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Chemokine (C-C Motif) Receptor 9 Proteins (CCR9)

The protein encoded by CCR9 is a member of the beta chemokine receptor family. Additionally we are shipping Chemokine (C-C Motif) Receptor 9 Antibodies (187) and Chemokine (C-C Motif) Receptor 9 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCR9 59289 O08707
CCR9 1238 O00590
Rat CCR9 CCR9 282832  
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Top Chemokine (C-C Motif) Receptor 9 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$426.92
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 3 to 4 Days
$310.00
Details

CCR9 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human ,

More Proteins for Chemokine (C-C Motif) Receptor 9 (CCR9) Interaction Partners

Mouse (Murine) Chemokine (C-C Motif) Receptor 9 (CCR9) interaction partners

  1. CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue.

  2. data indicate that in addition to acting as a gut (show GUSB Proteins)-homing molecule, CCR9 signaling shapes immune responses by inhibiting Treg cell development

  3. Data suggest that blocking CC chemokine receptor (show CCR1 Proteins) 9 (CCR9) may represent a novel safe therapy for rheumatoid arthritis (RA).

  4. activation of Notch1 (show NOTCH1 Proteins) has a dominant-negative effect on Ccr9 transcription and that Notch1 (show NOTCH1 Proteins) and E proteins control the dynamic expression of Ccr9 during T cell development.

  5. ACKR2 can regulate fetal (show CCL1 Proteins) growth, placental structure, and neonatal mortality in mice.

  6. Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.

  7. some cells, including plasmacytoid dendritic cells, can express both CCR2 (show CCR2 Proteins) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (show CCL2 Proteins)-scavenging potential in vitro and in vivo; and that CCR2 (show CCR2 Proteins) is a much more effective CCL2 (show CCL2 Proteins) scavenger than ACKR2.

  8. CCR9/CCL25 (show CCL25 Proteins) is involved in acute skin transplantation rejection and anti-CCL25 (show CCL25 Proteins) strategies might be useful in preventing acute rejection.

  9. Accumulated CD11b (show ITGAM Proteins)(+) macrophages are critical for activating hepatic stellate cells through the CCR9/CCL25 (show CCL25 Proteins) axis and therefore promote liver fibrosis.

  10. CCR9-expressed plasmacytoid dendritic cells are possibly small intestine regulatory, antigen-presenting cells that suppress intestinal inflammation.

Human Chemokine (C-C Motif) Receptor 9 (CCR9) interaction partners

  1. Studies indicate important roles played by chemokine ligand 25 (CCL25 (show CCL25 Proteins))/chemokine receptor (show CCR1 Proteins) 9 (CCR9) in tumorigenesis, tumor chemoresistance and metastasis.

  2. CCR9 and Integrin-beta7 expression has a differential effect on graft fate during acute graft-versus-host disease (GVHD) of the liver depending on the GVHD target tissue.

  3. CCR9 mRNA and protein levels were significantly increased in the nasopharyngeal carcinoma group compared with the control group.

  4. CCR9-CCL25 (show CCL25 Proteins) interaction promoted proliferation and suppressed apoptosis of non-small cell lung cancer cells by activating the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway.

  5. CCR9 could be beneficial in predicting lymph node metastasis, and it might act as a novel prognostic biomarker for lung adenocarcinoma.

  6. We also show that primary tumors can be modeled in immunocompetent mice by microinjecting CCR9-expressing cancer cell lines into early-stage mouse blastocysts, which induces central immune tolerance

  7. High CCR9 expression is associated with the pathogenesis of ulcerative colitis.

  8. Expression of CCR9 and CCL25 (show CCL25 Proteins), the only natural ligand of CCR9, was significantly higher (p<0.0001) in NSCLC tissues and serum respectively, compared to their respective controls.

  9. activation of Notch1 (show NOTCH1 Proteins) has a dominant-negative effect on Ccr9 transcription and that Notch1 (show NOTCH1 Proteins) and E proteins control the dynamic expression of Ccr9 during T cell development.

  10. ACKR2 mediates chemokine (show CCL1 Proteins) scavenging by primary human trophoblasts.

Chemokine (C-C Motif) Receptor 9 (CCR9) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CCR9

  • chemokine (C-C motif) receptor 9 (CCR9)
  • atypical chemokine receptor 2 (Ackr2)
  • atypical chemokine receptor 2 (ACKR2)
  • chemokine (C-C motif) receptor 9 (Ccr9)
  • A130091K22Rik protein
  • AI464239 protein
  • CC-CKR-9 protein
  • CCBP2 protein
  • CCR9 protein
  • CCR10 protein
  • CDw199 protein
  • CMKBR9 protein
  • Cmkbr10 protein
  • D6 protein
  • GPR-9-6 protein
  • GPR28 protein
  • hD6 protein

Protein level used designations for CCR9

C-C chemokine receptor D6 , D6 beta-chemokine receptor , chemokine binding protein 2 , chemokine-binding protein 2 , chemokine-binding protein D6 , CC-chemokine-binding receptor JAB61 , chemokine (C-C motif) receptor 9 , chemokine (C-C) receptor 9 , chemokine receptor CCR-10 , chemokine receptor CCR-9 , chemokine receptor D6 , C-C chemokine receptor type 9 , G protein-coupled receptor 28 , C-C CKR-9 , CC-CKR-9 , CCR-9 , chemokine C-C receptor 10 , chemokine C-C motif receptor 9

GENE ID SPECIES
100065535 Equus caballus
59289 Mus musculus
1238 Homo sapiens
10803 Homo sapiens
12769 Mus musculus
282832 Rattus norvegicus
484793 Canis lupus familiaris
530951 Bos taurus
678667 Ovis aries
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