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anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) Antibodies

The protein encoded by CDC37 is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. Additionally we are shipping CDC37 Proteins (17) and CDC37 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDC37 11140 Q16543
CDC37 12539 Q61081
CDC37 114562 Q63692
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Top anti-CDC37 Antibodies at antibodies-online.com

Showing 10 out of 124 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of CDC37 on human endothelial lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of CDC37. WI38 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using CDC37 (Phospho-Ser13) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta, using CDC37 (Phospho-Ser13) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit HRP ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$350.90
Details
Human Rabbit FITC ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$355.30
Details
Human Rabbit Alkaline Phosphatase (AP) ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$357.50
Details
Human Rabbit Biotin ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$359.70
Details
Human Rabbit PE ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$360.80
Details
Human Rabbit Streptavidin ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$361.90
Details
Human Rabbit APC ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$363.00
Details

CDC37 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CDC37 Antibodies

  1. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN2484525 : Dai, Kobayashi, Beach: Physical interaction of mammalian CDC37 with CDK4. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN2484525

  2. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN2484530 : Stepanova, Leng, Parker, Harper: Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4. in Genes & development 1996 (PubMed)
    Show all 4 references for ABIN2484530

  3. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN2484531 : Kimura, Rutherford, Miyata, Yahara, Freeman, Yue, Morimoto, Lindquist: Cdc37 is a molecular chaperone with specific functions in signal transduction. in Genes & development 1997 (PubMed)
    Show all 4 references for ABIN2484531

  4. Human Polyclonal CDC37 Primary Antibody for ICC, IF - ABIN2484524 : Gray, Prince, Cheng, Stevenson, Calderwood: Targeting the oncogene and kinome chaperone CDC37. in Nature reviews. Cancer 2008 (PubMed)
    Show all 4 references for ABIN2484524

  5. Dog (Canine) Monoclonal CDC37 Primary Antibody for IF, IP - ABIN968047 : Grammatikakis, Lin, Grammatikakis, Tsichlis, Cochran: p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. in Molecular and cellular biology 1999 (PubMed)
    Show all 3 references for ABIN968047

More Antibodies against CDC37 Interaction Partners

Fruit Fly (Drosophila melanogaster) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

Human Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Apart from these distinct Cdc37/Hsp90 interfaces, binding of the B-Raf protein kinase to the cochaperone is conserved between mammals and nematodes.

  2. Suppressing expression of the cochaperone CDC37 in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.

  3. RIP3 (show RIPK3 Antibodies) activation following the induction of necroptosis requires the activity of an HSP90 (show HSP90 Antibodies) and CDC37 cochaperone complex.

  4. Correlation between PDZK1 (show PDZK1 Antibodies), Cdc37, Akt (show AKT1 Antibodies) and breast cancer malignancy: the role of PDZK1 (show PDZK1 Antibodies) in cell growth through Akt (show AKT1 Antibodies) stabilization by increasing and interacting with Cdc37

  5. The N-terminal tail serves as an intramolecular chaperone ensuring that CDC37 assumes one of two interconvertible states in a manner impacting the interaction of the client binding N-domain and the MC-domains, involved in dimerization and HSP90 (show HSP90 Antibodies) binding.

  6. CDC37 has an important role in chaperoning protein kinases; it stabilizes kinase clients by a mechanism that is not dependent on a substantial direct interaction between CDC37 and HSP90 (show HSP90 Antibodies), but requires HSP90 (show HSP90 Antibodies) activity

  7. As a novel Hsp90 (show HSP90 Antibodies) inhibitor, FW-04-806 binds to the N-terminal of Hsp90 (show HSP90 Antibodies) and inhibits Hsp90 (show HSP90 Antibodies)/Cdc37 interaction, resulting in the disassociation of Hsp90 (show HSP90 Antibodies)/Cdc37/client complexes and the degradation of Hsp90 (show HSP90 Antibodies) client proteins.

