You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antibodies

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. Additionally we are shipping CD244 Molecule, Natural Killer Cell Receptor 2B4 Proteins (23) and CD244 Molecule, Natural Killer Cell Receptor 2B4 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD244 51744 Q9BZW8
CD244 64025 Q9JLM2
CD244 18106 Q07763
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 Antibodies at antibodies-online.com

Showing 10 out of 137 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, IP, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SLAMF4 in Daudi cell lysate with SLAMF4 antib... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated FACS, IP Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN C... 0.5 mg Log in to see 6 to 8 Days
$632.50
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IP, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CD244 antibody, IHC(P) IHC(P): Human Tonsil Tissue Anti- CD244 antibody, Western blotting All lanes: Anti CD244  at 0.5ug... 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse FITC FACS 100 Tests Log in to see 10 to 12 Days
$211.97
Details
Human Mouse APC FACS 100 Tests Log in to see 10 to 12 Days
$288.07
Details

CD244 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Rat (Rattus) , , , ,

Mouse (Murine) , , , ,
, ,

Top referenced anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 Antibodies

  1. Human Monoclonal CD244 Primary Antibody for FACS - ABIN2661609 : Boles, Stepp, Bennett, Kumar, Mathew: 2B4 (CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes. in Immunological reviews 2001 (PubMed)
    Show all 9 references for ABIN2661609

  2. Human Monoclonal CD244 Primary Antibody for FACS - ABIN2658548 : Messmer, Eissmann, Stark, Watzl: CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 8 references for ABIN2658548

  3. Human Polyclonal CD244 Primary Antibody for EIA, WB - ABIN783458 : Claus, Meinke, Bhat, Watzl: Regulation of NK cell activity by 2B4, NTB-A and CRACC. in Frontiers in bioscience : a journal and virtual library 2007 (PubMed)
    Show all 2 references for ABIN783458

  4. Human Polyclonal CD244 Primary Antibody for ELISA - ABIN1995503 : Mathew, Rao, Kim, Bambard, Mathew: Functional role of human NK cell receptor 2B4 (CD244) isoforms. in European journal of immunology 2009 (PubMed)

  5. Human Monoclonal CD244 Primary Antibody for FACS - ABIN120314 : Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  6. Human Polyclonal CD244 Primary Antibody for EIA, IP - ABIN487961 : Tangye, Lazetic, Woollatt, Sutherland, Lanier, Phillips: Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)

More Antibodies against CD244 Molecule, Natural Killer Cell Receptor 2B4 Interaction Partners

Human CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. SLAMF4 gene and surface protein expression was down-regulated in CD8 (show CD8A Antibodies)+ T cells from SLE patients compared with that in cells obtained from healthy donors. SLAMF4+ effector memory cells produced more granzyme B (show Gzmb Antibodies) and perforin (show PRF1 Antibodies) than SLAMF4- cells.

  2. GSK-3 (show GSK3b Antibodies) undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D (show KLRK1 Antibodies) and 2B4, either individually or in combination.

  3. Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8 (show CD8A Antibodies)+ T Cell Hyporesponsiveness to Alloantigen

  4. CD8 (show CD8A Antibodies)(+) T cells require 2B4 for Epstein-Barr virus-specific immune control, because 2B4 blockade after CD8 (show CD8A Antibodies)(+) T-cell depletion did not further aggravate symptoms of the infection.

  5. CD244 expression/signaling in tuberculosis correlates with high levels of a long noncoding RNA (lncRNA)-BC050410 [named as lncRNA-AS-GSTT1(1 (show GSTT1 Antibodies)-72) or lncRNA-CD244] in the CD244(+)CD8 (show CD8A Antibodies)(+) T-cell subpopulation.

  6. show that in addition to NKG2D (show KLRK1 Antibodies), human CEACAM1 (show CEACAM1 Antibodies) can inhibit NK-cell activation via NKp30 (show NCR3 Antibodies) or 2B4

  7. this study investigates the structural requirements for the recruitment of the human-activating NK-cell receptors NKG2D (show KLRK1 Antibodies) and 2B4 to detergent-resistant membrane fractions in the murine BA/F3 cell line and in the human NK-cell line NKL (show GLIS2 Antibodies).

