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anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Antibodies

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. Additionally we are shipping Cdk5 and Abl Enzyme Substrate 1 Proteins (4) and Cdk5 and Abl Enzyme Substrate 1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CABLES1 91768 Q8TDN4
CABLES1 63955 Q9ESJ1
CABLES1 307585  
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Top anti-Cdk5 and Abl Enzyme Substrate 1 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibod... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of CABLES1 staining in SHSY5Y cells. Formal... Immunohistochemical analysis of CABLES1 staining in human breast cance... 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IF, IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details

CABLES1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Cdk5 and Abl Enzyme Substrate 1 Antibodies

  1. Human Polyclonal CABLES1 Primary Antibody for ELISA, WB - ABIN1534279 : Nusbaum, Zody, Borowsky, Kamal, Kodira, Taylor, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Abouelleil, Allen, Anderson, Bloom, Bugalter, Butler, Cook, DeCaprio, Engels, Garber, Gnirke, Hafez et al.: DNA sequence and analysis of human chromosome 18. ... in Nature 2005 (PubMed)

More Antibodies against Cdk5 and Abl Enzyme Substrate 1 Interaction Partners

Zebrafish Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. cables1 is important for neural differentiation during embryogenesis, in a mechanism that likely involves interactions with the Cdk5 (show CDK5 Antibodies)/p35 (show CDK5R1 Antibodies) kinase pathway.

Human Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease

  2. the results suggest Cables1 as a novel p21 (show CDKN1A Antibodies) regulator through maintaining p21 (show CDKN1A Antibodies) stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21 (show CDKN1A Antibodies).

  3. Results illuminated a dynamic regulatory system through which activated Akt (show AKT1 Antibodies) and 14-3-3 (show YWHAQ Antibodies) work directly together to neutralize a potent tumor suppressor function of Cables1.

  4. The results did not detect a significant association. It indicated that common genetic variations in CDK5 (show CDK5 Antibodies) genes might not play a role in the genetic predisposition to autism.

  5. Analysis of the RT-PCR prducts of the CABLES1 gene showed eight intragenic deletions in its mRNA transcripts; 5/8 are the result of RNA splicing.

  6. Mechanisms of CABLES1 gene inactivation in ovarian cancer development are reported.

Mouse (Murine) Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Loss of Cables1 enhances tumor progression in the Apc (show APC Antibodies)(Min/+) mouse model and activates the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.

  2. Agenesis of the corpus callosum frequency in Cables1(+/TAS (show MAP3K4 Antibodies)) mice was significantly lower than that in Cables1(-/TAS (show MAP3K4 Antibodies)) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS (show MAP3K4 Antibodies)).

  3. Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress.

  4. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood.

Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Antigen Profile

Protein Summary

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CABLES1

  • Cdk5 and Abl enzyme substrate 1 (CABLES1) antibody
  • Cdk5 and Abl enzyme substrate 1 (cables1) antibody
  • Cdk5 and Abl enzyme substrate 1 (CpipJ_CPIJ019832) antibody
  • CDK5 and Abl enzyme substrate 1 (Cables1) antibody
  • Cdk5 and Abl enzyme substrate 1 (Cables1) antibody
  • CABL1 antibody
  • Cables antibody
  • CABLES1 antibody
  • HsT2563 antibody
  • ik3-1 antibody
  • si:dkey-2p18.3 antibody

Protein level used designations for CABLES1

Cdk5 and Abl enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1-like , interactor with CDK3 1 , cdk3-binding protein ik3-1 , interactor-1 with cdk3

GENE ID SPECIES
455335 Pan troglodytes
100059359 Equus caballus
100126070 Danio rerio
100345850 Oryctolagus cuniculus
100479459 Ailuropoda melanoleuca
6054063 Culex quinquefasciatus
100562423 Anolis carolinensis
100603520 Nomascus leucogenys
91768 Homo sapiens
63955 Mus musculus
768914 Gallus gallus
100682687 Canis lupus familiaris
100526114 Sus scrofa
100138286 Bos taurus
307585 Rattus norvegicus
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