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anti-Calpain 3 (CAPN3) Antibodies

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. Additionally we are shipping Calpain 3 Kits (18) and Calpain 3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CAPN3 12335 Q64691
CAPN3 29155 P16259
CAPN3 825 P20807
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Top anti-Calpain 3 Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CAPN3 Antibody (C-term) flow cytometric analysis of HL-60 cells (right... CAPN3 Antibody (C-term) IHC analysis in formalin fixed and paraffin em... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CAPN3 Antibody (C-term) (ABIN653774) in HL-60... CAPN3 Antibody (C-term) (ABIN653774) IHC analysis in formalin fixed an... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE Cal... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Calpain 3 expression in MCF7 (A), PC12 (B) wh... 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$302.50
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 5 to 7 Days
$302.50
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC   50 μL Log in to see 8 to 10 Days
$390.50
Details

CAPN3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , ,

Rat (Rattus) , ,

Human , , , ,
,

Top referenced anti-Calpain 3 Antibodies

  1. Human Polyclonal Calpain 3 Primary Antibody for IHC - ABIN965743 : Richard, Broux, Allamand, Fougerousse, Chiannilkulchai, Bourg, Brenguier, Devaud, Pasturaud, Roudaut: Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. in Cell 1995 (PubMed)
    Show all 8 references for ABIN965743

  2. Human Polyclonal Calpain 3 Primary Antibody for FACS, IHC (p) - ABIN951007 : Charlton, Henderson, Richards, Hudson, Straub, Bushby, Barresi: Immunohistochemical analysis of calpain 3: advantages and limitations in diagnosing LGMD2A. in Neuromuscular disorders : NMD 2009 (PubMed)
    Show all 4 references for ABIN951007

More Antibodies against Calpain 3 Interaction Partners

Xenopus laevis Calpain 3 (CAPN3) interaction partners

  1. our results suggest that calcium influx through mechanosensitive TRPC1 channels on filopodia activates calpain to control growth cone turning during development.

Mouse (Murine) Calpain 3 (CAPN3) interaction partners

  1. Cleavage of C-terminal titin (show TTN Antibodies) by CAPN3 is associated with limb-girdle muscular dystrophy 2A and tibial muscular dystrophy.

  2. these studies reveal a novel interaction between CAPN3 and CaM (show Calm2 Antibodies) and identify CaM (show Calm2 Antibodies) as the first positive regulator of CAPN3 activity.

  3. data suggest that skNAC controls myoblast migration and sarcomere architecture in a calpain-dependent manner

  4. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1 (show FRG1 Antibodies), reducing Rbfox1 (show A2BP1 Antibodies) levels and leading to aberrant expression of an altered Calpain 3 protein through dysregulated splicing

  5. The Ky gene was downregulated in CAPN3 knockout muscles suggesting that Ky protease may play a complementary role in regulating muscle cytoskeleton homeostasis in response to changes in muscle activity

  6. The decrease in CaMKII (show CAMK2G Antibodies) signaling in the absence of CAPN3 is associated with a reduction of muscle adaptation response.

  7. stretch-induced dynamic redistribution of p94 is dependent on its protease activity and essential to protect muscle from degeneration

  8. roles for Na(+) dependence of p94

  9. In vitro experiments have then revealed that only PDLIM1 (show PDLIM1 Antibodies) is cleaved directly by calpain-3.

  10. analyzed both the sequences of appearance and the expression profiles of calpains 1, 2, 3 and calpastatin (show CAST Antibodies) during the course of myoblast differentiation

Pig (Porcine) Calpain 3 (CAPN3) interaction partners

  1. The higher CAPN3 gene expression in less tender muscles confirmed the lack of a direct involvement of calpain 3 in meat tenderization.

Human Calpain 3 (CAPN3) interaction partners

  1. We identified four novel CAPN3 mutations and demonstrated clinical and pathological heterogeneity in Korean patients with calpainopathy.

