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C-Type Lectin Domain Family 5, Member A (CLEC5A) ELISA Kits

CLEC5A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC5A Antibodies (40) and CLEC5A Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CLEC5A 23601 Q9NY25
CLEC5A 23845 Q9R007
CLEC5A 679787  
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Top CLEC5A ELISA Kits at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 7 pg/ml 28-1800 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 3.9 pg/ml 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
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Monkey
96 Tests Log in to see 16 to 21 Days
$999.43
Details
Rat
96 Tests Log in to see 16 to 21 Days
$999.43
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Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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Sheep
96 Tests Log in to see 16 to 21 Days
$999.43
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Guinea Pig
96 Tests Log in to see 16 to 21 Days
$999.43
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Dog
96 Tests Log in to see 16 to 21 Days
$999.43
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Rabbit
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for CLEC5A Interaction Partners

Human C-Type Lectin Domain Family 5, Member A (CLEC5A) interaction partners

  1. Concordant overexpression of MDL-1 and DAP12 (show TYROBP ELISA Kits) were correlated with increased production of proinflammatory cytokines in rheumatoid arthritis patients.

  2. Blockade of CLEC5A inhibits NLRP3 (show NLRP3 ELISA Kits) inflammasome activation and pyrotopsis in dengue-virus-infected inflammatory macrophages. Thus, DV can activate NLRP3 (show NLRP3 ELISA Kits) inflammasome via CLEC5A.

  3. No significant associations were noted between the genotypes and allele frequency of the 4 CLEC5A tSNPs between controls and Kawasaki disease patients.

  4. CLEC5A is homodimeric at the cell surface and binds to dengue virus serotypes 1-4.

  5. CLEC5A expression in monocyte/macrophage and granulocytes is regulated by PU.1.

  6. The crystal volume per unit weight (VM) was calculated to be 2.34 A3 Da-1 (show TPM2 ELISA Kits), with nine molecules per asymmetric unit and a solvent content of 47.38%. CLEC5A plays an important role in the pathophysiology of dengue-virus-induced disease.

  7. blockade of CLEC5A-mediated signalling attenuates the production of proinflammatory cytokines by macrophages infected with Dengue virus (either alone or complexed with an enhancing antibody)

Mouse (Murine) C-Type Lectin Domain Family 5, Member A (CLEC5A) interaction partners

  1. cigarette smoke-induced macrophage responsiveness is mediated by CLEC5A, and CLEC5A is required for the development of inflammation, proinflammatory cytokine expression, and airspace enlargement.

  2. Japanese encephalitis virus (JEV) directly interacts with CLEC5A and induces DAP12 (show TYROBP ELISA Kits) phosphorylation in macrophages.

  3. triggering of MDL-1 on immature myeloid cells and production of NO and TNF-alpha (show TNF ELISA Kits) may play a critical role in the pathogenesis of shock

  4. This is the first report that shows the involvement of monocyte and macrophage receptor CLEC5A in severe inflammatory response in Japanese encephalitis virus (JEV) infection of brain.

  5. Activation of MDL-1 leads to enhanced recruitment of inflammatory macrophages and neutrophils to the joint and promotes bone erosion.

  6. MDL-1 plays an important role in immune defense as a result of an innate immunity, which involves neutrophils and macrophages

  7. MDL-1 associates with both DAP12 (show TYROBP ELISA Kits) and DAP10 (show HCST ELISA Kits) in osteoclasts and bone marrow-derived macrophages, where DAP10 (show HCST ELISA Kits) association depends almost entirely on DAP12 (show TYROBP ELISA Kits), suggesting a formation of MDL-1-DAP12 (show TYROBP ELISA Kits)/DAP10 (show HCST ELISA Kits) trimolecular complexes.

CLEC5A Antigen Profile

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.

Gene names and symbols associated with CLEC5A

  • C-type lectin domain family 5, member A (CLEC5A) antibody
  • C-type lectin domain family 5, member a (Clec5a) antibody
  • C-type lectin domain family 5, member A (Clec5a) antibody
  • Clecsf5 antibody
  • Ly100 antibody
  • MDL-1 antibody
  • Mdl1 antibody

Protein level used designations for CLEC5A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 , C-type lectin domain family 5 member A , C-type lectin superfamily member 5 , myeloid DAP12-associating lectin 1 , myeloid DAP12-associating lectin-1 , MDL-1 , myeloid DAP12-associating lectin long form , type II transmembrane protein MDL-1

GENE ID SPECIES
23601 Homo sapiens
397050 Sus scrofa
615201 Bos taurus
23845 Mus musculus
679787 Rattus norvegicus
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