, Goorha: The mouse mitotic checkpoint gene bub1b, a novel bub1 family member, is expressed in a cell cycle-dependent manner. in Genomics 1999 (PubMed)

More Antibodies against Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) Interaction Partners

Xenopus laevis Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) interaction partners

  1. Together, our findings demonstrate that Bub1 (show BUB1 Antibodies) acts at multiple points to assure the correct kinetochore formation.

Fruit Fly (Drosophila melanogaster) Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) interaction partners

  1. The Bub3 (show BUB3 Antibodies)-BubR1 complex on broken DNA inhibits the APC (show APC Antibodies)/C locally via the sequestration of Cdc20 (show CDC20 Antibodies).

  2. a model in which Polo (show PLK1 Antibodies) controls Mps1-dependent BubR1 phosphorylation to promote Cdc20 (show CDC20 Antibodies) kinetochore recruitment and sustained SAC (show ADCY10 Antibodies) function.

  3. Data show that the Mad2 (show MAD2L1 Antibodies) kinetochore dimerization recruitment mechanism is conserved and that the recruitment of Cdc20 (show CDC20 Antibodies) to kinetochores in Drosophila requires BubR1 but not Mad2 (show MAD2L1 Antibodies).

  4. Reduced BubR1 or Polo (show PLK1 Antibodies) function results in abnormal segregation of acentric chromatids, a decrease in acentric chromosome tethering, and a great reduction in adult survival.

  5. BubR1's role in mitosis is discussed.

  6. BubR1 is required for normal synchrony and progression of syncytial nuclei through mitosis and to maintain the mitotic arrest of the polar body chromosomes after completion of meiosis

  7. BubR1 is required to promote stable microtubule kinetochore attachment. Activation of the mechanism that corrects inappropriate kinetochore attachment requires the antagonistic effects of BubR1 and CENP-E (show CENPE Antibodies).

  8. Recruitment of BubR1 by dysfunctional telomeres inhibits Cdc20 (show CDC20 Antibodies)-APC (show APC Antibodies) function, preventing the metaphase-to-anaphase transition.

Human Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) interaction partners

  1. We show that kinetochore recruitment of BUBR1 and BUB3 (show BUB3 Antibodies) by BUB1 (show BUB1 Antibodies) is dispensable for SAC (show ADCY10 Antibodies) activation

  2. Data suggest that both BubR1 and SNCG (show SNCG Antibodies) may be promising predictive marker rather than prognostic marker in patients with breast cancer.

  3. BubR1 knockdown significantly decreased cellular invasion but slightly affect cellular proliferation on both Ca9 (show CA9 Antibodies)-22 and Cal (show FBLIM1 Antibodies)-27 cells.

  4. BubR1 contributes to preventing premature aging. [review]

  5. Suggest human papillomavirus E2 protein (show UBE2B Antibodies) provokes BUBR1-dependent aneuploidy in HPV-induced cervical cancer.

  6. In conclusion, the results presented here suggest that Mad2 (show MAD2L1 Antibodies) and BubR1 could be used as prognostic markers of tumor progression and new pharmacological targets in the treatment for gastric cancer .

  7. Co-depletion of MAD2 (show MAD2L1 Antibodies) and BUBR1 causes cell cycle arrest and cell death in addition to aneuploidy.

  8. By sequestering PIDD (show PIDD Antibodies) at the kinetochore, BubR1 acts to delay PIDDosome formation until the next cycle, defining a new mechanism by which cells evade apoptosis during mitosis.

  9. a Cdc20 (show CDC20 Antibodies) binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

  10. study shows that SIRT2 (show SIRT2 Antibodies) is a deacetylase for BubR1 K250, although the abnormally prolonged SAC (show ADCY10 Antibodies) activation observed in SIRT2 (show SIRT2 Antibodies) knockdown cells is not accompanied by a change in BubR1 levels or by delayed progression from prometaphase to anaphase

Mouse (Murine) Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) interaction partners

  1. These data reveal that BubR1 plays a multifaceted role in chromosome segregation during the first meiotic division and suggest that age-related decline of BubR1 is a key determinant of the formation of aneuploid oocytes during aging.

