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Enhances cisplatin-mediated apoptosis, when overexpressed. Additionally we are shipping CLPTM1L Antibodies (51) and many more products for this protein.
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research seems to provide strong evidence for an association between CLPTM1L rs402710C/T and TERT rs2736100A/C SNPs and the risk of OSSC, and suggests that higher tumor RTL values and positive hTERT expression may be applicable as early prognostic markers
Homozygous carriers of the CLPTM1L minor C allele presented with faster 6 years telomeres shortening rate compared to carriers of the major allele.
Variant in CLPTM1L gene is associated with lung cancer susceptibility.
CLPTM1L and TERT (show TERT Proteins) have been implicated in cancers, and CIITA (show CIITA Proteins) is considered as the "master control factor" for the expression of NPC (show NPC1 Proteins)-associated MHC class II (show HLA-DPA1 Proteins) genes. These suggested that both SNPs might be functional. Altogether, our findings expand our understanding of the genetic contribution to nasopharyngeal carcinoma (NPC (show NPC1 Proteins)), risk and provide novel biological insights into NPC (show NPC1 Proteins) pathogenesis.
A case-control study examined the potential association of 4 CLPTM1L SNPs (rs4975616, rs402710, rs401681, and rs31489) with lung cancer in a Chinese Han population. Minor alleles of all four were significantly associated with decreased lung cancer risk.
The data demonstrate that CLPTM1L overexpression can predict poor prognosis in patients with lung cancer and suggest that CLPTM1L might be associated with the regulation of cell migration and invasion.
Data suggest that single nucleotide polymorphisms (SNPs) in the telomerase (TERT (show TERT Proteins))-cleft lip and palate transmembrane protein 1-like protein (CLPTM1L) locus may play a role in mediating the susceptibility to nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) in Chinese.
CLPTM1L Polymorphism is associated with Nasopharyngeal Carcinoma.
This meta-analysis suggests that T allele of CLPTM1L-telomerase reverse transcriptase (show TERT Proteins) rs401681 polymorphism is associated with an increased PC risk, especially among Chinese.
rs2736100 on TERT-CLPTM1L indicates a poor prognosis for lung cancer in the Chinese Han population.
Enhances cisplatin-mediated apoptosis, when overexpressed.
, cleft lip and palate transmembrane protein 1-like protein-like
, CLPTM1-like protein
, cisplatin resistance related protein CRR9p
, cisplatin resistance-related protein 9
, cleft lip and palate transmembrane protein 1-like protein