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Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). Additionally we are shipping CNPY2 Antibodies (44) and CNPY2 Kits (1) and many more products for this protein.
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Human CNPY2 Protein expressed in Escherichia coli (E. coli) - ABIN1047580
Yokoyama-Kobayashi, Yamaguchi, Sekine, Kato: Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank. in Gene 1999
Show all 3 references for 1047580
Human CNPY2 Protein expressed in Human Cells - ABIN2005900
Danielsen, Sylvestersen, Bekker-Jensen, Szklarczyk, Poulsen, Horn, Jensen, Mailand, Nielsen: Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. in Molecular & cellular proteomics : MCP 2011
CNPY2 may play a critical role in colorectal cancer development by enhancing cell proliferation, migration, and angiogenesis and by inhibiting apoptosis through negative regulation of the p53 (show TP53 Proteins) pathway
The data demonstrate CNPY2 is widely distributed in tissues and suggest the protein has biological functions that have yet to be identified.
CNPY2 is a HIF-1alpha (show HIF1A Proteins)-regulated, secreted angiogenic growth factor that promotes smooth muscle cell migration, proliferation, and tissue revascularization.
These findings suggested that CNPY2 promoted cancer cell growth in renal cell carcinoma (show MOK Proteins) cells through regulating TP53 (show TP53 Proteins) gene expression.
Our results are consistent with an important role of FGF21 (show FGF21 Proteins) and Cnpy2/Msap in the regulation of LDLRs in cultured cells.
MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain in fetal and adult brain.
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity).
MIR-interacting saposin-like protein
, protein canopy homolog 2
, putative secreted protein ZSIG9
, transmembrane protein 4
, canopy 2 homolog
, putative secreted protein Zsig9