CABLES1 antibody (C-Term)

Catalog No. ABIN2789955

The Rabbit Polyclonal anti-CABLES1 antibody is suitable to detect CABLES1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for CABLES1 antibody (C-Term) (ABIN2789955)

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABLES1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CABLES1 Antibody

Binding Specificity: C-Term

Purpose: CABLES1 Antibody - C-terminal region

Sequence: PSYMTTVIDY VKPSDLKKDM NETFKEKFPH IKLTLSKIRS LKREMRKLAQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CABLES1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64759-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Alternative Name: CABLES1

Background:

Background Information: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers.Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Cdk5 and Abl enzyme substrate 1

Alternative Symbols: CABL1, IK3-1, CABLES, HsT2563

Protein Name: CDK5 and ABL1 enzyme substrate 1

Molecular Weight: 42kDa

Gene ID: 91768

NCBI Accession: NP_612384

UniProt: Q8TDN4