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CUGBP, Elav-Like Family Member 4 Proteins (CELF4)

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Additionally we are shipping CELF4 Kits (38) and CELF4 Antibodies (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CELF4 56853 Q9BZC1
CELF4 108013 Q7TSY6
Rat CELF4 CELF4 307540  
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Top CELF4 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,336.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,375.17
Details

CELF4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for CUGBP, Elav-Like Family Member 4 (CELF4) Interaction Partners

Human CUGBP, Elav-Like Family Member 4 (CELF4) interaction partners

  1. Authors report a modifying effect of a polymorphism of CELF4 on the dose-dependent association between anthracyclines and cardiomyopathy, which possibly occurs through a pathway that involves the expression of abnormally spliced TNNT2 (show TNNT2 Proteins) variants.

  2. Determination of CELF4 protein domains required for RNA splicing.

Mouse (Murine) CUGBP, Elav-Like Family Member 4 (CELF4) interaction partners

  1. Celf4 might be regulating alternative early in retinal development.

  2. we suggest that CELF4 deficiency leads to abnormal neuronal function by combining a specific effect on neuronal excitation with a general impairment of synaptic transmission.

  3. Data point strongly to the conclusion that Celf4 deletion primarily from excitatory neurons promotes convulsive seizure phenotypes.

  4. CELF (show CEBPD Proteins) protein activity is required for normal alternative splicing in the heart in vivo and normal CELF (show CEBPD Proteins)-mediated alternative splicing regulation is in turn required for normal cardiac function.

  5. Brunol4 deficiency in mice results in a complex seizure phenotype, likely due to the coordinate dysregulation of several molecules, providing a unique new animal model of epilepsy

CELF4 Protein Profile

Protein Summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CELF4

  • CUGBP, Elav-like family member 4 (celf4)
  • CUGBP, Elav-like family member 4 (CELF4)
  • CUGBP, Elav-like family member 4 (Celf4)
  • A230070D14Rik protein
  • Brul4 protein
  • BRUNOL-4 protein
  • Brunol4 protein
  • C130060B05Rik protein
  • zgc:92761 protein

Protein level used designations for CELF4

CELF-4 , CUG-BP- and ETR-3-like factor 4 , CUGBP Elav-like family member 4 , RNA-binding protein BRUNOL-4 , bruno-like protein 4 , RNA binding protein Bruno-like 4 , Bruno -like 4, RNA binding protein , CUG-BP and ETR-3 like factor 4 , LYST-interacting protein LIP9 , RNA-binding protein BRUNOL4 , bruno-like 4, RNA binding protein , CUG-BP and ETR-3-like factor 4

GENE ID SPECIES
436835 Danio rerio
100190784 Xenopus laevis
56853 Homo sapiens
535177 Bos taurus
108013 Mus musculus
307540 Rattus norvegicus
100174655 Pongo abelii
100732038 Cavia porcellus
100521138 Sus scrofa
101114837 Ovis aries
426889 Gallus gallus
610838 Canis lupus familiaris
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