  8. CDC37 is a crucial HSP90 (show HSP90 Antibodies)-cofactor for KIT oncogenic expression in gastrointestinal stromal tumors

  9. SGK3 (show SGK3 Antibodies) stability and kinase activation are regulated by the Hsp90 (show HSP90 Antibodies)-Cdc37 chaperone complex.

  10. Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90 (show HSP90 Antibodies)) motility by interaction with N-terminal and middle domain binding sites.

Mouse (Murine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. A series of tyrosine phosphorylation events, involving both p50(Cdc37) and Hsp90 (show HSP90 Antibodies), are minimally sufficient to provide directionality to the chaperone cycle.

  2. Hsp90 (show HSP90 Antibodies)-Cdc37 complex acta (show ACTC1 Antibodies) as an endogenous regulator of noncanonical p38alpha (show MAPK14 Antibodies) activity.

  3. CDC37 binds to Akt (show AKT1 Antibodies) and HSP90 (show HSP90 Antibodies) in the signal transduction pathway in human tumor cells

  4. The interaction between mouse Pem and Cdc37 homolog was then confirmed by glutathione S-transferase (show GSTa2 Antibodies) pull-down assay, and the possible interaction model was suggested.

  5. JAK1 (show JAK1 Antibodies)/2 are client proteins of Hsp90 alpha (show HSP90AA1 Antibodies) and beta; Hsp90 (show HSP90 Antibodies) and CDC37 play a critical role in types I and II interferon (show IFNA Antibodies) pathways

  6. This growth inhibition is partially rescued by expression of ectopic Gli1 (show GLI1 Antibodies), suggesting that Fu may contribute to enhance Hh signaling activity in cancer cells.

Cow (Bovine) Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) interaction partners

  1. Cdc37 has a direct regulatory interaction with endothelial nitric oxide synthase (eNOS (show NOS3 Antibodies)) and may play an important role in mediating the eNOS (show NOS3 Antibodies) protein complex formation.

CDC37 Antigen Profile

Protein Summary

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Gene names and symbols associated with CDC37

  • CG12019 gene product from transcript CG12019-RA (Cdc37) antibody
  • cell division cycle 37 homolog (Cdc37) antibody
  • Hsp90 co-chaperone Cdc37 (cdc37) antibody
  • Hsp90 co-chaperone Cdc37 (AFUA_4G10010) antibody
  • Cell cycle protein necessary for passage of START (CDC37) antibody
  • cell division cycle 37 (CDC37) antibody
  • cell division cycle 37 (Cdc37) antibody
  • cell division cycle 37 homolog (S. cerevisiae) (CDC37) antibody
  • Afu4g10010 antibody
  • cdc37 antibody
  • CG12019 antibody
  • CPDR-1 antibody
  • CPDR-2 antibody
  • Dmel\\CG12019 antibody
  • DROCPDR antibody
  • E(sev)3B antibody
  • p50 antibody
  • p50Cdc37 antibody

Protein level used designations for CDC37

CG12019-PA , Cdc37-PA , cdc37 protein , hsp90 co-chaperone Cdc37 , Hsp90 co-chaperone Cdc37 , hypothetical protein , CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog , cell division cycle 37 homolog , hsp90 chaperone protein kinase-targeting subunit , CDC37 (cell division cycle 37 S. cerevisiae homolog) , p50Cdc37 , CDC37 cell division cycle 37 protein , CDC37 homolog , cell division cycle 37 protein , cell division cycle control protein 37

GENE ID SPECIES
38232 Drosophila melanogaster
724675 Apis mellifera
2541293 Schizosaccharomyces pombe 972h-
3509722 Aspergillus fumigatus Af293
3639210 Candida albicans SC5314
11140 Homo sapiens
12539 Mus musculus
114562 Rattus norvegicus
484955 Canis lupus familiaris
100141402 Sus scrofa
520883 Bos taurus
395430 Gallus gallus
Selected quality suppliers for anti-CDC37 (CDC37) Antibodies
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