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The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. Additionally we are shipping Centromere Protein N Antibodies (25) and Centromere Protein N Proteins (7) and many more products for this protein.
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Study demonstrate that the CENP-L (show CENPL ELISA Kits)-N complex plays a crucial role at the core of the 16-subunit Constitutive Centromere-Associated Network through interactions with CENP-C (show CENPC1 ELISA Kits) and CENP-H (show CENPH ELISA Kits)-I-KM.
CENP-N is bound to kinetochores during S phase and G2, but is absent from kinetochores during mitosis and G1.
Data suggest that CENP-N interprets the information encoded within CENP-A (show CENPA ELISA Kits) nucleosomes and recruits other proteins to centromeric chromatin that are required for centromere function and propagation.
The protein encoded by this gene forms part of the nucleosome-associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
, unm hi3634
, centromere protein N
, centromere protein N-A
, centromere protein N-B
, Centromere protein N-B
, centromere protein N-like
, interphase centromere complex protein 32