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Ceramide Synthase 4 Proteins (CERS4)

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. Additionally we are shipping Ceramide Synthase 4 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CERS4 67260 Q9D6J1
Rat CERS4 CERS4 304208  
CERS4 79603 Q9HA82
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Top Ceramide Synthase 4 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CERS4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Ceramide Synthase 4 (CERS4) Interaction Partners

Mouse (Murine) Ceramide Synthase 4 (CERS4) interaction partners

  1. CerS4-directed epidermal ceramide composition is essential to control hair follicle stem and progenitor cell behavior potentially through its regulation of BMP and Wnt (show WNT2 Proteins) signaling

  2. Loss of CerS4 protein leads to an altered lipid composition of the sebum, which is more solidified and therefore might cause progressive hair loss due to physical blocking of the hair canal.

  3. Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1 (show CERS1 Proteins)-Cers6 (show CERS6 Proteins)) activity in macrophages is responsible for the accumulation of ceramide.

  4. Lag1p family members trh1 and trh4 (show LASS5 Proteins) regulate (dihydro)ceramide synthases responsible for production of sphingolipids containing different fatty acids

Human Ceramide Synthase 4 (CERS4) interaction partners

  1. mRNA level of CerS4 is higher in cancerous cell lines and decreases following the induction of apoptosis.

  2. Co-expression of CerS2 (show CERS2 Proteins) with CerS4/CerS6 (show CERS6 Proteins) reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation.

  3. The linkage and association of phospholipid transfer protein (show PLTP Proteins) activity to LASS4 were studied.

Ceramide Synthase 4 (CERS4) Protein Profile

Protein Summary

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).

Gene names and symbols associated with Ceramide Synthase 4 Proteins (CERS4)

  • ceramide synthase 4a (cers4a)
  • ceramide synthase 4 (Cers4)
  • ceramide synthase 4 (CERS4)
  • ceramide synthase 4 (LASS4)
  • 2900019C14Rik protein
  • LASS4 protein
  • Trh1 protein

Protein level used designations for Ceramide Synthase 4 Proteins (CERS4)

LAG1 longevity assurance homolog 4 , LAG1 homolog, ceramide synthase 4 , TRAM homolog 1 , longevity assurance homolog 4 , translocating chain-associating membrane protein homolog 1 , longevity assurance-like protein 4

GENE ID SPECIES
259250 Danio rerio
67260 Mus musculus
304208 Rattus norvegicus
79603 Homo sapiens
485008 Canis lupus familiaris
100127167 Sus scrofa
505233 Bos taurus
428318 Gallus gallus
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