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anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) Antibodies

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. Additionally we are shipping CTCFL Proteins (5) and CTCFL Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTCFL 296420  
CTCFL 140690 Q8NI51
CTCFL 664799 A2APF3
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Top anti-CTCFL Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CTCFL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-CTCFL  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  CTCFL is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chimpanzee Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-BORIS antibody shows detection of a predominant band corresponding to BORIS in human tissue lysates (arrowhead).   Lane 1 contains lysate from human prostate tissue.  Lane 2 contains lysate from human spleen tissue.  A predominant band at ~75 kDa is observed.  Molecular weight estimation was made by comparison to prestained MW markers as indicated. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ChIPSeq, ChIP, WB Boris / CTCFL antibody (pAb) tested by ChIP-Seq. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 ug of chromatin from human testis and 2 µl of antibody. ChIP DNA was sequenced on the Illumina HiSeq and 20 million sequence tags were mapped to identify Boris / CTCFL binding sites. The image shows binding across a region of chromosome 7. You can view the complete data set in the UCSC Genome Browser, starting at this specific location, here. BORIS / CTCFL antibody (pAb) tested by Western blot. Whole cell extract (10 μg per lane) from HEK293T cells transfected with either vector alone (lanes 1 and 3), with a FLAG-tagged human BORIS expression vector (lanes 2 and 4) or mouse testis nuclear extract (30 μg, lane 5) was probed with either BORIS / CTCFL antibody at 1:2,000 (lanes 1 and 2) or 1:500 (lane 5) or anti-FLAG tag (lanes 3 and 4). 100 μL Log in to see 1 to 2 Days
$478.33
Details
Mouse Rat Un-conjugated ICC, WB   100 μg Log in to see 8 to 10 Days
$522.50
Details
Rat Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

CTCFL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CTCFL Antibodies

  1. Chimpanzee Polyclonal CTCFL Primary Antibody for EIA, WB - ABIN401325 : Loukinov, Pugacheva, Vatolin, Pack, Moon, Chernukhin, Mannan, Larsson, Kanduri, Vostrov, Cui, Niemitz, Rasko, Docquier, Kistler, Breen, Zhuang, Quitschke, Renkawitz, Klenova, Feinberg, Ohlsson, Morse, Lobanenkov: BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN401325

  2. Human Polyclonal CTCFL Primary Antibody for ELISA, WB - ABIN129668 : Dougherty, Ichim, Liu, Reznik, Min, Ghochikyan, Agadjanyan, Reznik: Selective apoptosis of breast cancer cells by siRNA targeting of BORIS. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN129668

  3. Human Polyclonal CTCFL Primary Antibody for WB - ABIN2775056 : Hong, Kang, Abdullaev, Flanagan, Pack, Fischette, Adnani, Loukinov, Vatolin, Risinger, Custer, Chen, Zhao, Nguyen, Barrett, Lobanenkov, Schrump: Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. in Cancer research 2005 (PubMed)

More Antibodies against CTCFL Interaction Partners

Human CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) interaction partners

  1. BORIS is associated with cancer stem cell-enriched populations of several epithelial tumor cells and the different phenotypes depend on the origin of tumor cells.

  2. Data found that BORIS and CTCF (show CTCF Antibodies) expression in low-grade squamous intraepithelial lesions and invasive cervical carcinoma is higher than in normal samples. The possible utility of BORIS and CTCF (show CTCF Antibodies) as biomarkers in cervical neoplasm requires further analysis.

  3. In the first detailed analysis in cancer, a marked loss of CHD8 (show CHD8 Antibodies) expression and increased BORIS/CTCF (show CTCF Antibodies) ratio indicate frequent disruption of CTCF (show CTCF Antibodies) and its effector genes in PCa (show FLVCR1 Antibodies).

  4. Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.

  5. High BORIS transcript variants are associated with laryngeal squamous cell carcinomas.

  6. CTCFL/BORIS was amongst the top ranked genes differentially expressed between endometrioid and non-endometrioid tumors, and increasing mRNA level of CTCFL/BORIS was highly significantly associated with poor survival.

