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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins (CEACAM1)

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Additionally we are shipping Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Antibodies (229) and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CEACAM1 26365 P31809
CEACAM1 634 P13688
CEACAM1 81613 P16573
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Top Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human CEACAM-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$280.50
Details

CEACAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, ,
Human , , , , , , , ,
, , ,
Rat (Rattus) , ,

Top referenced Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins

  1. Mouse (Murine) CEACAM1 Protein expressed in Human Cells - ABIN2007980 : Zalzali, Naudin, Bastide, Quittau-Prévostel, Yaghi, Poulat, Jay, Blache: CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium. in Oncogene 2008 (PubMed)
    Show all 4 references for ABIN2007980

  2. Human CEACAM1 Protein expressed in Human Cells - ABIN2003445 : Manor, Neer: Effects of cycloheximide on virus RNA replication in an inducible line of polyoma-transformed rat cells. in Cell 1975 (PubMed)
    Show all 4 references for ABIN2003445

  3. Rat (Rattus) CEACAM1 Protein expressed in Human Cells - ABIN2009336 : Hinoda, Neumaier, Hefta, Drzeniek, Wagener, Shively, Hefta, Shively, Paxton: Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen. in Proceedings of the National Academy of Sciences of the United States of America 1988 (PubMed)
    Show all 4 references for ABIN2009336

  4. Human CEACAM1 Protein expressed in Human Cells - ABIN2003447 : Oliveira-Ferrer, Tilki, Ziegeler, Hauschild, Loges, Irmak, Kilic, Huland, Friedrich, Ergün: Dual role of carcinoembryonic antigen-related cell adhesion molecule 1 in angiogenesis and invasion of human urinary bladder cancer. in Cancer research 2004 (PubMed)
    Show all 4 references for ABIN2003447

  5. Human CEACAM1 Protein expressed in HEK-293 Cells - ABIN2180867 : Watt, Fawcett, Murdoch, Teixeira, Gschmeissner, Hajibagheri, Simmons: CD66 identifies the biliary glycoprotein (BGP) adhesion molecule: cloning, expression, and adhesion functions of the BGPc splice variant. in Blood 1994 (PubMed)
    Show all 3 references for ABIN2180867

More Proteins for Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Interaction Partners

Cow (Bovine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. our data show that human and bovine CEACAM1 can both inhibit NK-cell cytotoxicity although they differ in their intracellular signaling motifs

  2. Data from cultured aortic endothelial cells suggest that CEACAM1 is involved in regulation of vascular endothelial cell reactions to oxidative stress/lipid peroxidation and in regulation of nitric oxide production in large vessels such as aorta.

  3. This data represents the first report of a functional link between CEACAM1 and the VEGFR2 (show KDR Proteins)/Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins)-mediated vascular permeability pathway.

  4. CEACAM1 has two alleles and serves as a pathogen receptor in cattle.

Mouse (Murine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.

  2. The increase in total fat mass in Cc1(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin (show POMC Proteins) neurons in the arcuate nucleus is unclear, leptin (show LEP Proteins) resistance and elevated hypothalamic fatty-acid synthase (show FASN Proteins) activity could underlie altered energy balance in these mice.

  3. Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.

  4. hepatic CEACAM1 expression at fasting is mediated by Pparalpha (show PPARA Proteins)-dependent mechanisms.

  5. Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.

  6. CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses

  7. High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin (show REN Proteins)-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.

  8. Ceacam1L acts as a crucial factor in glioblastoma-initiating cell maintenance and tumorigenesis by activating c-Src (show SRC Proteins)/STAT3 (show STAT3 Proteins) signaling. Monomers of the cytoplasmic domain of Ceacam1L bound to c-Src (show SRC Proteins) and STAT3 (show STAT3 Proteins) and induced their phosphorylation.

  9. CEACAM1 levels in the liver were reduced in prenatally stressed diet-induced obesity offspring after the high fat diet challenge, suggesting that preexisting genetic predisposition combined with prenatal stress increases the risk for obesity in adulthood.

  10. high-fat diet reduced hepatic CEACAM1 expression and that overexpressing CEACAM1 in liver curtailed diet-induced metabolic abnormalities by protecting hepatic insulin (show INS Proteins) clearance.

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. CEACAM1 mediates bacterial adherence and transcellular transcytosis.

  2. CEACAM1 might play an important role in ovarian tumor progression, especially in tumor metastasis

  3. Osteosarcoma patients with higher CEACAM1 had relatively lower survival compared to those with low CEACAM1 and high serum CEACAM1 level was an independent prognostic factor for osteosarcoma

  4. serum CEACAM1 is elevated over time in progressive melanoma patients who fail to respond to immunotherapy as opposed to responders and stable disease patients.

  5. an MITF (show MITF Proteins)-CEACAM1 axis is suggested as a potential determinant of melanoma progression.

  6. Collectively, these data suggest that vIL (show VIL1 Proteins)-6 modulates endothelial cell migration by upregulating the expression of cellular factors, including CEACAM1.

  7. Taken together, our results demonstrate a systematic down-regulation of CEACAM1 in breast cancer and suggest that a strategy to restore CEACAM1 expression may be helpful for the treatment of breast cancer.

  8. Elevated carcinoembryonic antigen (show CEACAM5 Proteins) expression is associated with recurrence for patients after resection for colorectal liver metastases.

  9. Serum concentrations of CEACAM1 may serve as a useful indicator for the presence of breast cancer

  10. High Carcinoembryonic Antigen (show CEACAM5 Proteins) expression is associated with colon and stomach cancer.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Protein Profile

Protein Summary

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Gene names and symbols associated with CEACAM1

  • carcinoembryonic antigen-related cell adhesion molecule 1 (ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 18 (Ceacam18)
  • 2010110O04Rik protein
  • bb-1 protein
  • BGP protein
  • BGP1 protein
  • BGPI protein
  • BGPR protein
  • C-CAM protein
  • Cc1 protein
  • Ccam1 protein
  • CD66a protein
  • Cea-1 protein
  • Cea-7 protein
  • Cea1 protein
  • Cea7 protein
  • CEACAM1 protein
  • CEACAM8 protein
  • hm:zeh0068 protein
  • Hv-2 protein
  • Hv2 protein
  • mCEA1 protein
  • MGC142545 protein
  • Mhv-1 protein
  • MHVR protein
  • MHVR1 protein
  • mmCGM1 protein
  • mmCGM1a protein
  • mmCGM2 protein
  • zeh0068 protein

Protein level used designations for CEACAM1

carcinoembryonic antigen-related cell adhesion molecule 1 , carcinoembryonic antigen-related cell adhesion molecule 8 , CEACAM1b-3L , CEACAM1b-3S , CEACAM1b-3Ls , CEACAM1b-3Ss , BGP-1 , CEA-related cell adhesion molecule 1 , MHV-R , biliary glycoprotein 1 , biliary glycoprotein D , carcinoembryonic antigen 1 , carcinoembryonic antigen 7 , hepatitis virus (MHV-4) susceptibility , hepatitis virus receptor , murine hepatitis virus receptor , CD66a antigen , antigen CD66 , ATP-dependent taurocolate-carrier protein , C-CAM 105 , CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin) , GP110 , bone gamma-carboxyglutamic acid (Gla) protein , cell-CAM 105 , ecto-ATPase , osteocalcin , pp120 , pp120/ecto-ATPase

GENE ID SPECIES
114465 Danio rerio
404118 Bos taurus
612435 Canis lupus familiaris
26365 Mus musculus
634 Homo sapiens
81613 Rattus norvegicus
72431 Mus musculus
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