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CDGSH Iron Sulfur Domain 2 Proteins (CISD2)

The protein encoded by CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. Additionally we are shipping CISD2 Kits (27) and CISD2 Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CISD2 493856 Q8N5K1
CISD2 67006 Q9CQB5
Rat CISD2 CISD2 295457  
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Top CISD2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Lithobates catesbeiana His tag   1 mg Log in to see 56 to 66 Days
$2,097.33
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,097.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CISD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for CDGSH Iron Sulfur Domain 2 (CISD2) Interaction Partners

Human CDGSH Iron Sulfur Domain 2 (CISD2) interaction partners

  1. NAF-1 (show TNIP1 Proteins) is a major player in the metabolic regulation of breast cancer cells.

  2. A novel CISD2 mutation is associated with wolfram syndrome 2.

  3. Studied the expression pattern and clinicopathological significance of CISD2 in patients with early-stage cervical cancer.

  4. Data show that the protein levels of NAF-1 (CISD2) and mNT (show MNT Proteins) (CISD1 (show CISD1 Proteins)) are elevated in human epithelial breast cancer cells.

  5. CISD2 has a role in lifespan control and disease [review]

  6. A single missense mutation was identified in a novel, highly conserved zinc-finger gene, ZCD2, in three consanguineous families of Jordanian descent with Wolfram syndrome (WFS).

  7. The authors show that Miner1 is a homodimer harboring two redox-active 2Fe-2S clusters, indicating for the first time an association of a redox-active FeS (show FES Proteins) protein with Wolfram Syndrome 2.

Mouse (Murine) CDGSH Iron Sulfur Domain 2 (CISD2) interaction partners

  1. Cisd2 deficiency impairs the activation of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling

  2. These results suggest that the ABIN1 (show TNIP1 Proteins)-mediated hyperactivation of IKKs and MAPKs might mediate chronic inflammation and CVD development.

  3. Results suggest that that Cisd2 plays an important role in intracellular Ca21 homeostasis, which is required for the differentiation and functioning of adipocytes as well as the regulation of glucose homeostasis in mice.

  4. Miner1 is a redox protein that resides in the ER and that regulates the UPR and mitochondrial function.

  5. studies link ABIN-1 (show TNIP1 Proteins) with IL-23 (show IL23A Proteins) and IL-17 (show IL17A Proteins), and they provide cellular and molecular mechanisms by which ABIN-1 (show TNIP1 Proteins) regulates susceptibility to psoriasis.

  6. data reveal ABIN1 (show TNIP1 Proteins) as an essential anti-inflammatory component of TLR-signaling pathways that controls C/EBPbeta (show CEBPB Proteins) activity

  7. ABIN1 (show TNIP1 Proteins) requires its ubiquitin binding domain and cooperates with TAX1BP1 (show TAX1BP1 Proteins) and A20 (show TNFAIP3 Proteins) to restrict antiviral signaling.

  8. the interaction of ABIN1 (show TNIP1 Proteins) with polyubiquitin (show UBB Proteins) is required to limit the activation of TLR-MyD88 (show MYD88 Proteins) pathways and prevent autoimmunity

  9. CISD2 has a role in lifespan control and disease [review]

  10. Using a murine model of allergen-induced asthma, we have demonstrated that adenovirus-mediated delivery of ABIN-1 (show TNIP1 Proteins) to the lung epithelium results in a reduction of allergen-induced eosinophil infiltration into the lungs.

CISD2 Protein Profile

Protein Summary

The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.

Gene names and symbols associated with CISD2

  • CDGSH iron sulfur domain 2 (cisd2-a)
  • CDGSH iron sulfur domain 2 (CISD2)
  • CDGSH iron sulfur domain 2 (cisd2)
  • CDGSH iron sulfur domain 2 (cisd2-b)
  • CDGSH iron sulfur domain 2 (Cisd2)
  • nuclear assembly factor 1 ribonucleoprotein (Naf1)
  • TNFAIP3 interacting protein 1 (Tnip1)
  • 1500009M05Rik protein
  • 1500026J14Rik protein
  • 1500031D15Rik protein
  • ABIN protein
  • ABIN-1 protein
  • ABIN1 protein
  • AI848398 protein
  • AU018810 protein
  • B630006A20Rik protein
  • cisd2 protein
  • ERIS protein
  • Miner1 protein
  • NAF-1 protein
  • Naf1 protein
  • Nef protein
  • Noxp70 protein
  • RGD1306802 protein
  • RGD1566242 protein
  • VAN protein
  • WFS2 protein
  • Zcd2 protein
  • zgc:64148 protein

Protein level used designations for CISD2

CDGSH iron-sulfur domain-containing protein 2A , CDGSH iron sulfur domain-containing protein 2A , CDGSH iron sulfur domain-containing protein 2-A , zinc finger, CDGSH-type domain 2 , CDGSH iron-sulfur domain-containing protein 2 , CDGSH iron sulfur domain-containing protein 2 , CDGSH iron sulfur domain-containing protein 2-B , CDGSH iron sulfur domain-containing protein 2B , CDGSH iron-sulfur domain-containing protein 2B , endoplasmic reticulum intermembrane small protein , mitoNEET related 1 , mitoNEET-related 1 protein , nutrient-deprivation autophagy factor-1 , CDGSH iron sulfur domain 2 , miner1 , nervous system over-expressed protein 70 , nervous system overexpressed protein 70 , H/ACA ribonucleoprotein complex non-core subunit NAF1 , nuclear assembly factor 1 homolog , A20-binding inhibitor of NF-kappa B activation , Nef-associated factor 1 , TNFAIP3-interacting protein 1 , virion-associated nuclear shuttling protein

GENE ID SPECIES
398808 Xenopus laevis
422714 Gallus gallus
496970 Xenopus (Silurana) tropicalis
393354 Danio rerio
447022 Xenopus laevis
493856 Homo sapiens
610084 Canis lupus familiaris
781260 Bos taurus
67006 Mus musculus
295457 Rattus norvegicus
100716445 Cavia porcellus
101106939 Ovis aries
306387 Rattus norvegicus
57783 Mus musculus
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