  8. Study of SAP (show APCS Antibodies) expression is specific but may have insufficient sensitivity for screening XLP1 as a single tool; however, combination with 2B4 functional assay allows identification of all cases

  9. Blockade of 2B4/CD48 (show CD48 Antibodies) interaction resulted in improvement in function via perforin (show PRF1 Antibodies) expression and degranulation as measured by CD107a (show LAMP1 Antibodies) surface mobilization on HTLV-1 specific CD8 (show CD8A Antibodies)+ T cells.

  10. In patients suffering from X-linked lymphoproliferative disease (XLP1), SAP (show APCS Antibodies) is nonfunctional, not only abolishing the activating function of 2B4, but rendering this receptor inhibitory.

Mouse (Murine) CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. 2B4 dampens T-independent B cell responses.

  2. DCs from CD244(-/-) mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno-modulatory receptors found on DCs.

  3. Data show that enforced expression of inhibitor of differentiation protein Id3 (show ID3 Antibodies) specifically increased the persistence of Cd244 protein 2B4(+) virus-specific CD8 (show CD8A Antibodies)(+) T cells.

  4. Molecular dynamic simulation explains unbinding and unfolding of CD48 (show CD48 Antibodies)-2B4 protein complexes.

  5. Signaling via SLAMF4 controls expansion of cytotoxic CD8alphabeta(+) IELs, which regulate the reversible depletion of lamina propria phagocytes and inflammation in the small intestine.

  6. CD244 (2B4) has a regulatory effect on mast cells and eosinophils in murine allergic inflammation.

  7. NKG2D (show KLRK1 Antibodies) ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

  8. blockade of CD28 (show CD28 Antibodies) signals in the presence of preserved CTLA-4 (show CTLA4 Antibodies) signals results in the unique up-regulation of 2B4 on primary CD8 (show CD8A Antibodies)(+) effectors, and that this 2B4 expression plays a critical functional role in controlling antigen-specific T8 cell responses

  9. In the absence of SAP (show APCS Antibodies), signaling through the SLAM (show SLAMF1 Antibodies) family members Ly108 (show SLAMF6 Antibodies) and 2B4 resulted in increased recruitment of the SHP-1 (show PTPN6 Antibodies) phosphatase, associated with altered SHP-1 (show PTPN6 Antibodies) localization and decreased activation of Src (show SRC Antibodies) kinases at the synapse.

  10. Ox-LDL significantly promoted the interaction of natural killer cells and dendritic cells via CD48 (show CD48 Antibodies)-2B4 contact-dependent mechanisms.

CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antigen Profile

Protein Summary

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD244

  • CD244 molecule, natural killer cell receptor 2B4 (CD244) antibody
  • Cd244 molecule, natural killer cell receptor 2B4 (Cd244) antibody
  • CD244 natural killer cell receptor 2B4 (Cd244) antibody
  • 2B4 antibody
  • C9.1 antibody
  • CD244 antibody
  • F730046O15Rik antibody
  • Ly90 antibody
  • NAIL antibody
  • NKR2B4 antibody
  • Nmrk antibody
  • SLAMF4 antibody

Protein level used designations for CD244

CD244 molecule, natural killer cell receptor 2B4 , natural killer cell receptor 2B4 , NK cell activation inducing ligand NAIL , NK cell activation-inducing ligand , NK cell type I receptor protein 2B4 , SLAM family member 4 , h2B4 , signaling lymphocytic activation molecule 4 , CD244 natural killer cell receptor 2B4 , NKR2B4 , non MHC restricted killing associated , non-MHC restricted killing associated , transmembrane NK cell receptor 2B4 , NK cell receptor 2B4

GENE ID SPECIES
488644 Canis lupus familiaris
513468 Bos taurus
100594419 Nomascus leucogenys
51744 Homo sapiens
64025 Rattus norvegicus
18106 Mus musculus
Selected quality suppliers for anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antibodies
Did you look for something else?