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CMTM7 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. Additionally we are shipping CMTM7 Antibodies (35) and CMTM7 Proteins (4) and many more products for this protein.
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Findings indicate the role of CMTM7 protein in the regulation of epidermal growth factor receptor (EGFR (show EGFR ELISA Kits))-AKT (show AKT1 ELISA Kits) proto-oncogene (show RAB1A ELISA Kits) protein signaling in tumor cells, and as a molecule related to Rab5 (show RAB5A ELISA Kits) GTP-binding protein activation.
Loss of CMTM7 by promoter CpG methylation is associated with neoplasms.
The CMTM7 expression may be related to survival of patients with non-smallcell lung cancer and a unique prognostic factor. CMTM7 may play an important role in NSCLC development.
CMTM7 functions to link sIgM and BLNK (show BLNK ELISA Kits) in the plasma membrane.
Bioinformatics based on CKLF2 (show CKLF ELISA Kits) cDNA and protein sequences in combination with experimental validation identified CKLFSF1 (show CMTM1 ELISA Kits)-8 gene clusters, between the SCY (show CELSR1 ELISA Kits) and the TM4SF (show TSPAN1 ELISA Kits) gene families. The 8 family members were cloned and characterized.
The reduction of B-1a cells in Cmtm7(flox/) mice was associated with reduced BCR (show BCR ELISA Kits) expression.
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified.
CKLF-like MARVEL transmembrane domain-containing protein 7
, chemokine-like factor superfamily 7
, chemokine-like factor super family 7
, chemokine-like factor super family member 7 variant 2
, chemokine-like factor superfamily member 7