  2. BubR1 (-/-) embryos were aneuploid and had an increased level of premature sister chromatid separation.

  3. Low BubR1 expression almost completely inhibited intimal hyperplasia after carotid ligation by suppressing the proliferation of VSMCs, which was caused, in part, by delayed cell cycle progression.

  4. the loss of BubR1 levels with age is due to a decline in NAD(+) and the ability of SIRT2 (show SIRT2 Antibodies) to maintain lysine-668 of BubR1 in a deacetylated state, which is counteracted by the acetyltransferase CBP (show CREBBP Antibodies).

  5. BubR1 insufficiency elicits an aging response that is counteracted by p53 (show TP53 Antibodies) and involves single or multiple p53 (show TP53 Antibodies) targets, depending on the tissue type.

  6. BubR1 acetylation is essential for embryonic development.

  7. these data demonstrate that the BUBR1 GTTA mutation compromises longevity and healthspan, raising the interesting possibility that mono-allelic changes in BUBR1 might contribute to differences in aging rates in the general population.

  8. Hhigh-level expression of BubR1 extends lifespan and delays age-related deterioration and aneuploidy in several tissues.

  9. BubR1 is a spindle assembly checkpoint protein regulating meiotic progression of oocytes.

  10. BUBR1 is essential for early embryonic development and normal hematopoiesis

Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) Antigen Profile

Protein Summary

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Gene names and symbols associated with BUB1B

  • BUB1 mitotic checkpoint serine/threonine kinase B (bub1b) antibody
  • budding uninhibited by benzimidazoles 1 homolog beta (yeast) (BUB1B) antibody
  • Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (bub1b) antibody
  • Bub1 homologue (Bub1) antibody
  • Bub1-related kinase (BubR1) antibody
  • BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) antibody
  • BUB1 mitotic checkpoint serine/threonine kinase B (Bub1b) antibody
  • budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) (Bub1b) antibody
  • 31/13 antibody
  • AU045529 antibody
  • BcDNA:LD23835 antibody
  • Bub1 antibody
  • BUB1-like antibody
  • Bub1A antibody
  • bub1b antibody
  • BUB1beta antibody
  • bubr1 antibody
  • BubRI antibody
  • CG7838 antibody
  • CG 7838 antibody
  • CG14030 antibody
  • CG14030/Bub1 antibody
  • dBUB1 antibody
  • Dmbub1 antibody
  • Dmel\\CG7838 antibody
  • Dmel\\CG14030 antibody
  • hBUBR1 antibody
  • l(2)k03113 antibody
  • l(2)k06109 antibody
  • MAD3L antibody
  • mcl(2)Z1525 antibody
  • MVA1 antibody
  • SSK1 antibody

Protein level used designations for BUB1B

BUB1 budding uninhibited by benzimidazoles 1 homolog beta , budding uninhibited by benzimidazoles 1 beta , budding uninhibited by benzimidazoles 1 homolog beta , mitotic checkpoint serine/threonine-protein kinase BUB1 beta , budding uninhibited by benzimidazoles 1 homolog beta (yeast) , mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like , Bub1-PA , CG14030-PA , Bub1 , BubR1-PA , CG7838-PA , bub related one , mcl(2)Z1525 , MAD3/BUB1-related protein kinase , mitotic checkpoint kinase MAD3L , budding uninhibited by benzimidazoles 1 homolog, beta

GENE ID SPECIES
378923 Xenopus laevis
453324 Pan troglodytes
537027 Bos taurus
100125106 Xenopus (Silurana) tropicalis
100196482 Salmo salar
100413586 Callithrix jacchus
100423079 Macaca mulatta
100455824 Pongo abelii
100464546 Ailuropoda melanoleuca
100607252 Nomascus leucogenys
100629735 Equus caballus
33758 Drosophila melanogaster
35522 Drosophila melanogaster
378922 Gallus gallus
701 Homo sapiens
171576 Rattus norvegicus
608350 Canis lupus familiaris
12236 Mus musculus
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