  2. Cleavage of C-terminal titin (show TTN Antibodies) by CAPN3 is associated with limb-girdle muscular dystrophy 2A and tibial muscular dystrophy.

  3. Calpain-3 over-expression induces p53 (show TP53 Antibodies) activation and redox imbalance in melanoma A375 cells.

  4. Phosphorylated CAPN3 is involved in the pathology of limb-girdle muscular dystrophy type 2A through defects in myofibril integrity and/or signaling pathways.

  5. results provide evidence that WT CAPN3 can be formed by the iMOC of two different complementary CAPN3 mutants

  6. In LGMD2A muscles the activation of the atrophy programme appeared to depend mainly upon induction of the ubiquitin-proteasome system

  7. a heterozygous deletion of the entire CAPN3 gene was found in a patients with Limb-girdle muscular dystrophy type 2A

  8. The results indicate that PDGF-C (show PDGFC Antibodies) upregulation and calpain-3 downregulation are involved in the aggressiveness of malignant melanoma and suggest that modulators of these proteins

  9. Suppression of transgenic CAPN3 expression in cardiac tissue prevents cardiac toxicity in a model of limb-girdle muscular dystrophy.

  10. Authors found that PLEIAD also interacts with CTBP1 (C-terminal binding protein 1 (show CTBP1 Antibodies)), a transcriptional co-regulator, and CTBP1 (show CTBP1 Antibodies) is proteolyzed in COS7 cells expressing CAPN3.

Cow (Bovine) Calpain 3 (CAPN3) interaction partners

  1. 2 CAPN3 transcripts in the skeletal muscle individuals of local black cattle from Jilin, China, were identified.

  2. Calpain-system gene markers have beneficial effects on eating quality, consistent with previous findings for objective meat quality.

  3. activated Capn3 may be involved in molecular pathways leading to the overexpression of E2F3, which in turn could be responsible for urothelial tumor cell proliferation

  4. A QTL for meat tenderness is located in the Calpain 3 region of bovine chromosome 10.

Calpain 3 (CAPN3) Antigen Profile

Protein Summary

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Gene names and symbols associated with anti-Calpain 3 (CAPN3) Antibodies

  • calpain 3, (p94) (capn3) antibody
  • calpain 3a, (p94) (capn3a) antibody
  • calpain 3 (CAPN3) antibody
  • calpain 3, (p94) (CAPN3) antibody
  • calpain 3 (Capn3) antibody
  • AI323605 antibody
  • CANP3 antibody
  • CANPL3 antibody
  • Capa-3 antibody
  • Capa3 antibody
  • CAPN3 antibody
  • LGMD2 antibody
  • LGMD2A antibody
  • Lp82 antibody
  • Lp84 antibody
  • Lp85 antibody
  • MGC80925 antibody
  • nCL-1 antibody
  • nCL1 antibody
  • p94 antibody
  • SKM-CALP antibody
  • SKM-CALPOV antibody
  • zgc:92687 antibody

Protein level used designations for anti-Calpain 3 (CAPN3) Antibodies

calpain 3 , calpain 3, (p94) , calpain-3 , lens-specific calpain Lp82 , CANP 3 , calcium-activated neutral proteinase 3 , calpain L3 , calpain p94 , muscle-specific calcium-activated neutral protease 3 , skeletal muscle specific calpain p94 , nCL-1 , new calpain 1 , skeletal muscle specific calpain , calpain p94, large [catalytic] subunit , calpain, large polypeptide L3 , muscle-specific calcium-activated neutral protease 3 large subunit , skeletal muscle-specific calpain , p94

GENE ID SPECIES
446888 Xenopus laevis
447832 Danio rerio
707913 Macaca mulatta
100008726 Oryctolagus cuniculus
12335 Mus musculus
29155 Rattus norvegicus
397349 Sus scrofa
825 Homo sapiens
281663 Bos taurus
423233 Gallus gallus
443038 Ovis aries
Selected quality suppliers for anti-Calpain 3 (CAPN3) Antibodies
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