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Calcium Channel, Voltage-Dependent, beta 2 Subunit Proteins (CACNB2)

CACNB2 encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. Additionally we are shipping Calcium Channel, Voltage-Dependent, beta 2 Subunit Antibodies (134) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CACNB2 783 Q08289
CACNB2 12296 Q8CC27
CACNB2 116600 Q8VGC3
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Top Calcium Channel, Voltage-Dependent, beta 2 Subunit Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,899.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

CACNB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) Interaction Partners

Human Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) interaction partners

  1. Five serious mental disorders and three major cardiovascular diseases have recently been linked to the CACNB2 gene coding for the Cavbeta2 subunits

  2. ADM (show ADM Proteins) genotype AA was associated with the highest values of systolic and diastolic blood pressure (BP), while CACNB2 genotype CC carriers had the highest values of diastolic BP in childhood.

  3. In the gene-based analysis, CACNB2 and CTCF (show CTCF Proteins) showed the strongest evidence for association with schizophrenia in both the present samples and in those of the Psychiatric Genetics Consortium datasets.

  4. Chronic atrial fibrillation increases miR (show MLXIP Proteins)-21 expression in human atrial myocytes and decreases I(Ca,L) density by downregulating CACNA1C (show CACNA1C Proteins)/CACNB2 expression.

  5. Three rare missense mutations of CACNB2 (G167S, S197F, and F240L) found in Autism Spectrum Disorders (ASD (show ARSD Proteins))-affected families, are reported.

  6. High prevalence of CACNA2D1 (show CACNA2D1 Proteins), SCN5A (show SCN5A Proteins), and CACNB2 genetic variants in the Danish population previously associated with Brugada syndrome has been found in new exome data.

  7. Association of the SNP rs2932538 in MOV10 and SNP rs4373814 in CACNB2 with an increased risk of hypertension in a Chinese Han population.

  8. Genetic variations in CYP17A1, CACNB2 and PLEKHA7 were related to blood pressure traits and/or hypertension in Chinese She population.

  9. Genetic testing reveals disease-causing mutations in depolarizing sodium (SCN5A (show SCN5A Proteins)) or calcium (CaCNB2b) channels in 5 infants with rapid ventricular tachycardia, conduction abnormalities, and Brugada-like syndrome.

  10. This study provided that cacnb2 are associated with Bipolar I in the Han Chinese population.

Mouse (Murine) Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) interaction partners

  1. Membrane Interaction of the beta2e Subunit of Voltage-Gated Ca(2 (show CA2 Proteins)+) Channels

  2. Dynamic phospholipid interaction of beta2e subunit regulates the gating of voltage-gated Ca2 (show CA2 Proteins)+ channels.

  3. a model in which CaVbeta promotes anterograde trafficking of the L-type channels by anchoring them to actin filaments in their itinerary to the plasma membrane.

  4. We conclude that phosphorylation of the C-terminal sites in Ca(v)beta(2), Ser (show SIGLEC1 Proteins)(1928), Ser (show SIGLEC1 Proteins)(1512), and Ser (show SIGLEC1 Proteins)(1570) of the Ca(v)1.2 (show CACNA1C Proteins) protein is functionally not involved in the adrenergic regulation of the murine cardiac Ca(v)1.2 (show CACNA1C Proteins) channel.

  5. phosphorylation event is one mechanism underlying ahnak1 (show AHNAK Proteins)'s modulator function on Cav1.2 (show CACNA1C Proteins) channel activity.

  6. Mice with cardiac-specific sequestration of the beta-subunit (show POLG Proteins) of the L-type calcium channel

  7. preferential binding between Cacna1c (show CACNA1C Proteins) and Cacnb2 in the heart

  8. Ca(V)beta(2) has an essential role in regulating the abundance and properties of Ca(V)1.3 (show CACNA1D Proteins) channels in IHCs and, thereby, is critical for IHC development and synaptic encoding of sound.

  9. expression of various CaVbeta2 proteins may be used to adapt the properties of LTCCs to changing myocardial requirements during development

Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) Protein Profile

Protein Summary

This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described.

Gene names and symbols associated with CACNB2

  • calcium channel, voltage-dependent, beta 2 subunit (CACNB2)
  • calcium channel, voltage-dependent, beta 2 subunit (Cacnb2)
  • AW060387 protein
  • CAB2 protein
  • CACNB2 protein
  • Cacnlb2 protein
  • CAVB2 protein
  • Cavbeta2 protein
  • Cchb2 protein
  • MYSB protein

Protein level used designations for CACNB2

calcium channel, voltage-dependent, beta 2 subunit , L-type calcium channel beta subunit , voltage-dependent L-type calcium channel subunit beta-2 , voltage-dependent L-type calcium channel subunit beta-2-like , CAB2 , calcium channel voltage-dependent subunit beta 2 , lambert-Eaton myasthenic syndrome antigen B , myasthenic (Lambert-Eaton) syndrome antigen B , cardiac calcium channel beta subunit , cardiac calcium channel beta-subunit

GENE ID SPECIES
100055971 Equus caballus
100192393 Cavia porcellus
100232478 Taeniopygia guttata
100172479 Pongo abelii
701226 Macaca mulatta
740138 Pan troglodytes
100020184 Monodelphis domestica
100410704 Callithrix jacchus
100524101 Sus scrofa
100580212 Nomascus leucogenys
783 Homo sapiens
327667 Bos taurus
100009277 Oryctolagus cuniculus
12296 Mus musculus
116600 Rattus norvegicus
428420 Gallus gallus
487113 Canis lupus familiaris
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