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CDK5 Regulatory Subunit Associated Protein 1-Like 1 Proteins (CDKAL1)

The protein encoded by CDKAL1 is a member of the methylthiotransferase family. Additionally we are shipping CDKAL1 Antibodies (39) and CDKAL1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDKAL1 54901 Q5VV42
CDKAL1 68916 Q91WE6
Rat CDKAL1 CDKAL1 361243  
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Top CDKAL1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CDKAL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) Interaction Partners

Human CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) interaction partners

  1. our data suggested that CDKAL1 gene variants have a significant effect on the response to anti-TNF (show TNF Proteins) therapies among Psoriasis patients

  2. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (show ADCY5 Proteins), ADRA2A (show ADRA2A Proteins), CDKAL1, CDKN2A/B, GRB10 (show GRB10 Proteins), and TCF7L2 (show TCF7L2 Proteins)

  3. rs10946398 associated with markers of impaired insulin (show INS Proteins) secretion

  4. We observed novel selection signals in CDKAL1 and NEGR1 (show NEGR1 Proteins), well-known diabetes and obesity susceptibility genes

  5. study found SNP rs7754840 in CDKAL1, rs864745 in JAZF1 (show JAZF1 Proteins), and rs35767 in IGF1 (show IGF1 Proteins) might serve as potential susceptibility loci for type 2 diabetes in the Uyghur population

  6. The rs7754840 and rs7756992 SNPs of the CDKAL1 gene were found to be associated with Gestational Diabetes Mellitus in this south Indian population.

  7. study identified the association between type 2 diabetes risk variants in CDKAL1 and birthweight in Chinese Han individuals, and the carrier of risk allele within SRR (show SRR Proteins) had the trend of reduced birthweight.

  8. Provide evidence against a role for dysregulated expression of CDKAL1-v1 in mediating the association between intronic SNPs in CDKAL1 and susceptibility to type 2 diabetes.

  9. The results support a central role of CDKAL1 and TCF7L2 (show TCF7L2 Proteins) in T2DM susceptibility in Southwest Asian populations and provide a plausible component for understanding molecular mechanisms involved in the disease.

  10. CDKAL1 gene rs7756992 A/G polymorphism was significantly associated with T2DM. The person with G allele of CDKAL1 gene rs7756992 A/G polymorphism might be predisposed to T2DM.

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) interaction partners

  1. CDKAL1 may affect such compensatory mechanisms regulating glucose homeostasis through interaction with diet

  2. Knockout mice with pancreatic beta-cell-specific lack of cdkal1 show pancreatic islet hypertrophy and impaired blood glucose control.

  3. Data show that Cdkal1 is a mammalian methylthiotransferase that biosynthesizes 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) in tRNA(Lys (show LYZ Proteins))(UUU) and that it is required for the accurate translation of AAA (show AAAS Proteins) and AAG (show C16orf35 Proteins) codons.

  4. CDKAL1 controls first-phase insulin (show INS Proteins) exocytosis in beta cells by facilitating ATP generation, K(ATP) channel responsiveness and the subsequent activity of Ca(2 (show CA2 Proteins)+) channels through pathways other than CDK5 (show CDK5 Proteins)-mediated regulation

CDKAL1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes.

Gene names and symbols associated with CDKAL1

  • CDK5 regulatory subunit associated protein 1-like 1 (CDKAL1)
  • CDK5 regulatory subunit associated protein 1-like 1 (cdkal1)
  • CDK5 regulatory subunit associated protein 1-like 1 (Cdkal1)
  • 1190005B03Rik protein
  • 6620401C13Rik protein
  • MGC76088 protein
  • MGC78779 protein
  • zgc:65864 protein

Protein level used designations for CDKAL1

CDK5 regulatory subunit-associated protein 1-like 1 , tRNA-t(6)A37 methylthiotransferase , threonylcarbamoyladenosine tRNA methylthiotransferase , CDK5 regulatory subunit associated protein 1-like 1

GENE ID SPECIES
100052309 Equus caballus
393600 Danio rerio
394802 Xenopus (Silurana) tropicalis
420823 Gallus gallus
432014 Xenopus laevis
530159 Bos taurus
587594 Strongylocentrotus purpuratus
747778 Pan troglodytes
100024680 Monodelphis domestica
54901 Homo sapiens
488240 Canis lupus familiaris
68916 Mus musculus
361243 Rattus norvegicus
100512355 Sus scrofa
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