You are viewing an incomplete version of our website. Please click to reload the website as full version.

C-Type Lectin Domain Family 4, Member G Proteins (CLEC4G)

CLEC4G encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Additionally we are shipping CLEC4G Kits (9) and CLEC4G Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CLEC4G CLEC4G 689004  
CLEC4G 339390 Q6UXB4
CLEC4G 75863 Q8BNX1
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CLEC4G Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Cells Human Fc Tag 50 μg Log in to see 21 to 31 Days
$319.00
Details
HOST_HEK-293 Human Fc Tag   0.05 mg Log in to see 2 to 3 Days
$584.38
Details

CLEC4G Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for C-Type Lectin Domain Family 4, Member G (CLEC4G) Interaction Partners

Pig (Porcine) C-Type Lectin Domain Family 4, Member G (CLEC4G) interaction partners

  1. In this study, there was experimentally identified the cDNA and the gene encoding porcine CLEC4G.

Human C-Type Lectin Domain Family 4, Member G (CLEC4G) interaction partners

  1. Japanese encephalitis virus infected cells through three virus receptors: DC-SIGN (show CD209 Proteins), DC-SIGNR (show CLEC4M Proteins) and LSECtin.

  2. The results indicate that LSECtin plays an important role in colorectal carcinoma liver metastasis and may be a promising new target for intervention in metastasis formation.

  3. The mobility of LSECtin-carbohydrate recognition domain increased after addition of Ca(2 (show CA2 Proteins)+) and N-acetylglucosamine.

  4. Axl (show AXL Proteins),Tyro3 (show TYRO3 Proteins),DC-SIGN (show CD209 Proteins) and LSECtin are identified as new virus receptors for Lassa virus cell entry.

  5. The human LSECtin have been shown to bind Ebola virus glycoprotein with equivalent affinities, and the GlcNAcbeta1-2Man disaccharide has been demonstrated to be an effective inhibitor of this interaction.

  6. The interaction between CD44 (show CD44 Proteins) & LSECtin is dependent on protein-glycan recognition. CD44 (show CD44 Proteins) is the 1st identified endogenous ligand of LSECtin, & similarly, LSECtin is a novel ligand of CD44 (show CD44 Proteins).

  7. results indicate that LSECtin is a novel member of a family of proteins comprising CD23, DC-SIGN, and DC-SIGNR and might function in vivo as a lectin receptor

  8. LSECtin is a pathogen-associated molecular pattern receptor in human myeloid cells; results suggest that LSECtin participates in antigen uptake and internalization

  9. Our results reveal important differences between Ebola virus and HIV-1 capture by DC-SIGN (show CD209 Proteins)/R and LSECtin and hint towards different biological functions of these lectins.

  10. LSECtin is expressed by liver myeloid cells, and its expression is dependent on the PU.1 transcription factor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member G (CLEC4G) interaction partners

  1. Data show that C-type lectin-like domain family 4, member g (Clec4g) suppresses beta-Site amyloid precursor protein cleaving enzyme-1 (BACE1 (show BACE Proteins))-mediated amyloid-beta (Abeta (show APP Proteins)) peptides generation.

  2. When expressed in B16 melanoma cells, LSECtin promoted tumor growth, whereas its blockade slowed tumor growth in either wild-type or LSECtin-deficient mice.

  3. LSECtin-mediated signaling up-regulates the threshold of CD4(+) T cell activation via tuning the expression of Cbl-b.

  4. LSECtin may facilitate the reduction of liver inflammation at the cost of delaying virus clearance, an effect that might be hijacked by the virus as an escape mechanism.

  5. The studies provide a basis for using mouse LSECtin, and knockout mice lacking this receptor, to model the biological properties of the human receptor.

  6. Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response.

CLEC4G Protein Profile

Protein Summary

This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CLEC4G

  • C-type lectin domain family 4, member G (CLEC4G)
  • C-type lectin domain family 4, member G (Clec4g)
  • C-type lectin domain family 4, member g (Clec4g)
  • 4930572L20Rik protein
  • DTTR431 protein
  • LP2698 protein
  • LSECtin protein
  • RGD1562320 protein
  • UNQ431 protein

Protein level used designations for CLEC4G

C-type lectin domain family 4, member G , C-type lectin superfamily 4, member G , C-type lectin domain family 4 member G , DC-SIGN related C-type lectin , LSECtin , liver and lymph node sinusoidal endothelial cell C-type lectin

GENE ID SPECIES
484999 Canis lupus familiaris
507332 Bos taurus
689004 Rattus norvegicus
742238 Pan troglodytes
100240718 Sus scrofa
339390 Homo sapiens
75863 Mus musculus
Selected quality suppliers for CLEC4G Proteins (CLEC4G)
Did you look for something else?