BUB1B Products
(Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
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This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008].
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Featured BUB1B Categories
BUB1B Antibodies
High quality antibodies with extensive validation data.
BUB1B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BUB1B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA, RNAi
Validations
- (5)
- (7)
Cat. No.
ABIN560109
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IF, FACS
Validations
- (6)
Cat. No.
ABIN1496997
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN1497002
Quantity
100 μL
Datasheet
Datasheet
Recommended BUB1B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569511
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346985
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346987
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BUB1B products
: "PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly." in: Molecular cancer research : MCR, Vol. 16, Issue 1, pp. 3-15, (2019) (PubMed).: "Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma." in: Endocrinology, Vol. 159, Issue 7, pp. 2532-2544, (2019) (PubMed).
: "Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1336-44, (2016) (PubMed).
: "Prognostic implications of securin expression and sub-cellular localization in human breast cancer." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 319-31, (2016) (PubMed).
: "Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis." in: Oncogene, Vol. 32, Issue 24, pp. 2973-83, (2013) (PubMed).
: "Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis." in: Molecular biology of the cell, Vol. 23, Issue 23, pp. 4526-42, (2012) (PubMed).
: "The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores." in: Journal of cell science, Vol. 125, Issue Pt 13, pp. 3243-53, (2012) (PubMed).
: "Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit." in: Molecular and cellular biology, Vol. 31, Issue 7, pp. 1478-91, (2011) (PubMed).
: "Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13052-9, (2011) (PubMed).
: "Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01." in: Molecular cancer therapeutics, Vol. 10, Issue 5, pp. 784-94, (2011) (PubMed).
Synonyms and alternative names related to BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), BUB1B, mitotic checkpoint serine/threonine kinase (Bub1b), BUB1 mitotic checkpoint serine/threonine kinase B (Bub1b), BUB1B, mitotic checkpoint serine/threonine kinase L homeolog (bub1b.L), BUB1B, mitotic checkpoint serine/threonine kinase (bub1b), Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (bub1b), Bub1 kinase (Bub1), AU045529, BUB1, bub1, BUB1-like, Bub1A, bub1b, BUB1beta, BUBR1, BubR1, BubRI, CG14030, CG14030/Bub1, Dmel\\CG14030, hBUBR1, MAD3L, MVA1, SSK1Protein level used designations for BUB1B
- MAD3/BUB1-related protein kinase
- budding uninhibited by benzimidazoles 1 homolog beta
- mitotic checkpoint kinase MAD3L
- mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- budding uninhibited by benzimidazoles 1 beta
- budding uninhibited by benzimidazoles 1 homolog, beta
- BUB1 budding uninhibited by benzimidazoles 1 homolog beta
- budding uninhibited by benzimidazoles 1 homolog beta (yeast)
- mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like
- Bub1-PA
- CG14030-PA
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