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anti-CD276 Molecule (CD276) Antibodies

The protein encoded by CD276 belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Additionally we are shipping CD276 Proteins (31) and CD276 Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD276 102657 Q8VE98
CD276 80381 Q5ZPR3
CD276 315716 Q7TPB4
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Top anti-CD276 Antibodies at antibodies-online.com

Showing 10 out of 205 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Fluorescein FACS Detection of B7-H3 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human B7-H3 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Mouse PE FACS 100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated FACS, WB Detection of B7-H3 in Human Dendritic Cells by Flow Cytometry. Human monocyte-derived dendritic cells were stained with Mouse Anti-Human B7-H3 Monoclonal Antibody. Detection of Human B7-H3 by Western Blot. Western blot shows lysates of LNCaP human prostate cancer cell line and U2OS human osteosarcoma cell line. PVDF membrane was probed with 2 ug/mL of Mouse Anti-Human B7-H3 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$294.00
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of PC-3 cells using CD276 mouse mAb (green) and negative control (purple) . Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues (left) and ovarian cancer tissues (right) using CD276 mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated ELISA, IP, WB 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Goat Un-conjugated FACS, IHC, SimWes, WB Detection of B7-H3 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate carcinoma cells were stained with Goat Anti-Human B7-H3 Antigen Affinity-purified Polyclonal Antibody. B7-H3 in Human Melanoma. B7-H3 was detected in immersion fixed paraffin-embedded sections of human melanoma using Goat Anti-Human B7-H3 Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. 100 μg Log in to see 8 to 9 Days
$388.50
Details
Human Rat PE FACS 25 μg Log in to see 10 to 12 Days
$130.45
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-B7-H3/CD276 (SP206) antibody in 293 (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 2 to 3 Days
$374.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CD276 Antibody [NBP1-88966] - Staining of human prostate shows membranous positivity in glandular cells. Immunocytochemistry/Immunofluorescence: CD276 Antibody [NBP1-88966] - Staining of human cell line A-431 shows positivity in vesicles. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details

CD276 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD276 Antibodies

  1. Human Monoclonal CD276 Primary Antibody for FACS - ABIN2663289 : Ford, McVicar: TREM and TREM-like receptors in inflammation and disease. in Current opinion in immunology 2009 (PubMed)
    Show all 8 references for ABIN2663289

  2. Human Polyclonal CD276 Primary Antibody for FACS, IHC - ABIN4900125 : Jang, Park, Choi, Kim, Hwang, Baek, Suh, Mun, Suh: 12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells. in International journal of oncology 2007 (PubMed)
    Show all 7 references for ABIN4900125

  3. Human Monoclonal CD276 Primary Antibody for FACS, WB - ABIN4900123 : Sucker, Zhao, Real, Heeke, Bielefeld, Maβen, Horn, Moll, Maltaner, Horn, Schilling, Sabbatino, Lennerz, Kloor, Ferrone, Schadendorf, Falk, Griewank, Paschen: Genetic evolution of T-cell resistance in the course of melanoma progression. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 5 references for ABIN4900123

  4. Human Monoclonal CD276 Primary Antibody for FACS - ABIN317048 : Sun, Vale, Leung, Kanwar, Gupta, Krissansen: Mouse B7-H3 induces antitumor immunity. in Gene therapy 2003 (PubMed)
    Show all 3 references for ABIN317048

  5. Human Monoclonal CD276 Primary Antibody for FACS - ABIN317045 : Chapoval, Ni, Lau, Wilcox, Flies, Liu, Dong, Sica, Zhu, Tamada, Chen: B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. in Nature immunology 2001 (PubMed)
    Show all 3 references for ABIN317045

  6. Human Monoclonal CD276 Primary Antibody for FACS, IHC - ABIN969018 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 2 references for ABIN969018

  7. Human Polyclonal CD276 Primary Antibody for ICC, IF - ABIN4282792 : Lemke, Pfenning, Sahm, Klein, Kempf, Warnken, Schnölzer, Tudoran, Weller, Platten, Wick: Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)

  8. Human Monoclonal CD276 Primary Antibody for FACS - ABIN4897213 : Niehage, Steenblock, Pursche, Bornhäuser, Corbeil, Hoflack: The cell surface proteome of human mesenchymal stromal cells. in PLoS ONE 2011 (PubMed)

  9. Human Polyclonal CD276 Primary Antibody for ELISA, IP - ABIN1998403 : Loos, Hedderich, Friess, Kleeff: B7-h3 and its role in antitumor immunity. in Clinical & developmental immunology 2010 (PubMed)

More Antibodies against CD276 Interaction Partners

Cow (Bovine) CD276 Molecule (CD276) interaction partners

  1. Anterior pituitary gland progenitor cells containing 4Ig-B7-H3 (CD276) may play a critical role in the immunoendocrine network.