  7. The serum levels of MAGE (show MAGEB10 Antibodies)-A and BORIS mRNA, as well as let-7b were significantly higher in patients.

  8. results provide novel insights into the determinants of NOTCH3 (show NOTCH3 Antibodies) overexpression in cancer cells, by revealing a key role for BORIS as the main mediator of transcriptional deregulation of NOTCH3 (show NOTCH3 Antibodies)

  9. BORIS is an RNA-binding protein that associates with polysomes.

  10. Neither the MTHFR (show MTHFR Antibodies) polymorphism, nor CTCFL mutations explain a pattern of sperm hypomethylation at paternally imprinting loci

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) interaction partners

  1. The TGFB (show TGFB1 Antibodies) pathway as most affected by embryonic Ctcfl expression.

  2. down-regulation of endogenous BORIS by specific shRNAs inhibited both RNA transcription and cell cycle progression. The results altogether suggest a role for BORIS in coordinating S phase events with mitosis.

  3. Rb2 (show RBL2 Antibodies) coimmunolocalizes with the chromatin insulator CCCTC-binding factor (CTCF (show CTCF Antibodies)) and BORIS in T-antigen-positive but not in T-antigen-negative cells.

  4. These findings show that BORIS expression is more widespread than previously believed, and suggest a role for BORIS in nucleolar function.

  5. findings indicate that BORIS-induced expression of TSP50 (show PRSS50 Antibodies) is governed by accessibility and binding of BORIS to the promoter

  6. These findings define transcriptional regulation of CST (Gal3st1 (show GAL3ST1 Antibodies)) expression as a critical role for BORIS in spermatogenesis.

  7. CTCFL and PRMT7 (show PRMT7 Antibodies) may play a role in male germline imprinted gene methylation.

  8. CTCFL/BORIS is a methylation-independent DNA-binding protein (show HSF4 Antibodies) that preferentially binds to the paternal H19 (show NCKAP1 Antibodies) differentially methylated region

  9. DNA damage-induced and ATR (show ATR Antibodies)/Rfx1 (show RFX1 Antibodies)-mediated increase of miR (show MLXIP Antibodies)-709 expression in exposed testes may be a protective mechanism that effectively decreases a cellular level of BORIS to prevent massive aberrant erasure of DNA methylation (show HELLS Antibodies) after radiation exposure.

CTCFL Antigen Profile

Protein Summary

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCFL

  • CCCTC-binding factor (zinc finger protein)-like (Ctcfl) antibody
  • CCCTC-binding factor (zinc finger protein)-like (CTCFL) antibody
  • CCCTC-binding factor (zinc finger protein)-like (LOC100360757) antibody
  • Boris antibody
  • CT27 antibody
  • CTCF-T antibody
  • CTCFL antibody
  • dJ579F20.2 antibody
  • HMGB1L1 antibody
  • OTTMUSG00000016680 antibody

Protein level used designations for CTCFL

CCCTC-binding factor (zinc finger protein)-like , CCCTC-binding factor-like protein , brother of the regulator of imprinted sites , brother of regulator of imprinted sites , transcriptional repressor CTCFL , transcriptional repressor CTCFL-like , BORIS-like protein , CTCF paralog , CTCF-like protein , HMG-1L1 , cancer/testis antigen 27 , putative high mobility group protein 1-like 1 , putative high mobility group protein B1-like 1 , zinc finger protein CTCF-T , BORIS , Brother of the regulator of imprinted sites , likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL)

GENE ID SPECIES
296420 Rattus norvegicus
458360 Pan troglodytes
477271 Canis lupus familiaris
100079649 Ornithorhynchus anatinus
100144618 Bos taurus
100360757 Rattus norvegicus
100475700 Ailuropoda melanoleuca
701500 Macaca mulatta
100126237 Sus scrofa
100140647 Bos taurus
100435120 Pongo abelii
100583303 Nomascus leucogenys
100618914 Monodelphis domestica
140690 Homo sapiens
664799 Mus musculus
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