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Cell Division Cycle 6 Homolog (S. Cerevisiae) Proteins (CDC6)

The protein encoded by CDC6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. Additionally we are shipping CDC6 Antibodies (159) and CDC6 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDC6 990 Q99741
CDC6 23834 O89033
Rat CDC6 CDC6 360621  
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Top CDC6 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Thermococcus onnurineus His tag   1 mg Log in to see 56 to 66 Days
$3,153.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CDC6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) Interaction Partners

Human Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) interaction partners

  1. CDC6 and Cyclin F (show CCNF Proteins) interact through defined sequence motifs that promote CDC6 ubiquitylation and degradation.

  2. Cdc6 interacts with centrosomes during mitotic cell division.

  3. The current study suggests that miR26a, miR26b, and CDC6 and factors regulating their expression represent potential cancer diagnostic and prognostic markers as well as anticancer targets.

  4. The cell cycle-dependent centrosomal localization of Cdc6 in S and G2 phases suggest a novel function of Cdc6 in centrosomes.

  5. Cdk1 (show CDK1 Proteins) contributes to the nuclear export of Cdc6 at the S-to-G2 transition.

  6. Aberrant expression of both cyclin D1 (show CCND1 Proteins) and CDC6 by YB-1 (show YBX1 Proteins) over-expression may collaboratively participate in lung carcinogenesis.

  7. The Cdc6 is the AAA+ ATPase that assembles prereplicative complexes on replication origins in eukaryotic chromosomes and two more functions in mammalian cells to promote cell proliferation and survival.

  8. These results provided new evidence for the regulatory mechanism of aberrant CDC6 oncogene (show RAB1A Proteins) transcription by FOXM1 (show FOXM1 Proteins) and AR, two highly expressed transcription factors in prostate cancer cells

  9. Two nuclear export signals of Cdc6 work cooperatively and distinctly for the cytoplasmic translocation of Cdc6 phosphorylated by cyclin A (show CCNA2 Proteins)/Cdk2 (show CDK2 Proteins).

  10. ORC/Cdc6/MCM2-7 complex is a new regulatory mechanism for the helicase.

Mouse (Murine) Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) interaction partners

  1. CDK1 (show CDK1 Proteins) activation proceeds with concomitant inhibition by CDC6, which tunes the timing of the M-phase entry during the embryonic cell cycle

  2. Cdc6 continued to block apoptosome assembly induced by a non-cytochrome c (show CYCS Proteins) or some other mechanism, suppressing seemingly unintended apoptosis when promoting cell proliferation

  3. show that MyoD can occupy an E-box within the promoter of Cdc6 and that this association, along with E2F3a, is required for its activity.

  4. CDC6 is essential for spindle formation in mouse oocytes

CDC6 Protein Profile

Protein Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Gene names and symbols associated with CDC6

  • cell division cycle 6 homolog (S. cerevisiae) (CDC6)
  • cell division cycle 6 (CDC6)
  • cell division cycle 6 (Cdc6)
  • CDC18L protein
  • HsCDC6 protein
  • HsCDC18 protein

Protein level used designations for CDC6

CDC6 cell division cycle 6 homolog , CDC6-related protein , cdc18-related protein , cell division control protein 6 homolog , cell division cycle 6 homolog , p62(cdc6) , CDC18(S.pombe)

GENE ID SPECIES
100067788 Equus caballus
990 Homo sapiens
23834 Mus musculus
360621 Rattus norvegicus
515301 Bos taurus
480527 Canis lupus familiaris
100522031 Sus scrofa
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