Mouse (Murine) CD276 Molecule (CD276) interaction partners

  1. CD276 is broadly expressed by tumor cells and tumor vasculature but Is dispensable for tumor growth.

  2. this study shows that B7-H3 participates in the development of acute pancreatitis

  3. Data show that B7-H3 protein is over-expressed in cerulein-induced acute pancreatitis, and anti-B7-H3 monoclonal antibody can attenuate the inflammation and alleviate the injury of pancreas and lung tissues.

  4. Ablation of B7-H3 but Not B7-H4 (show VTCN1 Antibodies) Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  5. Murine B7-H3 is a positive co-stimulatory molecule in the regulation of T cell-mediated immune responses.

  6. B7-H3 inhibits T cell proliferation. FG loop of the IgV domain plays a critical role in this function. B7-H3 crystallized as an unusual dimer arising from the exchange of the G strands in the IgV domains of partner molecules

  7. The study investigates the role of B7-H3 in pancreatic cancer progression and shows that this protein promotes cancer cell migration and invasiveness in vitro and in vivo.

  8. Graft prolongation achieved by CTLA4 (show CTLA4 Antibodies) Ig was shortened both by B7-H3 blockade and the absence of recipient B7-H3.

  9. Macrophage-tumor cell interaction-induced membrane-bound B7-H3 represents a novel immune escape mechanism which links the pro-inflammatory response to immune tolerance in the tumor milieu.

  10. Exogenous administration of B7-H3 strongly amplifies the inflammatory response, exacerbates blood-brain barrier disruption, and aggravates the clinical disease status in Streptococcus pneumoniae-infected C3H/HeN (show RPS6 Antibodies) wild-type mice.

Human CD276 Molecule (CD276) interaction partners

  1. CD276 is broadly expressed by tumor cells and tumor vasculature but Is dispensable for tumor growth.

  2. B7-H3 hijacks SREBP-1 (show SREBF1 Antibodies)/FASN (show FASN Antibodies) signaling mediating abnormal lipid metabolism in lung cancer

  3. BRCC3 may play a role in B7-H3-induced 5-Fu resistance.

  4. We found that B7-H3 promoted the Warburg effect, evidenced by increased glucose uptake and lactate production in B7-H3-expressing cells. B7-H3 also increased the protein levels of HIF1alpha (show HIF1A Antibodies) and its downstream targets, LDHA (show LDHA Antibodies) and PDK1 (show PDK1 Antibodies), key enzymes in the glycolytic pathway

  5. B7-H3 and B7-H4 (show VTCN1 Antibodies) are involved in esophageal squamous cell carcinoma (ESCC) progression and development and their coexpression could be valuable prognostic indicators.

  6. Upregulated sB7-H3 expression in MPEs is correlated with TNM (show ODZ1 Antibodies) stage of NSCLC and may serve as a potential biomarker for NSCLC-derived MPEs

  7. High expression of B7-H3 is associated with Colorectal cancer.

  8. Elevated B7-H3 expression is significantly associated with poor survival in cancer patients. (Meta-analysis)

  9. The results provide novel insights into the function of B7-H3 in cancer, and suggest that targeting of B7-H3 may be a novel alternative to improve current anticancer therapies.

  10. Suggesting that B7-H3 and Tregs may act cooperatively in tumor immune evasion, leading to poor outcomes for NSCLC patients.

CD276 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-CD276 Molecule (CD276) Antibodies

  • CD276 molecule (CD276) antibody
  • CD276 molecule (cd276) antibody
  • CD276 antigen (Cd276) antibody
  • Cd276 molecule (Cd276) antibody
  • 4Ig-B7-H3 antibody
  • 6030411F23Rik antibody
  • AU016588 antibody
  • B7-H3 antibody
  • B7H3 antibody
  • B7RP-2 antibody
  • sc:d0645 antibody
  • zgc:158279 antibody

Protein level used designations for anti-CD276 Molecule (CD276) Antibodies

CD276 molecule , CD276 antigen-like , CD276 antigen homolog , CD276 antigen , B7 homolog 3 , B7-H3 , costimulatory molecule

GENE ID SPECIES
100471106 Ailuropoda melanoleuca
447379 Xenopus laevis
467818 Pan troglodytes
487638 Canis lupus familiaris
508656 Bos taurus
699877 Macaca mulatta
791140 Danio rerio
100195762 Salmo salar
100397167 Callithrix jacchus
100446767 Pongo abelii
102657 Mus musculus
415315 Gallus gallus
80381 Homo sapiens
315716 Rattus norvegicus
Selected quality suppliers for anti-CD276 (CD276) Antibodies
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